This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCDH-puro-Bcl-XL
catalog :
46972
citations: 9
Reference
Pourzia A, Olson M, Bailey S, Boroughs A, Aryal A, Ryan J, et al. Quantifying requirements for mitochondrial apoptosis in CAR T killing of cancer cells. Cell Death Dis. 2023;14:267 pubmed publisher
Mathias T, Ju J, Lee R, Thompson K, Mull M, Annis D, et al. Tubulin Carboxypeptidase Activity Promotes Focal Gelatin Degradation in Breast Tumor Cells and Induces Apoptosis in Breast Epithelial Cells That Is Overcome by Oncogenic Signaling. Cancers (Basel). 2022;14: pubmed publisher
Yanagimura N, Takeuchi S, Fukuda K, Arai S, Tanimoto A, Nishiyama A, et al. STAT3 inhibition suppresses adaptive survival of ALK-rearranged lung cancer cells through transcriptional modulation of apoptosis. NPJ Precis Oncol. 2022;6:11 pubmed publisher
Booth L, West C, Von Hoff D, Kirkwood J, Dent P. GZ17-6.02 Interacts With [MEK1/2 and B-RAF Inhibitors] to Kill Melanoma Cells. Front Oncol. 2021;11:656453 pubmed publisher
Dai Y, Shaikho E, Perez J, Wilson C, Liu L, White M, et al. BCL2L1 is associated with γ-globin gene expression. Blood Adv. 2019;3:2995-3001 pubmed publisher
Inglés M, Mas Bargues C, Berna Erro A, Matheu A, Sanchis P, Avellana J, et al. Centenarians overexpress pluripotency-related genes. J Gerontol A Biol Sci Med Sci. 2018;: pubmed publisher
Kozaki T, Komano J, Kanbayashi D, Takahama M, Misawa T, Satoh T, et al. Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response. Proc Natl Acad Sci U S A. 2017;114:2681-2686 pubmed publisher
Borras C, Abdelaziz K, Gambini J, Serna E, Inglés M, De la Fuente M, et al. Human exceptional longevity: transcriptome from centenarians is distinct from septuagenarians and reveals a role of Bcl-xL in successful aging. Aging (Albany NY). 2016;8:3185-3208 pubmed publisher
Cheng Z, Gong Y, Ma Y, Lu K, Lu X, Pierce L, et al. Inhibition of BET bromodomain targets genetically diverse glioblastoma. Clin Cancer Res. 2013;19:1748-59 pubmed publisher
product information
Catalog Number :
46972
Product Name :
pCDH-puro-Bcl-XL
article :
doi10.1158/1078-0432.CCR-12-3066
id7005
pubmed_id23403638
bacterial resistance :
Ampicillin
cloning :
backbonePCDH-CMV-MCS-EF1-PURO
backbone_mutation
backbone_originSystem Biosciences
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
growth notes :
Bcl-xL was cut from 3120 pSFFV-neo Bcl-XL(Addgene #8749) and subcloned into the EcoRI sites of pCDH-CMV-MCS-EF1-Puro.
growth strain :
lentiviral expression of Bcl-XL
origin :
37
pi :
alt_names
Bcl-XL
BCL2-like 1
BCLX
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5EcoRI
promoterCMV
sequencing_primer_3
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBCL-XL/S, BCL2L, BCLX, Bcl-X, PPP1R52
geneBCL2L1
id598
genbank_ids
mutation
nameBCL2L1
shRNA_sequence
size700
species
9606
Homo sapiens
tags
resistance markers :
1651
tags :
Unknown
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA