This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pRK5-myc-Miro2
catalog :
47891
citations: 7
Reference
Wang F, Chen X, Cheng H, Song L, Liu J, Caplan S, et al. MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking. EMBO Rep. 2021;22:e52006 pubmed publisher
Guillén Samander A, Leonzino M, Hanna M, Tang N, Shen H, De Camilli P. VPS13D bridges the ER to mitochondria and peroxisomes via Miro. J Cell Biol. 2021;220: pubmed publisher
Chung E, Choi Y, Park J, Nah W, Park J, Jung Y, et al. Intracellular delivery of Parkin rescues neurons from accumulation of damaged mitochondria and pathological α-synuclein. Sci Adv. 2020;6:eaba1193 pubmed publisher
Bocanegra J, Fujita B, Melton N, Cowan J, Schinski E, Tamir T, et al. The MyMOMA domain of MYO19 encodes for distinct Miro-dependent and Miro-independent mechanisms of interaction with mitochondrial membranes. Cytoskeleton (Hoboken). 2019;: pubmed publisher
Walch L, Pellier E, Leng W, Lakisic G, Gautreau A, Contremoulins V, et al. GBF1 and Arf1 interact with Miro and regulate mitochondrial positioning within cells. Sci Rep. 2018;8:17121 pubmed publisher
López Doménech G, Higgs N, Vaccaro V, Ros H, Arancibia Carcamo I, Macaskill A, et al. Loss of Dendritic Complexity Precedes Neurodegeneration in a Mouse Model with Disrupted Mitochondrial Distribution in Mature Dendrites. Cell Rep. 2016;17:317-327 pubmed publisher
Fransson A, Ruusala A, Aspenstrom P. Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis. J Biol Chem. 2003;278:6495-502 pubmed
product information
Catalog Number :
47891
Product Name :
pRK5-myc-Miro2
article :
doi10.1074/jbc.M208609200
id7174
pubmed_id12482879
bacterial resistance :
Ampicillin
cloning :
backbonepRK5-myc
backbone_mutationMyc inserted into EcoRI/PstI site (sites destroyed).
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Expresses myc tagged Miro2
origin :
37
pi :
alt_names
RHOT2
ras homolog family member T2
Miro-2
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5BglII
promoterCMV
sequencing_primer_3SV40pA-R
sequencing_primer_5SP6
site_3_destroyed
site_5_destroyed1
entrez_gene
aliasesARHT2, C16orf39, MIRO-2, MIRO2, RASL
geneRHOT2
id89941
genbank_ids
AJ517413
mutation
nameMiro2
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagmyc
resistance markers :
1683
tags :
Low Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA