This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Mek2
catalog :
40776
citations: 3
Reference
Kent O, Saha M, Coyaud E, Burston H, Law N, Dadson K, et al. Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes. Nat Commun. 2020;11:4673 pubmed publisher
Hanrahan A, SYLVESTER B, Chang M, Elzein A, Gao J, Han W, et al. Leveraging systematic functional analysis to benchmark an in silico framework distinguishes driver from passenger MEK mutants in cancer. Cancer Res. 2020;: pubmed publisher
Banks A, McAllister F, Camporez J, Zushin P, Jurczak M, Laznik Bogoslavski D, et al. An ERK/Cdk5 axis controls the diabetogenic actions of PPARγ. Nature. 2015;517:391-5 pubmed publisher
product information
Catalog Number :
40776
Product Name :
Mek2
article :
doi
id5918
pubmed_id
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3.1-Hygro
backbone_mutation
backbone_origin
backbone_size5600
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodLigation Independent Cloning
cloning_site_3
cloning_site_5
promoterCMV
sequencing_primer_3BGH-rev
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCFC4, MAPKK2, MEK2, MKK2, PRKMK2
geneMAP2K2
id5605
genbank_ids
mutationStarting Met removed
nameMKK2
shRNA_sequence
size1200
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagMyc
resistance markers :
943
tags :
High Copy
terms :
Hygromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA