This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pMIEG3-c-Jun
catalog :
40348
citations: 11
Reference
Al Moussawi K, Chung K, Carroll T, Osterburg C, Smirnov A, Lotz R, et al. Mutant Ras and inflammation-driven skin tumorigenesis is suppressed via a JNK-iASPP-AP1 axis. Cell Rep. 2022;41:111503 pubmed publisher
Bhattacharya A, Fushimi A, Yamashita N, Hagiwara M, Morimoto Y, Rajabi H, et al. MUC1-C Dictates JUN and BAF-Mediated Chromatin Remodeling at Enhancer Signatures in Cancer Stem Cells. Mol Cancer Res. 2022;20:556-567 pubmed publisher
Arnett A, Moo K, Flynn K, Sundberg T, Johannessen L, Shamji A, et al. The Cyclin-Dependent Kinase 8 (CDK8) Inhibitor DCA Promotes a Tolerogenic Chemical Immunophenotype in CD4+ T Cells via a Novel CDK8-GATA3-FOXP3 Pathway. Mol Cell Biol. 2021;41:e0008521 pubmed publisher
Alonso Curbelo D, Ho Y, Burdziak C, Mååg J, Morris J, Chandwani R, et al. A gene-environment-induced epigenetic program initiates tumorigenesis. Nature. 2021;: pubmed publisher
Chung J, Kim K, An S, Lee S, Lim B, Kang S, et al. Coxsackievirus and adenovirus receptor mediates the responses of endothelial cells to fluid shear stress. Exp Mol Med. 2019;51:144 pubmed publisher
Lee J, Chung J, Kim K, An S, Kim M, Park J, et al. Fluid shear stress regulates the expression of Lectin-like oxidized low density lipoprotein receptor-1 via KLF2-AP-1 pathway depending on its intensity and pattern in endothelial cells. Atherosclerosis. 2018;270:76-88 pubmed publisher
Lin X, Wang H, Li Y, Yang J, Yang R, Wei D, et al. Functional characterization of CXCR4 in mediating the expression of protein C system in experimental ulcerative colitis. Am J Transl Res. 2017;9:4821-4835 pubmed
Lukey M, Greene K, Erickson J, Wilson K, Cerione R. The oncogenic transcription factor c-Jun regulates glutaminase expression and sensitizes cells to glutaminase-targeted therapy. Nat Commun. 2016;7:11321 pubmed publisher
Gurdziel K, Vogt K, Walton K, Schneider G, Gumucio D. Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun. Dev Dyn. 2016;245:614-26 pubmed publisher
Yi L, Li F, Yong Y, Jianting D, Liting Z, Xuansheng H, et al. Upregulation of sestrin-2 expression protects against endothelial toxicity of angiotensin II. Cell Biol Toxicol. 2014;30:147-56 pubmed publisher
Wang Z, Sato H, Kusam S, Sehra S, Toney L, Dent A. Regulation of IL-10 gene expression in Th2 cells by Jun proteins. J Immunol. 2005;174:2098-105 pubmed
product information
Catalog Number :
40348
Product Name :
pMIEG3-c-Jun
article :
doi
id5870
pubmed_id15699140
bacterial resistance :
Ampicillin
cloning :
backbonepMIEG3
backbone_mutation
backbone_originDavid A. Williams (PMID: 10961859)
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
growth notes :
The c-Jun- and JunB-expressing retroviruses were constructed by inserting c-Jun and JunB cDNAs into the retroviral vector pMIEG3 via NotI and XhoI sites.
origin :
37
pi :
alt_names
jun proto-oncogene
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5NotI
promoter
sequencing_primer_3IRES-R2 (gacggcaatatggtggaaa)
sequencing_primer_5pLXSN_5
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAP-1, AP1, c-Jun, cJUN, p39
geneJUN
id3725
genbank_ids
NM_002228.3
NP_002219.1
mutation
namec-Jun
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagIRES eGFP
resistance markers :
1357
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA