This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
NC16 pCDNA3.1 FLAG NRF2
catalog :
36971
citations: 21
Reference
Chen C, Chen M, Wen T, Anderson R, Cryns V. Regulation of NRF2 by Phosphoinositides and Small Heat Shock Proteins. bioRxiv. 2023;: pubmed publisher
De Angelis M, Anichini G, Palamara A, Nencioni L, Gori Savellini G. Dysregulation of intracellular redox homeostasis by the SARS-CoV-2 ORF6 protein. Virol J. 2023;20:239 pubmed publisher
Simon Molas H, Sánchez de Diego C, Navarro Sabate A, Castaño E, Ventura F, Bartrons R, et al. The Expression of TP53-Induced Glycolysis and Apoptosis Regulator (TIGAR) Can Be Controlled by the Antioxidant Orchestrator NRF2 in Human Carcinoma Cells. Int J Mol Sci. 2022;23: pubmed publisher
Walters T, McIntosh D, Ingram S, Tillery L, Motley E, Arinze I, et al. SUMO-Modification of Human Nrf2 at K110 and K533 Regulates Its Nucleocytoplasmic Localization, Stability and Transcriptional Activity. Cell Physiol Biochem. 2021;55:141-159 pubmed publisher
Ma L, Liu J, Lin Q, Gu Y, Yu W. Eugenol protects cells against oxidative stress via Nrf2. Exp Ther Med. 2021;21:107 pubmed publisher
Miller W, Sunilkumar S, Giordano J, Toro A, Barber A, Dennis M. The stress response protein REDD1 promotes diabetes-induced oxidative stress in the retina by Keap1-independent Nrf2 degradation. J Biol Chem. 2020;295:7350-7361 pubmed publisher
Sarcinelli C, Dragic H, Piecyk M, Barbet V, Duret C, Barthelaix A, et al. ATF4-Dependent NRF2 Transcriptional Regulation Promotes Antioxidant Protection during Endoplasmic Reticulum Stress. Cancers (Basel). 2020;12: pubmed publisher
Kim S, Piao S, Lee I, Nagar H, Choi S, Shin N, et al. CR6 interacting factor 1 deficiency induces premature senescence via SIRT3 inhibition in endothelial cells. Free Radic Biol Med. 2020;150:161-171 pubmed publisher
Ganner A, Pfeiffer Z, Wingendorf L, Kreis S, Klein M, Walz G, et al. The acetyltransferase p300 regulates NRF2 stability and localization. Biochem Biophys Res Commun. 2020;524:895-902 pubmed publisher
Matzinger M, Fischhuber K, Pölöske D, Mechtler K, Heiss E. AMPK leads to phosphorylation of the transcription factor Nrf2, tuning transactivation of selected target genes. Redox Biol. 2019;29:101393 pubmed publisher
Towers C, Fitzwalter B, Regan D, Goodspeed A, Morgan M, Liu C, et al. Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition. Dev Cell. 2019;50:690-703.e6 pubmed publisher
Paul S, Ghosh S, Mandal S, Sau S, Pal M. NRF2 transcriptionally activates the heat shock factor 1 promoter under oxidative stress and affects survival and migration potential of MCF7 cells. J Biol Chem. 2018;293:19303-19316 pubmed publisher
Jena K, Kolapalli S, Mehto S, Nath P, Das B, Sahoo P, et al. TRIM16 controls assembly and degradation of protein aggregates by modulating the p62-NRF2 axis and autophagy. EMBO J. 2018;37: pubmed publisher
Takahashi N, Chen H, Harris I, Stover D, Selfors L, Bronson R, et al. Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance. Cancer Cell. 2018;33:985-1003.e7 pubmed publisher
Skowron M, Niegisch G, Albrecht P, Van Koeveringe G, Romano A, Albers P, et al. Various Mechanisms Involve the Nuclear Factor (Erythroid-Derived 2)-Like (NRF2) to Achieve Cytoprotection in Long-Term Cisplatin-Treated Urothelial Carcinoma Cell Lines. Int J Mol Sci. 2017;18: pubmed publisher
Saidu N, Noé G, Cerles O, Cabel L, Kavian Tessler N, Chouzenoux S, et al. Dimethyl Fumarate Controls the NRF2/DJ-1 Axis in Cancer Cells: Therapeutic Applications. Mol Cancer Ther. 2017;16:529-539 pubmed publisher
Bendavit G, Aboulkassim T, Hilmi K, Shah S, Batist G. Nrf2 Transcription Factor Can Directly Regulate mTOR: LINKING CYTOPROTECTIVE GENE EXPRESSION TO A MAJOR METABOLIC REGULATOR THAT GENERATES REDOX ACTIVITY. J Biol Chem. 2016;291:25476-25488 pubmed
Gutsche K, Randi E, Blank V, Fink D, Wenger R, Leo C, et al. Intermittent hypoxia confers pro-metastatic gene expression selectively through NF-?B in inflammatory breast cancer cells. Free Radic Biol Med. 2016;101:129-142 pubmed publisher
Ahmad F, Dixit D, Sharma V, Kumar A, Joshi S, Sarkar C, et al. Nrf2-driven TERT regulates pentose phosphate pathway in glioblastoma. Cell Death Dis. 2016;7:e2213 pubmed publisher
Gupta A, Hossain M, Miller N, Kerin M, Callagy G, Gupta S. NCOA3 coactivator is a transcriptional target of XBP1 and regulates PERK-eIF2α-ATF4 signalling in breast cancer. Oncogene. 2016;35:5860-5871 pubmed publisher
Camp N, James R, Dawson D, Yan F, Davison J, Houck S, et al. Wilms tumor gene on X chromosome (WTX) inhibits degradation of NRF2 protein through competitive binding to KEAP1 protein. J Biol Chem. 2012;287:6539-50 pubmed publisher
product information
Catalog Number :
36971
Product Name :
NC16 pCDNA3.1 FLAG NRF2
article :
doi10.1074/jbc.M111.316471
id5336
pubmed_id22215675
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3.1
backbone_mutation
backbone_originInvitrogen
backbone_size5400
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3NotI
cloning_site_5AscI
promoterCMV
sequencing_primer_3BGH rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesHEBP1, IMDDHH, NRF2, Nrf-2
geneNFE2L2
id4780
genbank_ids
mutation
nameNRF2
shRNA_sequence
size1815
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagFlag
resistance markers :
348
tags :
High Copy
terms :
Zeocin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA