This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCI-EGFP-NR2a wt
catalog :
45445
citations: 6
Reference
Beesley S, Gunjan A, Kumar S. Visualizing the triheteromeric N-methyl-D-aspartate receptor subunit composition. Front Synaptic Neurosci. 2023;15:1156777 pubmed publisher
Angelini C, Morellato A, Alfieri A, Pavinato L, Cravero T, Bianciotto O, et al. p140Cap regulates the composition and localization of the NMDAR complex in synaptic lipid rafts. J Neurosci. 2022;42:7183-200 pubmed publisher
Zhang Z, Bai H, Guo Z, Li H, Diao X, Zhang T, et al. Ubiquitination and functional modification of GluN2B subunit-containing NMDA receptors by Cbl-b in the spinal cord dorsal horn. Sci Signal. 2020;13: pubmed publisher
Lu X, Zhang Q, Wang T. The second PDZ domain of scaffold protein Frmpd2 binds to GluN2A of NMDA receptors. Biochem Biophys Res Commun. 2019;: pubmed publisher
Yang L, Bai H, Zhang Z, Liu J, Suo Z, Yang X, et al. Disruption of SHP1/NMDA receptor signaling in spinal cord dorsal horn alleviated inflammatory pain. Neuropharmacology. 2018;137:104-113 pubmed publisher
Barria A, Malinow R. Subunit-specific NMDA receptor trafficking to synapses. Neuron. 2002;35:345-53 pubmed
product information
Catalog Number :
45445
Product Name :
pCI-EGFP-NR2a wt
article :
doi10.1016/S0896-6273(02)00776-6
id6702
pubmed_id12160751
bacterial resistance :
Ampicillin
cloning :
backbonepCI
backbone_mutation
backbone_originPromega
backbone_size4006
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
NMDAR2A
GRIN2a
GluN2a
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5NheI
promoterCMV
sequencing_primer_3EBV-rev
sequencing_primer_5T7; chim-int-F (TCTTACTGACATCCACTTTGCC)
site_3_destroyed1
site_5_destroyed1
entrez_gene
aliasesGluN2A, NMDAR2A, NR2A
geneGrin2a
id24409
genbank_ids
D13211.1
BAA02498.1
mutationEGFP inserted after the predicted signal peptide cleavage site (after amino acid residue 21)
nameNR2A
shRNA_sequence
size6000
species
10116
Rattus norvegicus
tags
locationN terminal on insert
tagEGFP
plasmid copy :
Rat NMDA receptor genes originally cloned by Shigetada Nakanishi (PMID: 1834949)
resistance markers :
1547
671
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA