This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pHM6-Q23
catalog :
40263
citations: 6
Reference
Chang C, Tsou S, Chen W, Ho Y, Hung H, Liu G, et al. miR-302 Attenuates Mutant Huntingtin-Induced Cytotoxicity through Restoration of Autophagy and Insulin Sensitivity. Int J Mol Sci. 2021;22: pubmed publisher
Aladdin A, Yao Y, Yang C, Kahlert G, Ghani M, Király N, et al. The Proteasome Activators Blm10/PA200 Enhance the Proteasomal Degradation of N-Terminal Huntingtin. Biomolecules. 2020;10: pubmed publisher
Pierzynowska K, Gaffke L, Hać A, Mantej J, Niedziałek N, Brokowska J, et al. Correction of Huntington's Disease Phenotype by Genistein-Induced Autophagy in the Cellular Model. Neuromolecular Med. 2018;20:112-123 pubmed publisher
Tanji K, Mori F, Miki Y, Utsumi J, Sasaki H, Kakita A, et al. YOD1 attenuates neurogenic proteotoxicity through its deubiquitinating activity. Neurobiol Dis. 2018;112:14-23 pubmed publisher
Tanji K, Miki Y, Maruyama A, Mori F, Mimura J, Itoh K, et al. The role of NUB1 in α-synuclein degradation in Lewy body disease model mice. Biochem Biophys Res Commun. 2016;470:635-642 pubmed publisher
Narain Y, Wyttenbach A, Rankin J, Furlong R, Rubinsztein D. A molecular investigation of true dominance in Huntington's disease. J Med Genet. 1999;36:739-46 pubmed
product information
Catalog Number :
40263
Product Name :
pHM6-Q23
article :
doi10.1136/jmg.36.10.739
id5830
pubmed_id10528852
bacterial resistance :
Ampicillin
cloning :
backbonepHM6
backbone_mutation
backbone_originRoche
backbone_size5450
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
huntingtin
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5HindIII
promoterCMV
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesHD, IT15, LOMARS
geneHTT
id3064
genbank_ids
mutationexpanded poly-Q
nameHTT partial exon 1 Q23
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagHA
locationC terminal on backbone
tag6x His
resistance markers :
1372
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA