| Reference |
|---|
Sun Y, Xu C, Jiang Z, Jiang X. DEF6(differentially exprehomolog) exacerbates pathological cardiac hypertrophy via RAC1. Cell Death Dis. 2023;14:483 pubmed publisher |
Jiang L, Zhao J, Yang Q, Li M, Liu H, Xiao X, et al. Lysosomal-associated protein transmembrane 5 ameliorates non-alcoholic steatohepatitis by promoting the degradation of CDC42 in mice. Nat Commun. 2023;14:2654 pubmed publisher |
Wu Y, Li J, Li C, Lu S, Wei X, Li Y, et al. Fat mass and obesity-associated factor (FTO)-mediated N6-methyladenosine regulates spermatogenesis in an age-dependent manner. J Biol Chem. 2023;299:104783 pubmed publisher |
Yao X, Dong R, Hu S, Liu Z, Cui J, Hu F, et al. Tripartite motif 38 alleviates the pathological process of NAFLD-NASH by promoting TAB2 degradation. J Lipid Res. 2023;64:100382 pubmed publisher |
Hu J, Zhou B, Lin X, Zhang Q, Guan F, Sun L, et al. Impaired bone strength and bone microstructure in a novel early-onset osteoporotic rat model with a clinically relevant PLS3 mutation. elife. 2023;12: pubmed publisher |
Niu H, Lei A, Tian H, Yao W, Liu Y, Li C, et al. Scd1 Deficiency in Early Embryos Affects Blastocyst ICM Formation through RPs-Mdm2-p53 Pathway. Int J Mol Sci. 2023;24: pubmed publisher |
Ghanam A, Ke S, Wang S, Elgendy R, Xie C, Wang S, et al. Alternative transcribed 3' isoform of long non-coding RNA Malat1 inhibits mouse retinal oxidative stress. iScience. 2023;26:105740 pubmed publisher |
Zhao L, Li M, Yin Z, Lv L, Zhou M, Wang Y, et al. Development of a Lung Vacancy Mouse Model through CRISPR/Cas9-Mediated Deletion of Thyroid Transcription Factor 1 Exon 2. Cells. 2022;11: pubmed publisher |
Yang L, Xiao W, Li H, Hao Z, Liu G, Zhang D, et al. E3 ubiquitin ligase RNF5 attenuates pathological cardiac hypertrophy through STING. Cell Death Dis. 2022;13:889 pubmed publisher |
Tian H, Niu H, Luo J, Yao W, Gao W, Wen Y, et al. Effects of CRISPR/Cas9-mediated stearoyl-Coenzyme A desaturase 1 knockout on mouse embryo development and lipid synthesis. Peerj. 2022;10:e13945 pubmed publisher |
Holmquist C, He W, Meganck R, Marzluff W. Knockouts of TUT7 and 3'hExo show that they cooperate in histone mRNA maintenance and degradation. RNA. 2022;28:1519-1533 pubmed publisher |
Liu X, Zang C, Wu Y, Meng R, Chen Y, Jiang T, et al. Homeodomain-interacting protein kinase HIPK4 regulates phosphorylation of manchette protein RIMBP3 during spermiogenesis. J Biol Chem. 2022;298:102327 pubmed publisher |
Udden S, Wang Q, Kumar S, Malladi V, Wu S, Wei S, et al. Targeting ESR1 mutation-induced transcriptional addiction in breast cancer with BET inhibition. JCI Insight. 2022;7: pubmed publisher |
Chen J, Gao C, Luo M, Zheng C, Lin X, Ning Y, et al. MicroRNA-202 safeguards meiotic progression by preventing premature SEPARASE-mediated REC8 cleavage. EMBO Rep. 2022;:e54298 pubmed publisher |
Huang X, Bashkenova N, Hong Y, Lyu C, Guallar D, Hu Z, et al. A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency. Cell Rep. 2022;39:110928 pubmed publisher |
Cheng L, Xu C, Chen Y, Li J, Wang J, Xiao J, et al. DEC1 represses cardiomyocyte hypertrophy by recruiting PRP19 as an E3 ligase to promote ubiquitination-proteasome-mediated degradation of GATA4. J Mol Cell Cardiol. 2022;169:96-110 pubmed publisher |
Xu K, Yu H, Chen S, Zhang Y, Guo J, Yang C, et al. Production of Triple-Gene (GGTA1, B2M and CIITA)-Modified Donor Pigs for Xenotransplantation. Front Vet Sci. 2022;9:848833 pubmed publisher |
Zhou S, Kalds P, Luo Q, Sun K, Zhao X, Gao Y, et al. Optimized Cas9:sgRNA delivery efficiently generates biallelic MSTN knockout sheep without affecting meat quality. BMC Genomics. 2022;23:348 pubmed publisher |
Baba A, Suwada T, Muta S, Kuhara S, Tashiro K. Prdm12 regulates inhibitory neuron differentiation in mouse embryonal carcinoma cells. Cytotechnology. 2022;74:329-339 pubmed publisher |
Mo X, Kazmi H, Preston Alp S, Zhou B, Zaidi M. Interferon-gamma induces melanogenesis via post-translational regulation of tyrosinase. Pigment Cell Melanoma Res. 2022;35:342-355 pubmed publisher |
Yamaguchi N, Zhang Z, Schneider T, Wang B, Panozzo D, Knaut H. Rear traction forces drive adherent tissue migration in vivo. Nat Cell Biol. 2022;24:194-204 pubmed publisher |
Wang X, Xiong J, Zhou D, Zhang S, Wang L, Tian Q, et al. TRIM34 modulates influenza virus-activated programmed cell death by targeting Z-DNA-binding protein 1 for K63-linked polyubiquitination. J Biol Chem. 2022;298:101611 pubmed publisher |
Xu W, Zhang Y, Qin D, Gui Y, Wang S, Du G, et al. Transcription factor-like 5 is a potential DNA/RNA-binding protein essential for maintaining male fertility in mice. J Cell Sci. 2021;: pubmed publisher |
Zhi M, Zhang J, Tang Q, Yu D, Gao S, Gao D, et al. Generation and characterization of stable pig pregastrulation epiblast stem cell lines. Cell Res. 2021;: pubmed publisher |
Liu S, Zhang J, Kherraf Z, Sun S, Zhang X, Cazin C, et al. CFAP61 is required for sperm flagellum formation and male fertility in human and mouse. Development. 2021;148: pubmed publisher |
Lu S, Gu Y, Wu Y, Yang S, Li C, Meng L, et al. Bi-allelic variants in human WDR63 cause male infertility via abnormal inner dynein arms assembly. Cell Discov. 2021;7:110 pubmed publisher |
Tu H, Zhang A, Fu X, Xu S, Bai X, Wang H, et al. SMPX Deficiency Causes Stereocilia Degeneration and Progressive Hearing Loss in CBA/CaJ Mice. Front Cell Dev Biol. 2021;9:750023 pubmed publisher |
Hou D, Fu H, Zheng Y, Lu D, Ma Y, Yin Y, et al. Uncoupling protein 1 knockout aggravates isoproterenol-induced acute myocardial ischemia via AMPK/mTOR/PPARα pathways in rats. Transgenic Res. 2021;: pubmed publisher |
Zhang B, Gao L, Yang Q, Liu Y, Yu X, Shen J, et al. Role of GALNT4 in protecting against cardiac hypertrophy through ASK1 signaling pathway. Cell Death Dis. 2021;12:980 pubmed publisher |
Pang Y, Ma M, Wang D, Li X, Jiang L. TANK Promotes Pressure Overload Induced Cardiac Hypertrophy via Activating AKT Signaling Pathway. Front Cardiovasc Med. 2021;8:687540 pubmed publisher |
Zhang J, He X, Wu H, Zhang X, Yang S, Liu C, et al. Loss of DRC1 function leads to multiple morphological abnormalities of the sperm flagella and male infertility in human and mouse. Hum Mol Genet. 2021;: pubmed publisher |
Feng W, Simpson D, Cho J, Carvajal Garcia J, Smith C, Headley K, et al. Marker-free quantification of repair pathway utilization at Cas9-induced double-strand breaks. Nucleic Acids Res. 2021;49:5095-5105 pubmed publisher |
Oh T, Lee M, Lee Y, Kim G, Lee D, You J, et al. PGC1α Loss Promotes Lung Cancer Metastasis through Epithelial-Mesenchymal Transition. Cancers (Basel). 2021;13: pubmed publisher |
Xiang M, Yang F, Zhou Y, Li W, Zou Y, Ye P, et al. LITAF acts as a novel regulator for pathological cardiac hypertrophy. J Mol Cell Cardiol. 2021;156:82-94 pubmed publisher |
Zhang Z, Xiong T, Yao S, Wei M, Chen M, Lin D, et al. RNF115 plays dual roles in innate antiviral responses by catalyzing distinct ubiquitination of MAVS and MITA. Nat Commun. 2020;11:5536 pubmed publisher |
Bian X, Liu J, Yang Q, LIU Y, Jia W, Zhang X, et al. MicroRNA-210 regulates placental adaptation to maternal hypoxic stress during pregnancy†. Biol Reprod. 2021;104:418-429 pubmed publisher |
Yan P, Lu J, Niu J, Gao J, Zhang M, Yin Y, et al. LncRNA Platr22 promotes super-enhancer activity and stem cell pluripotency. J Mol Cell Biol. 2020;: pubmed publisher |
Hui X, Hu F, Liu J, Li C, Yang Y, Shu S, et al. FBXW5 acts as a negative regulator of pathological cardiac hypertrophy by decreasing the TAK1 signaling to pro-hypertrophic members of the MAPK signaling pathway. J Mol Cell Cardiol. 2021;151:31-43 pubmed publisher |
Wan Q, Kong D, Liu Q, Guo S, Wang C, Zhao Y, et al. Congestive heart failure in COX2 deficient rats. Sci China Life Sci. 2020;: pubmed publisher |
Li Z, Fu X, Chai C, Sun F, Xiao F, Huang Y, et al. A single copy of large tumor suppressor 1 or large tumor suppressor 2 is sufficient for normal hematopoiesis. Chin Med J (Engl). 2020;133:1943-1951 pubmed publisher |
Zhang X, Lei F, Wang X, Deng K, Ji Y, Zhang Y, et al. NULP1 Alleviates Cardiac Hypertrophy by Suppressing NFAT3 Transcriptional Activity. J Am Heart Assoc. 2020;9:e016419 pubmed publisher |
Amalfi S, Molina G, Bevacqua R, López M, Taboga O, Alfonso V. Baculovirus Transduction in Mammalian Cells Is Affected by the Production of Type I and III Interferons, Which Is Mediated Mainly by the cGAS-STING Pathway. J Virol. 2020;94: pubmed publisher |
Zhang J, Zhang D, Li Y, Wu L, Liang C, Yao R, et al. Myotubularin-related protein 14 suppresses cardiac hypertrophy by inhibiting Akt. Cell Death Dis. 2020;11:140 pubmed publisher |
Xu J, Zheng Z, Du X, Shi B, Wang J, Gao D, et al. A cytokine screen using CRISPR-Cas9 knock-in reporter pig iPS cells reveals that Activin A regulates NANOG. Stem Cell Res Ther. 2020;11:67 pubmed publisher |
Lu Z, Liu Z, Mao W, Wang X, Zheng X, Chen S, et al. Locus-specific DNA methylation of Mecp2 promoter leads to autism-like phenotypes in mice. Cell Death Dis. 2020;11:85 pubmed publisher |
Cortez L, Brown A, Dennis M, Collins C, Brown A, Mitchell D, et al. APOBEC3A is a prominent cytidine deaminase in breast cancer. PLoS Genet. 2019;15:e1008545 pubmed publisher |
Luo X, He Y, Zhang C, He X, Yan L, Li M, et al. Trio deep-sequencing does not reveal unexpected off-target and on-target mutations in Cas9-edited rhesus monkeys. Nat Commun. 2019;10:5525 pubmed publisher |
Song G, Zhang F, Zhang X, Gao X, Zhu X, Fan D, et al. AcrIIA5 Inhibits a Broad Range of Cas9 Orthologs by Preventing DNA Target Cleavage. Cell Rep. 2019;29:2579-2589.e4 pubmed publisher |
Zhang S, Feng S, Jiang W, Huang X, Chen J. Construction and optimization of a base editor based on the MS2 system. Animal Model Exp Med. 2019;2:185-190 pubmed publisher |
Chen B, Gu P, Jia J, Liu W, Liu Y, Liu W, et al. Optimization Strategy for Generating Gene-edited Tibet Minipigs by Synchronized Oestrus and Cytoplasmic Microinjection. Int J Biol Sci. 2019;15:2719-2732 pubmed publisher |
Hua R, Wei H, Liu C, Zhang Y, Liu S, Guo Y, et al. FBXO47 regulates telomere-inner nuclear envelope integration by stabilizing TRF2 during meiosis. Nucleic Acids Res. 2019;47:11755-11770 pubmed publisher |
Xiong Z, Xia P, Zhu X, Geng J, Wang S, Ye B, et al. Glutamylation of deubiquitinase BAP1 controls self-renewal of hematopoietic stem cells and hematopoiesis. J Exp Med. 2020;217: pubmed publisher |
Rong Y, Ji S, Zhu Y, Wu Y, Shen L, Fan H. ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation. Nucleic Acids Res. 2019;47:11387-11402 pubmed publisher |
Singh P, Patel R, Palmer N, Grenier J, Paduch D, Kaldis P, et al. CDK2 kinase activity is a regulator of male germ cell fate. Development. 2019;146: pubmed publisher |
Feng W, Simpson D, Carvajal Garcia J, Price B, Kumar R, Mose L, et al. Genetic determinants of cellular addiction to DNA polymerase theta. Nat Commun. 2019;10:4286 pubmed publisher |
Kumita W, Sato K, Suzuki Y, Kurotaki Y, Harada T, Zhou Y, et al. Efficient generation of Knock-in/Knock-out marmoset embryo via CRISPR/Cas9 gene editing. Sci Rep. 2019;9:12719 pubmed publisher |
Tsai S, Huang P, Tsai H, Hsu Y, Chen Y, Wang J, et al. Roles of the hypoximir microRNA-424/322 in acute hypoxia and hypoxia-induced pulmonary vascular leakage. FASEB J. 2019;33:12565-12575 pubmed publisher |
Gómez H L, Felipe Medina N, Condezo Y, García Valiente R, Ramos I, Suja J, et al. The PSMA8 subunit of the spermatoproteasome is essential for proper meiotic exit and mouse fertility. PLoS Genet. 2019;15:e1008316 pubmed publisher |
Liu L, Lu J, Li F, Xing X, Li T, Yang X, et al. IDH1 fine-tunes cap-dependent translation initiation. J Mol Cell Biol. 2019;11:816-828 pubmed publisher |
Wang D, Zheng X, Fu B, Nian Z, Qian Y, Sun R, et al. Hepatectomy promotes recurrence of liver cancer by enhancing IL-11-STAT3 signaling. EBioMedicine. 2019;46:119-132 pubmed publisher |
Liu G, Wang Y, Zheng W, Cheng H, Zhou R. P11 Loss-of-Function is Associated with Decreased Cell Proliferation and Neurobehavioral Disorders in Mice. Int J Biol Sci. 2019;15:1383-1395 pubmed publisher |
Yu X, Qiu W, Yang L, Zhang Y, He M, Li L, et al. Defining multistep cell fate decision pathways during pancreatic development at single-cell resolution. EMBO J. 2019;38: pubmed publisher |
Wang L, Sun Z, Xiang B, Wei C, Wang Y, Sun K, et al. Targeted deletion of Insm2 in mice result in reduced insulin secretion and glucose intolerance. J Transl Med. 2018;16:297 pubmed publisher |
