This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pGEN-mSmo
catalog :
37673
citations: 5
Reference
Di Minin G, Holzner M, Grison A, Dumeau C, Chan W, Monfort A, et al. TMED2 binding restricts SMO to the ER and Golgi compartments. PLoS Biol. 2022;20:e3001596 pubmed publisher
Ngo T, Wilkins B, So S, Keov P, Chahal K, Finch A, et al. Orphan receptor GPR37L1 remains unliganded. Nat Chem Biol. 2021;17:383-386 pubmed publisher
Chahal K, Li J, Kufareva I, Parle M, Durden D, Wechsler Reya R, et al. Nilotinib, an approved leukemia drug, inhibits smoothened signaling in Hedgehog-dependent medulloblastoma. PLoS ONE. 2019;14:e0214901 pubmed publisher
Lee Y, Patil S, Golz C, Strohmann C, Ziegler S, Kumar K, et al. A ligand-directed divergent catalytic approach to establish structural and functional scaffold diversity. Nat Commun. 2017;8:14043 pubmed publisher
Taipale J, Chen J, Cooper M, Wang B, Mann R, Milenkovic L, et al. Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine. Nature. 2000;406:1005-9 pubmed
product information
Catalog Number :
37673
Product Name :
pGEN-mSmo
article :
doi10.1038/35023008
id5540
pubmed_id10984056
bacterial resistance :
Kanamycin
cloning :
backbonepEG
backbone_mutationEGFP removed from pEGFP-C1
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3unknown
cloning_site_5unknown
promoterCMV
sequencing_primer_3SV40pA-R
sequencing_primer_5CMV-Fwd
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesE130215L21Rik, Smoh, bnb, smoothened
geneSmo
id319757
genbank_ids
mutation
nameSmo
shRNA_sequence
size
species
10090
Mus musculus
tags
resistance markers :
756
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA