MAVS-Pex | Addgene 44557 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

MAVS-Pex

catalog :

44557

citations: 3

Reference
Khantisitthiporn O, Shue B, Eyre N, Nash C, Turnbull L, Whitchurch C, et al. Viperin interacts with PEX19 to mediate peroxisomal augmentation of the innate antiviral response. Life Sci Alliance. 2021;4: pubmed publisher
Ding S, Zhu S, Ren L, Feng N, Song Y, Ge X, et al. Rotavirus VP3 targets MAVS for degradation to inhibit type III interferon expression in intestinal epithelial cells. elife. 2018;7: pubmed publisher
Dixit E, Boulant S, Zhang Y, Lee A, Odendall C, Shum B, et al. Peroxisomes are signaling platforms for antiviral innate immunity. Cell. 2010;141:668-81 pubmed publisher

product information

Catalog Number :

44557

Product Name :

MAVS-Pex

article :

doi	10.1016/j.cell.2010.04.018
id	4569
pubmed_id	20451243

bacterial resistance :

Ampicillin

cloning :

backbone

pMSCV2.2 IRES GFP

backbone_mutation

backbone_origin

backbone_size

6600

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

Retroviral

growth strain :

Retroviral vector for expression of a chimeric MAVS allele targeted to peroxisomes in mammalian cells

origin :

pi :

alt_names

cloning

clone_method	Restriction Enzyme
cloning_site_3	NotI
cloning_site_5	XhoI
promoter
sequencing_primer_3	MAVS scn
sequencing_primer_5	pMSCV forward
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	CARDIF, IPS-1, IPS1, VISA
gene	MAVS
id	57506

genbank_ids

BC044952 and AAH44952.1 for MAVS.

NM_002618 and NP_002609.1 for Pex13

mutation

contains aa1-500 of MAVS and aa136-233 of Pex13

name

MAVS-Pex13 chimeric protein

shRNA_sequence

size

1800

species

9606

Homo sapiens