This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pET-28a-hPKM1
catalog :
44241
citations: 6
Reference
Kim S, Wi J, Gwak H, Yang E, Kim S. Single-Cell FISH Analysis Reveals Distinct Shifts in PKM Isoform Populations during Drug Resistance Acquisition. Biomolecules. 2022;12: pubmed publisher
Xue Y, Wang S, Rana P, West E, Hong C, Feng H, et al. AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa. elife. 2021;10: pubmed publisher
Abeywardana T, Oh M, Jiang L, Yang Y, Kong M, Song J, et al. CARM1 suppresses de novo serine synthesis by promoting PKM2 activity. J Biol Chem. 2018;293:15290-15303 pubmed publisher
Shankar Babu M, Mahanta S, Lakhter A, Hato T, Paul S, Naidu S. Lapachol inhibits glycolysis in cancer cells by targeting pyruvate kinase M2. PLoS ONE. 2018;13:e0191419 pubmed publisher
Iansante V, Choy P, Fung S, Liu Y, Chai J, Dyson J, et al. PARP14 promotes the Warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation. Nat Commun. 2015;6:7882 pubmed publisher
Christofk H, Vander Heiden M, Wu N, Asara J, Cantley L. Pyruvate kinase M2 is a phosphotyrosine-binding protein. Nature. 2008;452:181-6 pubmed publisher
product information
Catalog Number :
44241
Product Name :
pET-28a-hPKM1
article :
doi10.1038/nature06667
id6455
pubmed_id18337815
bacterial resistance :
Kanamycin
cloning :
backbonepET-28a
backbone_mutation
backbone_originNovagen
backbone_size5400
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Bacterial Expression
origin :
37
pi :
alt_names
PKM1
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5EcoRI
promoterT7
sequencing_primer_3T7 Terminator Primer
sequencing_primer_5T7 Promoter Primer
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCTHBP, HEL-S-30, OIP3, PK3, PKM2, TCB, THBP1, p58
genePKM
id5315
genbank_ids
mutation
namePyruvate Kinase M1
shRNA_sequence
size1700
species
9606
Homo sapiens
tags
locationN terminal on backbone
tag6xHis
resistance markers :
64
1491
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA