This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA6A-EGFR ICD (645-1186)
catalog :
42667
citations: 5
Reference
Papadakos K, Ekstr xf6 m A, Slipek P, Skourti E, Reid S, Pietras K, et al. Sushi domain-containing protein 4 binds to epithelial growth factor receptor and initiates autophagy in an EGFR phosphorylation independent manner. J Exp Clin Cancer Res. 2022;41:363 pubmed publisher
Gialeli C, Tuysuz E, Staaf J, Guleed S, Paciorek V, Morgelin M, et al. Complement inhibitor CSMD1 modulates epidermal growth factor receptor oncogenic signaling and sensitizes breast cancer cells to chemotherapy. J Exp Clin Cancer Res. 2021;40:258 pubmed publisher
Yammine L, Zablocki A, BARON W, Terzi F, Gallazzini M. Lipocalin-2 Regulates Epidermal Growth Factor Receptor Intracellular Trafficking. Cell Rep. 2019;29:2067-2077.e6 pubmed publisher
Al Akhrass H, Naves T, Vincent F, Magnaudeix A, Durand K, Bertin F, et al. Sortilin limits EGFR signaling by promoting its internalization in lung cancer. Nat Commun. 2017;8:1182 pubmed publisher
Hsu S, Hung M. Characterization of a novel tripartite nuclear localization sequence in the EGFR family. J Biol Chem. 2007;282:10432-40 pubmed
product information
Catalog Number :
42667
Product Name :
pcDNA6A-EGFR ICD (645-1186)
article :
doi10.1074/jbc.M610014200
id6303
pubmed_id17283074
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA6/myc-His A
backbone_mutation
backbone_originInvitrogen
backbone_size5100
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
epidermal growth factor receptor ICD (645-1186)
cloning
clone_methodRestriction Enzyme
cloning_site_3XbaI
cloning_site_5KpnI
promoter
sequencing_primer_3
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesERBB, ERBB1, ERRP, HER1, NISBD2, PIG61, mENA
geneEGFR
id1956
genbank_ids
mutation
nameEGFR ICD (645-1186)
shRNA_sequence
size600
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagMyc
locationC terminal on backbone
tag6xHis
resistance markers :
215
tags :
Unknown
terms :
Blasticidin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA