This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
GRK2-K220R
catalog :
35403
citations: 4
Reference
Rouault A, Buscaglia P, Sebag J. MRAP2 inhibits β-arrestin recruitment to the ghrelin receptor by preventing GHSR1a phosphorylation. J Biol Chem. 2022;298:102057 pubmed publisher
Mayberry C, Wilczek M, Fong T, Nichols S, Maginnis M. GRK2 mediates β-arrestin interactions with 5-HT2 receptors for JC polyomavirus endocytosis. J Virol. 2021;: pubmed publisher
Pack T, Orlen M, Ray C, Peterson S, Caron M. The dopamine D2 receptor can directly recruit and activate GRK2 without G protein activation. J Biol Chem. 2018;293:6161-6171 pubmed publisher
Freedman N, Liggett S, Drachman D, Pei G, Caron M, Lefkowitz R. Phosphorylation and desensitization of the human beta 1-adrenergic receptor. Involvement of G protein-coupled receptor kinases and cAMP-dependent protein kinase. J Biol Chem. 1995;270:17953-61 pubmed
product information
Catalog Number :
35403
Product Name :
GRK2-K220R
article :
doi10.1074/jbc.270.30.17953
id5123
pubmed_id7629102
bacterial resistance :
Ampicillin
cloning :
backbonepRK5
backbone_mutation
backbone_origin
backbone_size4754
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3HindIII
cloning_site_5HindIII
promoterCMV
sequencing_primer_3
sequencing_primer_5CMV-Fwd
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesADRBK1
geneGRK2
id282682
genbank_ids
mutationK220R
nameGRK2
shRNA_sequence
size3000
species
9913
Bos taurus
tags
resistance markers :
285
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA