| Reference |
|---|
Mansky R, Greguske E, Yu D, Zarate N, Intihar T, Tsai W, et al. Tumor suppressor p53 regulates heat shock factor 1 protein degradation in Huntington's disease. Cell Rep. 2023;42:112198 pubmed publisher
|
Ahat E, Bui S, Zhang J, da Veiga Leprevost F, Sharkey L, Reid W, et al. GRASP55 regulates the unconventional secretion and aggregation of mutant huntingtin. J Biol Chem. 2022;:102219 pubmed publisher
|
Watabe K, Niida Kawaguchi M, Tada M, Kato Y, Murata M, Tanji K, et al. Praja1 RING-finger E3 ubiquitin ligase is a common suppressor of neurodegenerative disease-associated protein aggregation. Neuropathology. 2022;: pubmed publisher
|
Palminha N, dos Santos Souza C, Griffin J, Liao C, Ferraiuolo L, El Khamisy S. Defective repair of topoisomerase I induced chromosomal damage in Huntington's disease. Cell Mol Life Sci. 2022;79:160 pubmed publisher
|
de Armas Rillo S, Fumagallo Reading F, Luis Ravelo D, Abdul Jalbar B, Gonzalez Hernandez T, Lahoz F. Random Lasing Detection of Mutant Huntingtin Expression in Cells. Sensors (Basel). 2021;21: pubmed publisher
|
Kim Guisbert K, Mossiah I, Guisbert E. Titration of SF3B1 Activity Reveals Distinct Effects on the Transcriptome and Cell Physiology. Int J Mol Sci. 2020;21: pubmed publisher
|
Sarraf S, Shah H, Kanfer G, Pickrell A, Holtzclaw L, Ward M, et al. Loss of TAX1BP1-Directed Autophagy Results in Protein Aggregate Accumulation in the Brain. Mol Cell. 2020;80:779-795.e10 pubmed publisher
|
Aravindan S, Chen S, Choudhry H, Molfetta C, Chen K, Liu A. Osmolytes dynamically regulate mutant Huntingtin aggregation and CREB function in Huntington's disease cell models. Sci Rep. 2020;10:15511 pubmed publisher
|
Glaser T, Shimojo H, Ribeiro D, Martins P, Beco R, Kosinski M, et al. ATP and spontaneous calcium oscillations control neural stem cell fate determination in Huntington's disease: a novel approach for cell clock research. Mol Psychiatry. 2020;: pubmed publisher
|
Pinho B, Reis S, Hartley R, Murphy M, Oliveira J. Mitochondrial superoxide generation induces a parkinsonian phenotype in zebrafish and huntingtin aggregation in human cells. Free Radic Biol Med. 2019;130:318-327 pubmed publisher
|
Chang C, Lin T, Ho H, Kuo C, Li H, Korolenko T, et al. GLP-1 Analogue Liraglutide Attenuates Mutant Huntingtin-Induced Neurotoxicity by Restoration of Neuronal Insulin Signaling. Int J Mol Sci. 2018;19: pubmed publisher
|
Chen J, Parekh M, Seliman H, Bakshinskaya D, Dai W, Kwan K, et al. Heat shock promotes inclusion body formation of mutant huntingtin (mHtt) and alleviates mHtt-induced transcription factor dysfunction. J Biol Chem. 2018;293:15581-15593 pubmed publisher
|
Zeng Y, Jones A, Thomas E, Nassif B, Silberg J, Segatori L. A Split Transcriptional Repressor That Links Protein Solubility to an Orthogonal Genetic Circuit. ACS Synth Biol. 2018;7:2126-2138 pubmed publisher
|
Victor M, Richner M, Olsen H, Lee S, Monteys A, Ma C, et al. Striatal neurons directly converted from Huntington's disease patient fibroblasts recapitulate age-associated disease phenotypes. Nat Neurosci. 2018;21:341-352 pubmed publisher
|
Al Ramahi I, Giridharan S, Chen Y, Patnaik S, Safren N, Hasegawa J, et al. Inhibition of PIP4K? ameliorates the pathological effects of mutant huntingtin protein. elife. 2017;6: pubmed publisher
|
Clift D, McEwan W, Labzin L, Konieczny V, Mogessie B, James L, et al. A Method for the Acute and Rapid Degradation of Endogenous Proteins. Cell. 2017;171:1692-1706.e18 pubmed publisher
|
Narain Y, Wyttenbach A, Rankin J, Furlong R, Rubinsztein D. A molecular investigation of true dominance in Huntington's disease. J Med Genet. 1999;36:739-46 pubmed
|