This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pMDR1-1202
catalog :
37627
citations: 5
Reference
Dahlmann M, Werner R, Kortüm B, Kobelt D, Walther W, Stein U. Restoring Treatment Response in Colorectal Cancer Cells by Targeting MACC1-Dependent ABCB1 Expression in Combination Therapy. Front Oncol. 2020;10:599 pubmed publisher
Zhan Y, Qiu Y, Wang H, Wang Z, Xu J, Fan G, et al. Bufalin reverses multidrug resistance by regulating stemness through the CD133/nuclear factor-κB/MDR1 pathway in colorectal cancer. Cancer Sci. 2020;111:1619-1630 pubmed publisher
Deng L, Li Q, Lin G, Huang D, Zeng X, Wang X, et al. P-glycoprotein Mediates Postoperative Peritoneal Adhesion Formation by Enhancing Phosphorylation of the Chloride Channel-3. Theranostics. 2016;6:204-18 pubmed publisher
Choi Y, Cho S, Choi H, Woo S, Yun Y, Shin Y, et al. JNK1/2 Activation by an Extract from the Roots of Morus alba L. Reduces the Viability of Multidrug-Resistant MCF-7/Dox Cells by Inhibiting YB-1-Dependent MDR1 Expression. Evid Based Complement Alternat Med. 2013;2013:741985 pubmed publisher
Hu Z, Jin S, Scotto K. Transcriptional activation of the MDR1 gene by UV irradiation. Role of NF-Y and Sp1. J Biol Chem. 2000;275:2979-85 pubmed
product information
Catalog Number :
37627
Product Name :
pMDR1-1202
article :
doi10.1074/jbc.275.4.2979
id5532
pubmed_id10644769
bacterial resistance :
Ampicillin
cloning :
backbonepGL2 Basic
backbone_mutation
backbone_originPromega
backbone_size5598
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Luciferase
growth notes :
Please note that this plasmid forms dimers (see diagnostic digest linked above).
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3Nhe I
cloning_site_5Xma I
promoter
sequencing_primer_3GLprimer2
sequencing_primer_5GLprimer1
site_3_destroyed1
site_5_destroyed
entrez_gene
aliasesABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1, p-170
geneABCB1
id5243
genbank_ids
mutation
nameMDR1 promoter
shRNA_sequence
size1320
species
9606
Homo sapiens
tags
resistance markers :
1354
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA