This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pLenti-PGK-ER-KRAS(G12V)
catalog :
35635
citations: 5
Reference
Frey N, Tortola L, Egli D, Janjuha S, Rothgangl T, Marquart K, et al. Loss of Rnf31 and Vps4b sensitizes pancreatic cancer to T cell-mediated killing. Nat Commun. 2022;13:1804 pubmed publisher
Sturmlechner I, Zhang C, Sine C, van Deursen E, Jeganathan K, Hamada N, et al. p21 produces a bioactive secretome that places stressed cells under immunosurveillance. Science. 2021;374:eabb3420 pubmed publisher
Miyabayashi K, Baker L, Deschênes A, Traub B, Caligiuri G, Plenker D, et al. Intraductal Transplantation Models of Human Pancreatic Ductal Adenocarcinoma Reveal Progressive Transition of Molecular Subtypes. Cancer Discov. 2020;10:1566-1589 pubmed publisher
Guillon J, Petit C, Moreau M, Toutain B, Henry C, Roche H, et al. Regulation of senescence escape by TSP1 and CD47 following chemotherapy treatment. Cell Death Dis. 2019;10:199 pubmed publisher
Singh A, Sweeney M, Yu M, Burger A, Greninger P, Benes C, et al. TAK1 inhibition promotes apoptosis in KRAS-dependent colon cancers. Cell. 2012;148:639-50 pubmed publisher
product information
Catalog Number :
35635
Product Name :
pLenti-PGK-ER-KRAS(G12V)
article :
doi10.1016/j.cell.2011.12.033
id5156
pubmed_id22341439
bacterial resistance :
Ampicillin
cloning :
backbonepLenti-PGK-Hygro
backbone_mutation
backbone_originEric Campeau
backbone_size10000
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
origin :
37
pi :
alt_names
KRAS4B
cloning
clone_methodGateway Cloning
cloning_site_3
cloning_site_5
promoterPGK
sequencing_primer_3attL2
sequencing_primer_5attL1
site_3_destroyed
site_5_destroyed
entrez_gene
aliases'C-K-RAS, C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, K-Ras, K-Ras 2, KI-RAS, KRAS1, KRAS2, NS, NS3, OES, RALD, RASK2, c-Ki-ras, c-Ki-ras2
geneKRAS
id3845
genbank_ids
mutationGlycine 12 to Valine
nameK-Ras4B(G12V)
shRNA_sequence
size1100
species
9606
Homo sapiens
tags
locationN terminal on insert
tagER
resistance markers :
1194
tags :
High Copy
terms :
Hygromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA