This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCAGGS-Flag-hsDicer
catalog :
41584
citations: 15
Reference
Bidkhori H, Farshchian M, Hasanzadeh H, Jafarzadeh Esfehani R, Alsadat Mahmoudian R, Moradi Marjaneh M, et al. Unraveling The Effects of DICER1 Overexpression on Immune-Related Genes Expression in Mesenchymal Stromal/Stem Cells: Insights for Therapeutic Applications. Cell J. 2023;25:696-705 pubmed publisher
Torrez R, Nagaraja S, Menon A, Chang L, Ohi M, Garner A. Comparative Biochemical Studies of Disease-Associated Human Dicer Mutations on Processing of a Pre-microRNA and snoRNA. Biochemistry. 2023;62:1725-1734 pubmed publisher
Liu X, Yang Y, Wang Y. HSP90 and Aha1 modulate microRNA maturation through promoting the folding of Dicer1. Nucleic Acids Res. 2022;: pubmed publisher
Wang Q, Wang J, Xu Y, Li Z, Wang B, Li Y. The Interaction of Influenza A NS1 and Cellular TRBP Protein Modulates the Function of RNA Interference Machinery. Front Microbiol. 2022;13:859420 pubmed publisher
Zhang Y, Xu Y, Dai Y, Li Z, Wang J, Ye Z, et al. Efficient Dicer processing of virus-derived double-stranded RNAs and its modulation by RIG-I-like receptor LGP2. PLoS Pathog. 2021;17:e1009790 pubmed publisher
Luo Q, Zhang J, Li P, Wang Q, Zhang Y, Roy Chaudhuri B, et al. RNA structure probing reveals the structural basis of Dicer binding and cleavage. Nat Commun. 2021;12:3397 pubmed publisher
Wang S, Xu J, Guo Y, Cai Y, Ren X, Zhu W, et al. MicroRNA-497 Reduction and Increase of Its Family Member MicroRNA-424 Lead to Dysregulation of Multiple Inflammation Related Genes in Synovial Fibroblasts With Rheumatoid Arthritis. Front Immunol. 2021;12:619392 pubmed publisher
Copeland J, Simões Costa M. Post-transcriptional tuning of FGF signaling mediates neural crest induction. Proc Natl Acad Sci U S A. 2020;117:33305-33316 pubmed publisher
Nourse J, Braun J, Lackner K, Huttelmaier S, Danckwardt S. Large-scale identification of functional microRNA targeting reveals cooperative regulation of the hemostatic system. J Thromb Haemost. 2018;16:2233-2245 pubmed publisher
Yan H, Bhattarai U, Song Y, Liang F. Design, synthesis and activity of light deactivatable microRNA inhibitor. Bioorg Chem. 2018;80:492-497 pubmed publisher
Zhang M, Yang L, Yuan F, Chen Y, Lin G. Dicer inactivation stimulates limb regeneration ability in Xenopus laevis. Wound Repair Regen. 2018;26:46-53 pubmed publisher
van der Veen A, Maillard P, Schmidt J, Lee S, Deddouche Grass S, Borg A, et al. The RIG-I-like receptor LGP2 inhibits Dicer-dependent processing of long double-stranded RNA and blocks RNA interference in mammalian cells. EMBO J. 2018;37: pubmed publisher
Li Y, Basavappa M, Lu J, Dong S, Cronkite D, Prior J, et al. Induction and suppression of antiviral RNA interference by influenza A virus in mammalian cells. Nat Microbiol. 2016;2:16250 pubmed publisher
Maillard P, van der Veen A, Deddouche Grass S, Rogers N, Merits A, Reis E Sousa C. Inactivation of the type I interferon pathway reveals long double-stranded RNA-mediated RNA interference in mammalian cells. EMBO J. 2016;35:2505-2518 pubmed
Gurtan A, Lu V, Bhutkar A, Sharp P. In vivo structure-function analysis of human Dicer reveals directional processing of precursor miRNAs. RNA. 2012;18:1116-22 pubmed publisher
product information
Catalog Number :
41584
Product Name :
pCAGGS-Flag-hsDicer
article :
doi10.1261/rna.032680.112
id6060
pubmed_id22546613
bacterial resistance :
Ampicillin
cloning :
backbonepCAGGS
backbone_mutation
backbone_origin
backbone_size4790
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
Dicer1
cloning
clone_methodUnknown
cloning_site_3
cloning_site_5
promoterCMV
sequencing_primer_3Custom
sequencing_primer_5Custom
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesDCR1, Dicer, Dicer1e, GLOW, HERNA, K12H4.8-LIKE, MNG1, RMSE2, aviD
geneDICER1
id23405
genbank_ids
NM_177438
NM_030621
mutationNone
namehsDicer
shRNA_sequence
size5796
species
9606
Homo sapiens
tags
locationN terminal on insert
tagFlag
resistance markers :
461
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA