This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCI-EGFP-NR1 wt
catalog :
45446
citations: 7
Reference
Angelini C, Morellato A, Alfieri A, Pavinato L, Cravero T, Bianciotto O, et al. p140Cap regulates the composition and localization of the NMDAR complex in synaptic lipid rafts. J Neurosci. 2022;42:7183-200 pubmed publisher
Rosendo Pineda M, Vicente J, Vivas O, Pacheco J, Loza Huerta A, Sampieri A, et al. Phosphorylation of NMDA receptors by cyclin B/CDK1 modulates calcium dynamics and mitosis. Commun Biol. 2020;3:665 pubmed publisher
Zhang Z, Bai H, Guo Z, Li H, Diao X, Zhang T, et al. Ubiquitination and functional modification of GluN2B subunit-containing NMDA receptors by Cbl-b in the spinal cord dorsal horn. Sci Signal. 2020;13: pubmed publisher
Washburn H, Xia N, Zhou W, Mao Y, Dalva M. Positive surface charge of GluN1 N-terminus mediates the direct interaction with EphB2 and NMDAR mobility. Nat Commun. 2020;11:570 pubmed publisher
Yang L, Bai H, Zhang Z, Liu J, Suo Z, Yang X, et al. Disruption of SHP1/NMDA receptor signaling in spinal cord dorsal horn alleviated inflammatory pain. Neuropharmacology. 2018;137:104-113 pubmed publisher
Sequerra E, Goyal R, Castro P, Levin J, Borodinsky L. NMDA Receptor Signaling Is Important for Neural Tube Formation and for Preventing Antiepileptic Drug-Induced Neural Tube Defects. J Neurosci. 2018;38:4762-4773 pubmed publisher
Barria A, Malinow R. Subunit-specific NMDA receptor trafficking to synapses. Neuron. 2002;35:345-53 pubmed
product information
Catalog Number :
45446
Product Name :
pCI-EGFP-NR1 wt
article :
doi10.1016/S0896-6273(02)00776-6
id6702
pubmed_id12160751
bacterial resistance :
Ampicillin
cloning :
backbonepCI
backbone_mutation
backbone_originPromega
backbone_size4006
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
NMDAR1
Grin1
GluN1
cloning
clone_methodRestriction Enzyme
cloning_site_3NotI
cloning_site_5SalI
promoterCMV
sequencing_primer_3EBV-rev
sequencing_primer_5T7; chim-int-F (TCTTACTGACATCCACTTTGCC)
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesGluN1, NMDAR1, NR1
geneGrin1
id24408
genbank_ids
mutationEGFP inserted after the predicted signal peptide cleavage site (after amino acid residue 26)
nameNR1
shRNA_sequence
size5000
species
10116
Rattus norvegicus
tags
locationN terminal on insert
tagEGFP
plasmid copy :
Rat NMDA receptor genes originally cloned by Shigetada Nakanishi (PMID: 1834949)
resistance markers :
1547
671
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA