This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pLV-neo-CD2-FAK
catalog :
37013
citations: 5
Reference
Pollan S, Teng P, Jan Y, Livingstone J, Huang C, Kim M, et al. Loss of CDCP1 triggers FAK activation in detached prostate cancer cells. Am J Clin Exp Urol. 2021;9:350-366 pubmed
Hur Y, Feng S, Wilson K, Cerione R, Antonyak M. Embryonic Stem Cell-Derived Extracellular Vesicles Maintain ESC Stemness by Activating FAK. Dev Cell. 2021;56:277-291.e6 pubmed publisher
Troutman S, Moleirinho S, Kota S, NETTLES K, Fallahi M, Johnson G, et al. Crizotinib inhibits NF2-associated schwannoma through inhibition of focal adhesion kinase 1. Oncotarget. 2016;7:54515-54525 pubmed publisher
Nakasaki M, Hwang Y, Xie Y, Kataria S, Gund R, Hajam E, et al. The matrix protein Fibulin-5 is at the interface of tissue stiffness and inflammation in fibrosis. Nat Commun. 2015;6:8574 pubmed publisher
Shibue T, Weinberg R. Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs. Proc Natl Acad Sci U S A. 2009;106:10290-5 pubmed publisher
product information
Catalog Number :
37013
Product Name :
pLV-neo-CD2-FAK
article :
doi10.1073/pnas.0904227106
id5349
pubmed_id19502425
bacterial resistance :
Ampicillin
cloning :
backbonepLV-IRES-neo
backbone_mutationpLV-IRES-neo (a gift from I. Ben-Porath) was generated by replacing dsRed2 in pLV-tTRKRAB-Red (Addgene plasmid 12250) with the neomycin-resistance gene and removing the sequence of tTR-KRAB.
backbone_originI. Ben-Porath
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
origin :
37
pi :
alt_names
CD2
FAK
cloning
clone_methodUnknown
cloning_site_3
cloning_site_5
promoterEF1a
sequencing_primer_3WPRE-R
sequencing_primer_5EF1a-fwd
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesLFA-2, SRBC, T11
geneCD2
id914
aliasesFADK, FADK 1, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK
genePTK2
id5747
genbank_ids
mutation
nameCD2-FAK
shRNA_sequence
size
species
9606
Homo sapiens
tags
plasmid copy :
CD2-FAK was acquired from Dr. Steven Frisch (Frisch SM et al, 1996, JCB 134, 793).
resistance markers :
568
tags :
Unknown
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA