pBMNZ-neo-Flag-TNFR1 L380A | Addgene 43949 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pBMNZ-neo-Flag-TNFR1 L380A

catalog :

43949

citations: 2

Reference
Egusquiaguirre S, Yeh J, Walker S, Liu S, Frank D. The STAT3 Target Gene TNFRSF1A Modulates the NF-κB Pathway in Breast Cancer Cells. Neoplasia. 2018;20:489-498 pubmed publisher
D Alessio A, Kluger M, Li J, Al Lamki R, Bradley J, Pober J. Targeting of tumor necrosis factor receptor 1 to low density plasma membrane domains in human endothelial cells. J Biol Chem. 2010;285:23868-79 pubmed publisher

product information

Catalog Number :

43949

Product Name :

pBMNZ-neo-Flag-TNFR1 L380A

article :

doi	10.1074/jbc.M110.122853
id	6394
pubmed_id	20511226

bacterial resistance :

Ampicillin

cloning :

backbone	pBMN-Z-IN
backbone_mutation
backbone_origin	Nolan Lab
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types

growth notes :

*The N-terminus not only has a Flag tag, but starting with methionine has a signal sequence that replaces the first 29 amino acids of the TNFR1 coding sequence: MGLSTVPDLLLPLVLLELLVGIYPSGVIG Downstream of the Flag tag, the coding sequence of this construct is a 100% match with the reference sequence NM_001065 except for the desirable L380A mutation that is already noted for this entry.

origin :

pi :

alt_names

TNFR1

cloning

entrez_gene

aliases	CD120a, FPF, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR55, TNFR60, p55, p55-R, p60
gene	TNFRSF1A
id	7132

genbank_ids

NM_001065

mutation

L380A

name

Tumor Necrosis Factor Receptor 1

shRNA_sequence

size

1374

species

9606

Homo sapiens