This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-GFP-IMP2-2
catalog :
42175
citations: 4
Reference
Kendzia S, Franke S, Kr xf6 hler T, Golob Schwarzl N, Schweiger C, Toeglhofer A, et al. A combined computational and functional approach identifies IGF2BP2 as a driver of chemoresistance in a wide array of pre-clinical models of colorectal cancer. Mol Cancer. 2023;22:89 pubmed publisher
Qian B, Wang P, Zhang D, Wu L. m6A modification promotes miR-133a repression during cardiac development and hypertrophy via IGF2BP2. Cell Death Discov. 2021;7:157 pubmed publisher
Kessler S, Laggai S, Barghash A, Schultheiss C, Lederer E, Artl M, et al. IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype. Cell Death Dis. 2015;6:e1894 pubmed publisher
Kessler S, Pokorny J, Zimmer V, Laggai S, Lammert F, Bohle R, et al. IGF2 mRNA binding protein p62/IMP2-2 in hepatocellular carcinoma: antiapoptotic action is independent of IGF2/PI3K signaling. Am J Physiol Gastrointest Liver Physiol. 2013;304:G328-36 pubmed publisher
product information
Catalog Number :
42175
Product Name :
pcDNA3-GFP-IMP2-2
article :
doi10.1152/ajpgi.00005.2012
id6914
pubmed_id23257922
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3.1/CT-GFP TOPO
backbone_mutation
backbone_origininvitrogen
backbone_size6157
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
IMP2-2, p62, IGF2BP2-2
cloning
clone_methodTOPO Cloning
cloning_site_3
cloning_site_5
promoterT7
sequencing_primer_3GGGTAAGCTTTCCGTATGTAGC
sequencing_primer_5TAATACGACTCACTATAGGG
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesIMP-2, IMP2, VICKZ2
geneIGF2BP2
id10644
genbank_ids
NM_001007225.1
mutation
nameInsulin-like growth factor 2 mRNA binding protein 2-2
shRNA_sequence
size1671
species
9606
Homo sapiens
tags
locationC terminal on insert
tagGFP
resistance markers :
1423
tags :
Unknown
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA