This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3 c-SRC (WT)
catalog :
42202
citations: 11
Reference
Fu J, Li S, Ma H, Yang J, Pagnotti G, Brown L, et al. The checkpoint inhibitor PD-1H/VISTA controls osteoclast-mediated multiple myeloma bone disease. Nat Commun. 2023;14:4271 pubmed publisher
Motaln H, x10c er x10d ek U, Yamoah A, Tripathi P, Aronica E, Goswami A, et al. Abl kinase-mediated FUS Tyr526 phosphorylation alters nucleocytoplasmic FUS localization in FTLD-FUS. Brain. 2023;: pubmed publisher
Park J, Park G, Lee J, Park J, Kim S, Kim E, et al. ERK phosphorylation disrupts the intramolecular interaction of capicua to promote cytoplasmic translocation of capicua and tumor growth. Front Mol Biosci. 2022;9:1030725 pubmed publisher
Zheng L, Trease A, Katsurada K, Spagnol G, Li H, Shi W, et al. Inhibition of Pyk2 and Src activity improves Cx43 gap junction intercellular communication. J Mol Cell Cardiol. 2020;149:27-40 pubmed publisher
Carabias A, Gómez Hernández M, de Cima S, Rodríguez Blázquez A, Morán Vaquero A, Gonzalez Saenz P, et al. Mechanisms of autoregulation of C3G, activator of the GTPase Rap1, and its catalytic deregulation in lymphomas. Sci Signal. 2020;13: pubmed publisher
Du Q, Wang W, Liu T, Shang C, Huang J, Liao Y, et al. High Expression of Integrin α3 Predicts Poor Prognosis and Promotes Tumor Metastasis and Angiogenesis by Activating the c-Src/Extracellular Signal-Regulated Protein Kinase/Focal Adhesion Kinase Signaling Pathway in Cervical Cancer. Front Oncol. 2020;10:36 pubmed publisher
Bunda S, Heir P, Li A, Mamatjan Y, Zadeh G, Aldape K. c-Src Phosphorylates and Inhibits the Function of the CIC Tumor Suppressor Protein. Mol Cancer Res. 2020;18:774-786 pubmed publisher
Pal R, Palmieri M, Chaudhury A, Klisch T, di Ronza A, Neilson J, et al. Src regulates amino acid-mediated mTORC1 activation by disrupting GATOR1-Rag GTPase interaction. Nat Commun. 2018;9:4351 pubmed publisher
Lee N, Choi J, Yoon I, Lee J, Inn K. Positive regulatory role of c-Src-mediated TRIM25 tyrosine phosphorylation on RIG-I ubiquitination and RIG-I-mediated antiviral signaling pathway. Cell Immunol. 2018;332:94-100 pubmed publisher
Umaña A, Iwahori S, Kalejta R. Direct Substrate Identification with an Analog Sensitive (AS) Viral Cyclin-Dependent Kinase (v-Cdk). ACS Chem Biol. 2018;13:189-199 pubmed publisher
Luttrell L, Ferguson S, Daaka Y, Miller W, Maudsley S, Della Rocca G, et al. Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. Science. 1999;283:655-61 pubmed
product information
Catalog Number :
42202
Product Name :
pcDNA3 c-SRC (WT)
article :
doi10.1126/science.283.5402.655
id1329
pubmed_id9924018
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5446
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
A 1.3kb HindIII-BamHI fragment and a 0.3kb BamHI-NotI fragment were subcloned from pBS/KS c-SRC into pcDNA3 via HindIII/NotI
origin :
37
pi :
alt_names
SRC
sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
p60-Src
cloning
clone_methodRestriction Enzyme
cloning_site_3NotI
cloning_site_5HindIII
promoterCMV
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesASV, SRC1, THC6, c-SRC, p60-Src
geneSRC
id6714
genbank_ids
NM_005417.3
AAA60584.1
mutationL176F mutation compared to reference sequence NM_005417.3. See c-SRC supplementary sequence information file for more details
namec-SRC
shRNA_sequence
size1600
species
9606
Homo sapiens
tags
resistance markers :
285
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA