This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pGL4.75-KRAS LCS6m
catalog :
44571
citations: 4
Reference
Ferino A, Miglietta G, Picco R, Vogel S, Wengel J, Xodo L. MicroRNA therapeutics: design of single-stranded miR-216b mimics to target KRAS in pancreatic cancer cells. RNA Biol. 2018;15:1273-1285 pubmed publisher
Neu J, Dziunycz P, Dzung A, Lefort K, Falke M, Denzler R, et al. miR-181a decelerates proliferation in cutaneous squamous cell carcinoma by targeting the proto-oncogene KRAS. PLoS ONE. 2017;12:e0185028 pubmed publisher
Ling M, Huang P, Islam S, Heruth D, Li X, Zhang L, et al. Epigenetic regulation of Runx2 transcription and osteoblast differentiation by nicotinamide phosphoribosyltransferase. Cell Biosci. 2017;7:27 pubmed publisher
Kopp F, Wagner E, Roidl A. The proto-oncogene KRAS is targeted by miR-200c. Oncotarget. 2014;5:185-95 pubmed
product information
Catalog Number :
44571
Product Name :
pGL4.75-KRAS LCS6m
article :
doi
id6507
pubmed_id
bacterial resistance :
Ampicillin
cloning :
backbonepGL4.75
backbone_mutation
backbone_originPromega
backbone_size4281
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
A substitute for pGL3-KRAS LCS6m in Chin et al., 2008.
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3xba1
cloning_site_5Xba1
promoterCMV
sequencing_primer_3GCCTGAACTAGTTCACAGACAAGG
sequencing_primer_5TGACACAGGGAGACTACATTTAATTC
site_3_destroyed1
site_5_destroyed1
entrez_gene
aliases'C-K-RAS, C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, K-Ras, K-Ras 2, KI-RAS, KRAS1, KRAS2, NS, NS3, OES, RALD, RASK2, c-Ki-ras, c-Ki-ras2
geneKRAS
id3845
genbank_ids
NM_004985.3
mutationThe T allele at LCS6 (let-7 complementary site 6) was changed to the G allele (rs61764370 T>G)
nameKRAS 3'UTR
shRNA_sequence
size3900
species
9606
Homo sapiens
tags
resistance markers :
483
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA