STAT3(Y705F)-TAL-Luc | Addgene 46933 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

STAT3(Y705F)-TAL-Luc

catalog :

46933

citations: 3

Reference
Ye M, Huang W, Liu R, Kong Y, Liu Y, Chen X, et al. Synergistic Activity of the HSP90 Inhibitor Ganetespib With Lapatinib Reverses Acquired Lapatinib Resistance in HER2-Positive Breast Cancer Cells. Front Pharmacol. 2021;12:651516 pubmed publisher
Dimri S, Arora R, Jasani A, De A. Dynamic monitoring of STAT3 activation in live cells using a novel STAT3 Phospho-BRET sensor. Am J Nucl Med Mol Imaging. 2019;9:321-334 pubmed
Dabir S, Kluge A, Dowlati A. The association and nuclear translocation of the PIAS3-STAT3 complex is ligand and time dependent. Mol Cancer Res. 2009;7:1854-60 pubmed publisher

product information

Catalog Number :

46933

Product Name :

STAT3(Y705F)-TAL-Luc

article :

doi	10.1158/1541-7786.MCR-09-0313
id	6992
pubmed_id	19903771

bacterial resistance :

Ampicillin

cloning :

backbone

pTAL-Luc

backbone_mutation

backbone_origin

Clontech

backbone_size

5000

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Luciferase

growth strain :

Luciferase Reporter for mutant STAT3

origin :

pi :

alt_names

STAT3

signal transducer and activator of transcription 3 (acute-phase response factor)

cloning

clone_method	Restriction Enzyme
cloning_site_3	XhoI
cloning_site_5	NheI
promoter	TA Luciferase
sequencing_primer_3
sequencing_primer_5	5'-CGGGAGGTACTTGGAGCG-3'
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	ADMIO, ADMIO1, APRF, HIES
gene	STAT3
id	6774

genbank_ids

mutation

Tyrosine 705 to Phenylalanine

name

STAT3(Y705F)

shRNA_sequence

size

2351

species

9606

Homo sapiens