pQCXIH-PSM-Rb | Addgene 37106 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pQCXIH-PSM-Rb

catalog :

37106

citations: 3

Reference
Yoshida A, Kitajima S, Li F, Cheng C, Takegami Y, Kohno S, et al. MicroRNA-140 mediates RB tumor suppressor function to control stem cell-like activity through interleukin-6. Oncotarget. 2017;8:13872-13885 pubmed publisher
Kruer T, Dougherty S, Reynolds L, Long E, De Silva T, Lockwood W, et al. Expression of the lncRNA Maternally Expressed Gene 3 (MEG3) Contributes to the Control of Lung Cancer Cell Proliferation by the Rb Pathway. PLoS ONE. 2016;11:e0166363 pubmed publisher
Angus S, Nevins J. A role for Mediator complex subunit MED13L in Rb/E2F-induced growth arrest. Oncogene. 2012;31:4709-17 pubmed publisher

product information

Catalog Number :

37106

Product Name :

pQCXIH-PSM-Rb

article :

doi	10.1038/onc.2011.622
id	5379
pubmed_id	22249253

bacterial resistance :

Ampicillin

cloning :

backbone

pQCXIH

backbone_mutation

backbone_origin

Clontech

backbone_size

7800

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

Retroviral

growth notes :

Also known as PSM.7LP (Knudsen and Wang 1997 MCB 17:5771).

origin :

pi :

alt_names

cloning

clone_method	Restriction Enzyme
cloning_site_3	BamHI
cloning_site_5	BamHI
promoter	CMV
sequencing_primer_3	IRES-R
sequencing_primer_5	LNCX
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	OSRC, PPP1R130, RB, p105-Rb, p110-RB1, pRb, pp110
gene	RB1
id	5925

genbank_ids

mutation

aa 379-928 only; large pocket of human Rb with aa substitutions S780A, S788D, S795A, S807A, S811L, T821A, T826A

name

shRNA_sequence

size

1600

species

9606

Homo sapiens