Nacson J, Krais J, Bernhardy A, Clausen E, Feng W, Wang Y, et al. BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance. Cell Rep. 2018;24:3513-3527.e7 pubmed publisher |
Zeng Y, Li J, Li G, Huang S, Yu W, Zhang Y, et al. Correction of the Marfan Syndrome Pathogenic FBN1 Mutation by Base Editing in Human Cells and Heterozygous Embryos. Mol Ther. 2018;26:2631-2637 pubmed publisher |
Bai S, Fu K, Yin H, Cui Y, Yue Q, Li W, et al. Sox30 initiates transcription of haploid genes during late meiosis and spermiogenesis in mouse testes. Development. 2018;145: pubmed publisher |
Zhao Y, Wang X, Wang Q, Deng Y, Li K, Zhang M, et al. USP2a Supports Metastasis by Tuning TGF-β Signaling. Cell Rep. 2018;22:2442-2454 pubmed publisher |
Yu H, Long W, Zhang X, Xu K, Guo J, Zhao H, et al. Generation of GHR-modified pigs as Laron syndrome models via a dual-sgRNAs/Cas9 system and somatic cell nuclear transfer. J Transl Med. 2018;16:41 pubmed publisher |
Cui Y, Niu Y, Zhou J, Chen Y, Cheng Y, Li S, et al. Generation of a precise Oct4-hrGFP knockin cynomolgus monkey model via CRISPR/Cas9-assisted homologous recombination. Cell Res. 2018;28:383-386 pubmed publisher |
Lei L, Chen H, Xue W, Yang B, Hu B, Wei J, et al. APOBEC3 induces mutations during repair of CRISPR-Cas9-generated DNA breaks. Nat Struct Mol Biol. 2018;25:45-52 pubmed publisher |
Deng Y, Cai Z, Shi S, Jiang H, Shang Y, Ma N, et al. Cilia loss sensitizes cells to transformation by activating the mevalonate pathway. J Exp Med. 2018;215:177-195 pubmed publisher |
Zhao C, Zheng X, Qu W, Li G, Li X, Miao Y, et al. CRISPR-offinder: a CRISPR guide RNA design and off-target searching tool for user-defined protospacer adjacent motif. Int J Biol Sci. 2017;13:1470-1478 pubmed publisher |
Xu M, Xu H, Chen J, Chen C, Xu F, Qin Z. Generation of conditional Acvrl1 knockout mice by CRISPR/Cas9-mediated gene targeting. Mol Cell Probes. 2018;37:32-38 pubmed publisher |
Pan L, Sheng M, Huang Z, Zhu Z, Xu C, Teng L, et al. Zinc-finger protein 418 overexpression protects against cardiac hypertrophy and fibrosis. PLoS ONE. 2017;12:e0186635 pubmed publisher |
Tan G, Liu Y, Wang L, Li K, Zhang Z, Li H, et al. PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by regulating synaptic transmission in cerebellum. Cell Res. 2018;28:90-110 pubmed publisher |
Chen X, Zhou L, Peng N, Yu H, Li M, Cao Z, et al. MicroRNA-302a suppresses influenza A virus-stimulated interferon regulatory factor-5 expression and cytokine storm induction. J Biol Chem. 2017;292:21291-21303 pubmed publisher |
Shao J, Xu Q, Su S, Meng F, Zou Z, Chen F, et al. Engineered cells for costimulatory enhancement combined with IL-21 enhance the generation of PD-1-disrupted CTLs for adoptive immunotherapy. Cell Immunol. 2017;320:38-45 pubmed publisher |
Conlin M, Reid D, Small G, Chang H, Watanabe G, Lieber M, et al. DNA Ligase IV Guides End-Processing Choice during Nonhomologous End Joining. Cell Rep. 2017;20:2810-2819 pubmed publisher |
Ma Y, Zhang L, Huang X. Building Cre Knockin Rat Lines Using CRISPR/Cas9. Methods Mol Biol. 2017;1642:37-52 pubmed publisher |
Hsu P, Zhu Y, Ma H, Guo Y, Shi X, Liu Y, et al. Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis. Cell Res. 2017;27:1115-1127 pubmed publisher |
Tang T, Lang X, Xu C, Wang X, Gong T, Yang Y, et al. CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation. Nat Commun. 2017;8:202 pubmed publisher |
Xu J, Xu X, Wang B, Ma Y, Zhang L, Xu H, et al. Nuclear carbonic anhydrase 6B associates with PRMT5 to epigenetically promote IL-12 expression in innate response. Proc Natl Acad Sci U S A. 2017;114:8620-8625 pubmed publisher |
Lu B, Ren Y, Sun X, Han C, Wang H, Chen Y, et al. Induction of INKIT by Viral Infection Negatively Regulates Antiviral Responses through Inhibiting Phosphorylation of p65 and IRF3. Cell Host Microbe. 2017;22:86-98.e4 pubmed publisher |
Niu Y, Zhao X, Zhou J, Li Y, Huang Y, Cai B, et al. Efficient generation of goats with defined point mutation (I397V) in GDF9 through CRISPR/Cas9. Reprod Fertil Dev. 2018;30:307-312 pubmed publisher |
Sun H, Zhang Q, Jing Y, Zhang M, Wang H, Cai Z, et al. USP13 negatively regulates antiviral responses by deubiquitinating STING. Nat Commun. 2017;8:15534 pubmed publisher |
Jiang L, Li T, Zhang X, Zhang B, Yu C, Li Y, et al. RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice. Curr Biol. 2017;27:1498-1505.e6 pubmed publisher |
Huang L, Hua Z, Xiao H, Cheng Y, Xu K, Gao Q, et al. CRISPR/Cas9-mediated ApoE-/- and LDLR-/- double gene knockout in pigs elevates serum LDL-C and TC levels. Oncotarget. 2017;8:37751-37760 pubmed publisher |
Yu C, Liang C, Li Y, Hu Q, Zheng W, Niu N, et al. ZNF307 (Zinc Finger Protein 307) Acts as a Negative Regulator of Pressure Overload-Induced Cardiac Hypertrophy. Hypertension. 2017;69:615-624 pubmed publisher |
Su S, Zou Z, Chen F, Ding N, Du J, Shao J, et al. CRISPR-Cas9-mediated disruption of PD-1 on human T cells for adoptive cellular therapies of EBV positive gastric cancer. Oncoimmunology. 2017;6:e1249558 pubmed publisher |
Fu X, Zhang L, Jin Y, Sun X, Zhang A, Wen Z, et al. Loss of Myh14 Increases Susceptibility to Noise-Induced Hearing Loss in CBA/CaJ Mice. Neural Plast. 2016;2016:6720420 pubmed publisher |
Zhen S, Hua L, Liu Y, Sun X, Jiang M, Chen W, et al. Inhibition of long non-coding RNA UCA1 by CRISPR/Cas9 attenuated malignant phenotypes of bladder cancer. Oncotarget. 2017;8:9634-9646 pubmed publisher |
Li Z, Zhou C, Tan L, Chen P, Cao Y, Li C, et al. Variants of genes encoding collagens and matrix metalloproteinase system increased the risk of aortic dissection. Sci China Life Sci. 2017;60:57-65 pubmed publisher |
Lu Y, Xu D, Zhao Y, Zhu G, Zhu M, Liu W, et al. Smad Nuclear Interacting Protein 1 Acts as a Protective Regulator of Pressure Overload-Induced Pathological Cardiac Hypertrophy. J Am Heart Assoc. 2016;5: pubmed |
Zhen S, Lu J, Wang L, Sun X, Zhang J, Li X, et al. In Vitro and In Vivo Synergistic Therapeutic Effect of Cisplatin with Human Papillomavirus16 E6/E7 CRISPR/Cas9 on Cervical Cancer Cell Line. Transl Oncol. 2016;9:498-504 pubmed publisher |
Gómez H L, Felipe Medina N, Sanchez Martin M, Davies O, Ramos I, García Tuñón I, et al. C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility. Nat Commun. 2016;7:13298 pubmed publisher |
Li W, Zhao Y, Zhu G, Peng W, Zhu M, Yu X, et al. Dual specific phosphatase 12 ameliorates cardiac hypertrophy in response to pressure overload. Clin Sci (Lond). 2017;131:141-154 pubmed publisher |
Zhang T, Yin Y, Liu H, Du W, Ren C, Wang L, et al. Generation of VDR Knock-Out Mice via Zygote Injection of CRISPR/Cas9 System. PLoS ONE. 2016;11:e0163551 pubmed publisher |
Ying X, Zhao Y, Yao T, Yuan A, Xu L, Gao L, et al. Novel Protective Role for Ubiquitin-Specific Protease 18 in Pathological Cardiac Remodeling. Hypertension. 2016;68:1160-1170 pubmed |
Bevacqua R, Fernandez Martin R, Savy V, Canel N, Gismondi M, Kues W, et al. Efficient edition of the bovine PRNP prion gene in somatic cells and IVF embryos using the CRISPR/Cas9 system. Theriogenology. 2016;86:1886-1896.e1 pubmed publisher |
Wang X, Niu Y, Zhou J, Yu H, Kou Q, Lei A, et al. Multiplex gene editing via CRISPR/Cas9 exhibits desirable muscle hypertrophy without detectable off-target effects in sheep. Sci Rep. 2016;6:32271 pubmed publisher |
Baillat D, Russell W, Wagner E. CRISPR-Cas9 mediated genetic engineering for the purification of the endogenous integrator complex from mammalian cells. Protein Expr Purif. 2016;128:101-8 pubmed publisher |
Wojciechowska S, van Rooijen E, Ceol C, Patton E, White R. Generation and analysis of zebrafish melanoma models. Methods Cell Biol. 2016;134:531-49 pubmed publisher |
Li Y, Tang X, Li X, Dai H, Miao R, Cai J, et al. Regulator of G protein signalling 14 attenuates cardiac remodelling through the MEK-ERK1/2 signalling pathway. Basic Res Cardiol. 2016;111:47 pubmed publisher |
Dong Z, Huang M, Liu Z, Xie P, Dong Y, Wu X, et al. Focused screening of mitochondrial metabolism reveals a crucial role for a tumor suppressor Hbp1 in ovarian reserve. Cell Death Differ. 2016;23:1602-14 pubmed publisher |
Zhang L, Zhou J, Han J, Hu B, Hou N, Shi Y, et al. Generation of an Oocyte-Specific Cas9 Transgenic Mouse for Genome Editing. PLoS ONE. 2016;11:e0154364 pubmed publisher |
Huang J, Chen L, Yao Y, Tang C, Ding J, Fu C, et al. Pivotal Role of Regulator of G-protein Signaling 12 in Pathological Cardiac Hypertrophy. Hypertension. 2016;67:1228-36 pubmed publisher |
Yu C, Ji S, Sha Q, Dang Y, Zhou J, Zhang Y, et al. BTG4 is a meiotic cell cycle-coupled maternal-zygotic-transition licensing factor in oocytes. Nat Struct Mol Biol. 2016;23:387-94 pubmed publisher |
He B, Zhao Y, Gao L, Ying X, Xu L, Su Y, et al. Ubiquitin-Specific Protease 4 Is an Endogenous Negative Regulator of Pathological Cardiac Hypertrophy. Hypertension. 2016;67:1237-48 pubmed publisher |
Luo P, Wang P, Li Z, Zhang X, Jiang X, Gong J, et al. Hepatic Oncostatin M Receptor β Regulates Obesity-Induced Steatosis and Insulin Resistance. Am J Pathol. 2016;186:1278-92 pubmed publisher |
Li G, Ying L, Wang H, Wei S, Chen J, Chen Y, et al. Rac1b enhances cell survival through activation of the JNK2/c-JUN/Cyclin-D1 and AKT2/MCL1 pathways. Oncotarget. 2016;7:17970-85 pubmed publisher |
Li C, Zhou Q, Yang L, Chen Y, Hou J, Guo K, et al. Dual-specificity phosphatase 14 protects the heart from aortic banding-induced cardiac hypertrophy and dysfunction through inactivation of TAK1-P38MAPK/-JNK1/2 signaling pathway. Basic Res Cardiol. 2016;111:19 pubmed publisher |
Su S, Hu B, Shao J, Shen B, Du J, Du Y, et al. CRISPR-Cas9 mediated efficient PD-1 disruption on human primary T cells from cancer patients. Sci Rep. 2016;6:20070 pubmed publisher |
Yang L, Gao Z, Hu L, Wu G, Yang X, Zhang L, et al. Glycosylphosphatidylinositol Anchor Modification Machinery Deficiency Is Responsible for the Formation of Pro-Prion Protein (PrP) in BxPC-3 Protein and Increases Cancer Cell Motility. J Biol Chem. 2016;291:3905-17 pubmed publisher |
Miao R, Lu Y, Xing X, Li Y, Huang Z, Zhong H, et al. Regulator of G-Protein Signaling 10 Negatively Regulates Cardiac Remodeling by Blocking Mitogen-Activated Protein Kinase-Extracellular Signal-Regulated Protein Kinase 1/2 Signaling. Hypertension. 2016;67:86-98 pubmed publisher |
Bao D, Ma Y, Zhang X, Guan F, Chen W, Gao K, et al. Preliminary Characterization of a Leptin Receptor Knockout Rat Created by CRISPR/Cas9 System. Sci Rep. 2015;5:15942 pubmed publisher |
Zhou X, Wang L, Du Y, Xie F, Li L, Liu Y, et al. Efficient Generation of Gene-Modified Pigs Harboring Precise Orthologous Human Mutation via CRISPR/Cas9-Induced Homology-Directed Repair in Zygotes. Hum Mutat. 2016;37:110-8 pubmed publisher |
Wang X, Yu H, Lei A, Zhou J, Zeng W, Zhu H, et al. Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system. Sci Rep. 2015;5:13878 pubmed publisher |
Wang Y, Du Y, Shen B, Zhou X, Li J, Liu Y, et al. Efficient generation of gene-modified pigs via injection of zygote with Cas9/sgRNA. Sci Rep. 2015;5:8256 pubmed publisher |
Zhu X, Xu Y, Yu S, Lu L, Ding M, Cheng J, et al. An efficient genotyping method for genome-modified animals and human cells generated with CRISPR/Cas9 system. Sci Rep. 2014;4:6420 pubmed publisher |
Ma Y, Ma J, Zhang X, Chen W, Yu L, Lu Y, et al. Generation of eGFP and Cre knockin rats by CRISPR/Cas9. FEBS J. 2014;281:3779-90 pubmed publisher |
Ma Y, Shen B, Zhang X, Lu Y, Chen W, Ma J, et al. Heritable multiplex genetic engineering in rats using CRISPR/Cas9. PLoS ONE. 2014;9:e89413 pubmed publisher |
Shen B, Zhang W, Zhang J, Zhou J, Wang J, Chen L, et al. Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects. Nat Methods. 2014;11:399-402 pubmed publisher |
Zhou J, Wang J, Shen B, Chen L, Su Y, Yang J, et al. Dual sgRNAs facilitate CRISPR/Cas9-mediated mouse genome targeting. FEBS J. 2014;281:1717-25 pubmed publisher |
Niu Y, Shen B, Cui Y, Chen Y, Wang J, Wang L, et al. Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos. Cell. 2014;156:836-43 pubmed publisher |
Lu Y, Jiang T. Pseudovirus-based neuraminidase inhibition assays reveal potential H5N1 drug-resistant mutations. Protein Cell. 2013;4:356-63 pubmed publisher |
Shen B, Zhang J, Wu H, Wang J, Ma K, Li Z, et al. Generation of gene-modified mice via Cas9/RNA-mediated gene targeting. Cell Res. 2013;23:720-3 pubmed publisher |
