This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-MTS-CA-c-Src-FLAG
catalog :
44654
citations: 4
Reference
Chen F, Davies J, Calvo R, Chaudhari J, Dolios G, Taylor M, et al. Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction. iScience. 2022;25:104941 pubmed publisher
Lurette O, Guedouari H, Morris J, Martin Jimenez R, Robichaud J, Hamel Côté G, et al. Mitochondrial matrix-localized Src kinase regulates mitochondrial morphology. Cell Mol Life Sci. 2022;79:327 pubmed publisher
Lee Y, Choi J, Lee J, Shim D, Kim J, Park W, et al. TP53-dependence on the effect of doxorubicin and Src inhibitor combination therapy. Tumour Biol. 2018;40:1010428318794217 pubmed publisher
Ogura M, Yamaki J, Homma M, Homma Y. Mitochondrial c-Src regulates cell survival through phosphorylation of respiratory chain components. Biochem J. 2012;447:281-9 pubmed
product information
Catalog Number :
44654
Product Name :
pcDNA3-MTS-CA-c-Src-FLAG
article :
doi10.1042/BJ20120509
id6531
pubmed_id22823520
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_origin
backbone_size5500
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3Xho I
cloning_site_5Bgl II
promoterCMV promoter
sequencing_primer_3cgcctgtgcctagaggtt
sequencing_primer_5aaagccacttgcctaggga
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesASV, SRC1, THC6, c-SRC, p60-Src
geneSRC
id6714
genbank_ids
NM_005417
mutationchanged Tyr 530 to Phe
namev-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (SRC)
shRNA_sequence
size1608
species
9606
Homo sapiens
tags
locationN terminal on insert
tagmitochondria-targeting sequence (MTS: residues 1-40 of the amino acid sequence of very long chain acyl-CoA dehydrogenase)
locationC terminal on insert
tagFLAG tag
resistance markers :
1508
tags :
Unknown
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA