This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pHM6-Q74
catalog :
40264
citations: 5
Reference
Peinado J, Chaplot K, Jarvela T, Barbieri E, Shorter J, Lindberg I. Sequestration of TDP-43216-414 Aggregates by Cytoplasmic Expression of the proSAAS Chaperone. ACS Chem Neurosci. 2022;13:1651-1665 pubmed publisher
Chang C, Tsou S, Chen W, Ho Y, Hung H, Liu G, et al. miR-302 Attenuates Mutant Huntingtin-Induced Cytotoxicity through Restoration of Autophagy and Insulin Sensitivity. Int J Mol Sci. 2021;22: pubmed publisher
Aladdin A, Yao Y, Yang C, Kahlert G, Ghani M, Király N, et al. The Proteasome Activators Blm10/PA200 Enhance the Proteasomal Degradation of N-Terminal Huntingtin. Biomolecules. 2020;10: pubmed publisher
Oliverio R, Nguyen P, Kdeiss B, Ord S, Daniels A, Nikolaidis N. Functional characterization of natural variants found on the major stress inducible 70-kDa heat shock gene, HSPA1A, in humans. Biochem Biophys Res Commun. 2018;506:799-804 pubmed publisher
Narain Y, Wyttenbach A, Rankin J, Furlong R, Rubinsztein D. A molecular investigation of true dominance in Huntington's disease. J Med Genet. 1999;36:739-46 pubmed
product information
Catalog Number :
40264
Product Name :
pHM6-Q74
article :
doi10.1136/jmg.36.10.739
id5830
pubmed_id10528852
bacterial resistance :
Ampicillin
cloning :
backbonepHM6
backbone_mutation
backbone_originRoche
backbone_size5450
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
huntingtin
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5HindIII
promoterCMV
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesHD, IT15, LOMARS
geneHTT
id3064
genbank_ids
mutationexpanded poly-Q
nameHTT partial exon 1 Q74
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagHA
locationC terminal on backbone
tag6x His
resistance markers :
1372
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA