This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pLenti 4.1 Ex miR200c-141
catalog :
35534
citations: 7
Reference
Simpson K, Watson K, Moorehead R. Elevated Expression of miR-200c/141 in MDA-MB-231 Cells Suppresses MXRA8 Levels and Impairs Breast Cancer Growth and Metastasis In Vivo. Genes (Basel). 2022;13: pubmed publisher
Zhang Y, He Y, Wu P, Hu S, Zhang Y, Chen C. miR-200c-141 Enhances Sheep Kidney Cell Reprogramming into Pluripotent Cells by Targeting ZEB1. Int J Stem Cells. 2021;14:423-433 pubmed publisher
Simpson K, Conquer van Heumen G, Watson K, Roth M, Martin C, Moorehead R. Re-expression of miR-200s in claudin-low mammary tumor cells alters cell shape and reduces proliferation and invasion potentially through modulating other miRNAs and SUZ12 regulated genes. Cancer Cell Int. 2021;21:89 pubmed publisher
Sciacovelli M, Gonçalves E, Johnson T, Zecchini V, da Costa A, Gaude E, et al. Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition. Nature. 2016;537:544-547 pubmed publisher
Bhatt S, Gupta M, Khamaisi M, Martinez R, Gritsenko M, Wagner B, et al. Preserved DNA Damage Checkpoint Pathway Protects against Complications in Long-Standing Type 1 Diabetes. Cell Metab. 2015;22:239-52 pubmed publisher
Li T, Lu H, Mukherjee D, Lahiri S, Shen C, Yu L, et al. Identification of epidermal growth factor receptor and its inhibitory microRNA141 as novel targets of Krüppel-like factor 8 in breast cancer. Oncotarget. 2015;6:21428-42 pubmed
Gregory P, Bert A, Paterson E, Barry S, Tsykin A, Farshid G, et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol. 2008;10:593-601 pubmed publisher
product information
Catalog Number :
35534
Product Name :
pLenti 4.1 Ex miR200c-141
article :
doi10.1038/ncb1722
id5145
pubmed_id18376396
bacterial resistance :
Ampicillin
cloning :
backbonepLenti 4.1Ex
backbone_mutation
backbone_originScott Hammond
backbone_size8749
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
growth strain :
3rd generation lentiviral vector
origin :
37
pi :
alt_names
MIRN200C
MIRN141
cloning
clone_methodRestriction Enzyme
cloning_site_3AvrII
cloning_site_5EcoRI
promoterCMV
sequencing_primer_3unknown
sequencing_primer_5Unknown
site_3_destroyed1
site_5_destroyed
entrez_gene
aliasesMIRN200C, mir-200c
geneMIR200C
id406985
aliasesMIRN141, mir-141
geneMIR141
id406933
genbank_ids
406985
406933
mutation
namemiR200c-141 genomic cluster
shRNA_sequence
size690
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagGFP
resistance markers :
1220
tags :
Unknown
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA