This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
PJ-INPP5E
catalog :
38001
citations: 10
Reference
Cohen H, Zomot E, Nataniel T, Militsin R, Palty R. The SOAR of STIM1 interacts with plasma membrane lipids to form ER-PM contact sites. Cell Rep. 2023;42:112238 pubmed publisher
Smulders L, Altman R, Briseno C, Saatchi A, Wallace L, AlSebaye M, et al. Phosphatidylinositol Monophosphates Regulate the Membrane Localization of HSPA1A, a Stress-Inducible 70-kDa Heat Shock Protein. Biomolecules. 2022;12: pubmed publisher
Braun C, Parks X, Qudsi H, Lopes C. Membrane pools of phosphatidylinositol-4-phosphate regulate KCNQ1/KCNE1 membrane expression. Commun Biol. 2021;4:1392 pubmed publisher
Ren C, Yuan Q, Braun M, Zhang X, Petri B, Zhang J, et al. Leukocyte Cytoskeleton Polarization Is Initiated by Plasma Membrane Curvature from Cell Attachment. Dev Cell. 2019;49:206-219.e7 pubmed publisher
Hayashi Y, Nemoto Sasaki Y, Matsumoto N, Hama K, Tanikawa T, Oka S, et al. Complex formation of sphingomyelin synthase 1 with glucosylceramide synthase increases sphingomyelin and decreases glucosylceramide levels. J Biol Chem. 2018;293:17505-17522 pubmed publisher
Royal A, Tinker A, Harmer S. Phosphatidylinositol-4,5-bisphosphate is required for KCNQ1/KCNE1 channel function but not anterograde trafficking. PLoS ONE. 2017;12:e0186293 pubmed publisher
Ghai R, Du X, Wang H, Dong J, Ferguson C, Brown A, et al. ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane. Nat Commun. 2017;8:757 pubmed publisher
Hirama T, Das R, Yang Y, Ferguson C, Won A, Yip C, et al. Phosphatidylserine dictates the assembly and dynamics of caveolae in the plasma membrane. J Biol Chem. 2017;292:14292-14307 pubmed publisher
Sengelaub C, Navrazhina K, Ross J, Halberg N, Tavazoie S. PTPRN2 and PLCβ1 promote metastatic breast cancer cell migration through PI(4,5)P2-dependent actin remodeling. EMBO J. 2016;35:62-76 pubmed publisher
Hammond G, Fischer M, Anderson K, Holdich J, Koteci A, Balla T, et al. PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identity. Science. 2012;337:727-30 pubmed publisher
product information
Catalog Number :
38001
Product Name :
PJ-INPP5E
article :
doi10.1126/science.1222483
id5600
pubmed_id22722250
bacterial resistance :
Kanamycin
cloning :
backbonepmRFP-C1
backbone_mutation
backbone_origin
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Compared to GenBank reference sequence NM_019892, the INPP5E insert in this plasmid contains a C641A mutation. Please see the full plasmid sequence for the most accurate information.
origin :
37
pi :
alt_names
cloning
entrez_gene
aliasesFKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE
geneFKBP1A
id2280
genbank_ids
NM_054014
mutation
nameFKBP1A
shRNA_sequence
size318
species
9606
Homo sapiens
tags
locationN terminal on insert
tagmRFP
alt_names
cloning
entrez_gene
aliasesYKL212W, RSD1
geneSAC1
id853668
genbank_ids
NM_001179777
mutationCys 779 mutated to Ser
nameSAC1
shRNA_sequence
size1545
species
4932
Saccharomyces cerevisiae
tags
alt_names
cloning
entrez_gene
aliasesCORS1, CPD4, JBTS1, MORMS, PPI5PIV, pharbin
geneINPP5E
id56623
genbank_ids
NM_019892
mutation
nameINPP5E
shRNA_sequence
size
species
9606
Homo sapiens
tags
plasmid copy :
Tamas Balla
resistance markers :
220
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA