This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pGEX Csk-SH2
catalog :
46420
citations: 3
Reference
Luo L, Wall A, Tong S, Hung Y, Xiao Z, Tarique A, et al. TLR Crosstalk Activates LRP1 to Recruit Rab8a and PI3K? for Suppression of Inflammatory Responses. Cell Rep. 2018;24:3033-3044 pubmed publisher
Luo L, Tong S, Wall A, Khromykh T, Sweet M, Stow J. Development of SH2 probes and pull-down assays to detect pathogen-induced, site-specific tyrosine phosphorylation of the TLR adaptor SCIMP. Immunol Cell Biol. 2017;95:564-570 pubmed publisher
Machida K, Thompson C, Dierck K, Jablonowski K, Kärkkäinen S, Liu B, et al. High-throughput phosphotyrosine profiling using SH2 domains. Mol Cell. 2007;26:899-915 pubmed
product information
Catalog Number :
46420
Product Name :
pGEX Csk-SH2
article :
doi10.1016/j.molcel.2007.05.031
id6931
pubmed_id17588523
bacterial resistance :
Ampicillin
cloning :
backbonepGEX6P1
backbone_mutation
backbone_originGE Healthcare Biosciences
backbone_size4900
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Bacterial Expression
growth notes :
The molecular weight of the GST fusion protein is approximately 37 kDa
origin :
37
pi :
alt_names
CSK
MGC117393; CSK
cloning
clone_methodRestriction Enzyme
cloning_site_3NotI
cloning_site_5BamHI
promoterTac
sequencing_primer_3pGEX-3
sequencing_primer_5pGEX-5
site_3_destroyed
site_5_destroyed
entrez_gene
aliases
geneCSK
id1445
genbank_ids
mutationcontains amino acids 74-177
nameCsk
shRNA_sequence
size329
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagGST
locationN terminal on backbone
tagPreScission
resistance markers :
1624
tags :
Low Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA