This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
LYN11-FRB-mcherry
catalog :
38004
citations: 9
Reference
Ikhlef S, Lipp N, Delfosse V, Fuggetta N, Bourguet W, Magdeleine M, et al. Functional analyses of phosphatidylserine/PI(4)P exchangers with diverse lipid species and membrane contexts reveal unanticipated rules on lipid transfer. BMC Biol. 2021;19:248 pubmed publisher
Schink K, Tan K, Spangenberg H, Martorana D, Sneeggen M, Stévenin V, et al. The phosphoinositide coincidence detector Phafin2 promotes macropinocytosis by coordinating actin organisation at forming macropinosomes. Nat Commun. 2021;12:6577 pubmed publisher
Ren C, Yuan Q, Braun M, Zhang X, Petri B, Zhang J, et al. Leukocyte Cytoskeleton Polarization Is Initiated by Plasma Membrane Curvature from Cell Attachment. Dev Cell. 2019;49:206-219.e7 pubmed publisher
Royal A, Tinker A, Harmer S. Phosphatidylinositol-4,5-bisphosphate is required for KCNQ1/KCNE1 channel function but not anterograde trafficking. PLoS ONE. 2017;12:e0186293 pubmed publisher
Ghai R, Du X, Wang H, Dong J, Ferguson C, Brown A, et al. ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane. Nat Commun. 2017;8:757 pubmed publisher
Son S, Moroney G, Butler P. ?1-Integrin-Mediated Adhesion Is Lipid-Bilayer Dependent. Biophys J. 2017;113:1080-1092 pubmed publisher
Masters T, Tumbarello D, Chibalina M, Buss F. MYO6 Regulates Spatial Organization of Signaling Endosomes Driving AKT Activation and Actin Dynamics. Cell Rep. 2017;19:2088-2101 pubmed publisher
Sengelaub C, Navrazhina K, Ross J, Halberg N, Tavazoie S. PTPRN2 and PLCβ1 promote metastatic breast cancer cell migration through PI(4,5)P2-dependent actin remodeling. EMBO J. 2016;35:62-76 pubmed publisher
Hammond G, Fischer M, Anderson K, Holdich J, Koteci A, Balla T, et al. PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identity. Science. 2012;337:727-30 pubmed publisher
product information
Catalog Number :
38004
Product Name :
LYN11-FRB-mcherry
article :
doi10.1126/science.1222483
id5600
pubmed_id22722250
bacterial resistance :
Kanamycin
cloning :
backbonepmCherry-N1
backbone_mutation
backbone_originCLONTECH
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
entrez_gene
aliasesJTK8, SAIDV, p53Lyn, p56Lyn
geneLYN
id4067
genbank_ids
NM_002350.3
mutation
nameLYN
shRNA_sequence
size33
species
9606
Homo sapiens
tags
alt_names
cloning
entrez_gene
aliasesFRAP, FRAP1, FRAP2, RAFT1, RAPT1, SKS
geneMTOR
id2475
genbank_ids
NM_004958.3
mutation
nameMTOR
shRNA_sequence
size276
species
9606
Homo sapiens
tags
locationC terminal on insert
tagmCherry
plasmid copy :
Tamas Balla
resistance markers :
220
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA