This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pMXs-IP HA-Parkin
catalog :
38248
citations: 12
Reference
Kocaturk N, Peker N, Eberhart K, Akkoç Y, Deveci G, Dengjel J, et al. Novel protein complexes containing autophagy and UPS components regulate proteasome-dependent PARK2 recruitment onto mitochondria and PARK2-PARK6 activity during mitophagy. Cell Death Dis. 2022;13:947 pubmed publisher
Kapadia B, Roychowdhury A, Kayastha F, Nanaji N, Gartenhaus R. PARK2 regulates eIF4B-driven lymphomagenesis. Mol Cancer Res. 2022;: pubmed publisher
Kruppa A, Kishi Itakura C, Masters T, Rorbach J, Grice G, Kendrick Jones J, et al. Myosin VI-Dependent Actin Cages Encapsulate Parkin-Positive Damaged Mitochondria. Dev Cell. 2018;44:484-499.e6 pubmed publisher
Xiao B, Deng X, Lim G, Xie S, Zhou Z, Lim K, et al. Superoxide drives progression of Parkin/PINK1-dependent mitophagy following translocation of Parkin to mitochondria. Cell Death Dis. 2017;8:e3097 pubmed publisher
Bartolomé A, García Aguilar A, Asahara S, Kido Y, Guillen C, Pajvani U, et al. MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling. Mol Cell Biol. 2017;37: pubmed publisher
Xiao B, Goh J, Xiao L, Xian H, Lim K, Liou Y. Reactive oxygen species trigger Parkin/PINK1 pathway-dependent mitophagy by inducing mitochondrial recruitment of Parkin. J Biol Chem. 2017;292:16697-16708 pubmed publisher
Xiao B, Deng X, Lim G, Zhou W, Saw W, Zhou Z, et al. p62-Mediated mitochondrial clustering attenuates apoptosis induced by mitochondrial depolarization. Biochim Biophys Acta Mol Cell Res. 2017;1864:1308-1317 pubmed publisher
Kishi Itakura C, Buss F. The Use of Correlative Light-Electron Microscopy (CLEM) to Study PINK1/Parkin-Mediated Mitophagy. Methods Mol Biol. 2018;1759:29-39 pubmed publisher
Wei Y, Chiang W, Sumpter R, Mishra P, Levine B. Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor. Cell. 2017;168:224-238.e10 pubmed publisher
Lee M, Sumpter R, Zou Z, Sirasanagandla S, Wei Y, Mishra P, et al. Peroxisomal protein PEX13 functions in selective autophagy. EMBO Rep. 2017;18:48-60 pubmed publisher
Lee S, She J, Deng B, Kim J, de Andrade M, Na J, et al. Multiple-level validation identifies PARK2 in the development of lung cancer and chronic obstructive pulmonary disease. Oncotarget. 2016;7:44211-44223 pubmed publisher
Yoshii S, Kishi C, Ishihara N, Mizushima N. Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane. J Biol Chem. 2011;286:19630-40 pubmed publisher
product information
Catalog Number :
38248
Product Name :
pMXs-IP HA-Parkin
article :
doi10.1074/jbc.M110.209338
id5628
pubmed_id21454557
bacterial resistance :
Ampicillin
cloning :
backbonepMXs-IP
backbone_mutation
backbone_originDr. Toshio Kitamura of the University of Tokyo
backbone_size5800
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
origin :
37
pi :
LPRS2, PARK2, PDJgenePRKNid5071genbank_ids
NM_004562
mutationnameParkinshRNA_sequencesize1398species
9606
Homo sapiens
tags
locationN terminal on insert
tagHA

Enzymecloning_site_3<
/td>NotIcloning_s
ite_5NotIpro
motersequenc
ing_primer_3aaggaaaaaagcggccgc
ctacacgtcgaaccagtggtc
sequencing_primer_5aaggaaaaaag
cggccgcgtaccatggcttacccatacga
site_3_destroyed<
/tr>site_5_destroyedtd>entre
z_gene
r>
aliasesAR-JP,
alt_names
cloning
clone_methodRestriction
plasmid copy :
Drs.Noriyuki Matsuda & Keiji Tanaka (Tokyo Metropolitan Institute of Medical Science)
resistance markers :
644
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA