pEGFP.N1-HDAC6.DC (catalytic deficient) | Addgene 36189 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pEGFP.N1-HDAC6.DC (catalytic deficient)

catalog :

36189

citations: 3

Reference
Chiu Y, Medina C, Doyle C, Zhou M, Narahari A, Sandilos J, et al. Deacetylation as a receptor-regulated direct activation switch for pannexin channels. Nat Commun. 2021;12:4482 pubmed publisher
Liu J, Luan W, Zhang Y, Gu J, Shi Y, Yang Y, et al. HDAC6 interacts with PTPN1 to enhance melanoma cells progression. Biochem Biophys Res Commun. 2018;495:2630-2636 pubmed publisher
Gao Y, Hubbert C, Yao T. The microtubule-associated histone deacetylase 6 (HDAC6) regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation. J Biol Chem. 2010;285:11219-26 pubmed publisher

product information

Catalog Number :

36189

Product Name :

pEGFP.N1-HDAC6.DC (catalytic deficient)

article :

doi	10.1074/jbc.M109.042754
id	4274
pubmed_id	20133936

bacterial resistance :

Kanamycin

cloning :

backbone

pEGFP-N1

backbone_mutation

backbone_origin

Clontech

backbone_size

4700

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

growth notes :

Additional Reference: Gao etal Histone Deacetylase 6 Regulates Growth Factor-Induced Actin Remodeling and Endocytosis MOLECULAR AND CELLULAR BIOLOGY, Dec. 2007, p. 8637 8647

origin :

pi :

alt_names

cloning

clone_method	Restriction Enzyme
cloning_site_3	None
cloning_site_5	None
promoter	CMV
sequencing_primer_3	EGFP-N
sequencing_primer_5	CMV-Fwd
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	CPBHM, HD6, JM21, KDAC6, PPP1R90
gene	HDAC6
id	10013

genbank_ids

mutation

H216/611A

name

HDAC6.DC

shRNA_sequence

size

species

9606

Homo sapiens