This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
mCherry-Rab5CA(Q79L)
catalog :
35138
citations: 13
Reference
Bittel D, Jaiswal J. Early Endosomes Undergo Calcium-Triggered Exocytosis and Enable Repair of Diffuse and Focal Plasma Membrane Injury. Adv Sci (Weinh). 2023;10:e2300245 pubmed publisher
Mashimo M, Morozumi A, Nobeyama A, Kanzaki M, Negi S, Kato J, et al. Poly(ADP-ribose) Polymerase 1 Mediates Rab5 Inactivation after DNA Damage. Int J Mol Sci. 2022;23: pubmed publisher
Schmieder S, Tatituri R, Anderson M, Kelly K, Lencer W. Structural basis for acyl chain control over glycosphingolipid sorting and vesicular trafficking. Cell Rep. 2022;40:111063 pubmed publisher
Jeckel P, Kriebel M, Volkmer H. Autism Spectrum Disorder Risk Factor Met Regulates the Organization of Inhibitory Synapses. Front Mol Neurosci. 2021;14:659856 pubmed publisher
Hao M, Yeo S, Turner K, Harold A, Yang Y, Zhang X, et al. Autophagy Blockade Limits HER2+ Breast Cancer Tumorigenesis by Perturbing HER2 Trafficking and Promoting Release Via Small Extracellular Vesicles. Dev Cell. 2021;56:341-355.e5 pubmed publisher
Caudano F, Montalto G, Passalacqua M, Pronzato M, Fedele E, Ricciarelli R. cGMP favors the interaction between APP and BACE1 by inhibiting Rab5 GTPase activity. Sci Rep. 2020;10:1358 pubmed publisher
Leidal A, Huang H, Marsh T, Solvik T, Zhang D, Ye J, et al. The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles. Nat Cell Biol. 2020;22:187-199 pubmed publisher
Valenzuela J, Perez F. Localized Intercellular Transfer of Ephrin-As by Trans-endocytosis Enables Long-Term Signaling. Dev Cell. 2019;: pubmed publisher
Chang R, Eriksen J, Edwards R. The dual role of chloride in synaptic vesicle glutamate transport. elife. 2018;7: pubmed publisher
Giovannone A, Reales E, Bhattaram P, Fraile Ramos A, Weimbs T. Monoubiquitination of syntaxin 3 leads to retrieval from the basolateral plasma membrane and facilitates cargo recruitment to exosomes. Mol Biol Cell. 2017;28:2843-2853 pubmed publisher
Ruhe F, Olling A, Abromeit R, Rataj D, Grieschat M, Zeug A, et al. Overexpression of the Endosomal Anion/Proton Exchanger ClC-5 Increases Cell Susceptibility toward Clostridium difficile Toxins TcdA and TcdB. Front Cell Infect Microbiol. 2017;7:67 pubmed publisher
Cruse G, Beaven M, Music S, Bradding P, Gilfillan A, Metcalfe D. The CD20 homologue MS4A4 directs trafficking of KIT toward clathrin-independent endocytosis pathways and thus regulates receptor signaling and recycling. Mol Biol Cell. 2015;26:1711-27 pubmed publisher
Bohdanowicz M, Balkin D, De Camilli P, Grinstein S. Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling. Mol Biol Cell. 2012;23:176-87 pubmed publisher
product information
Catalog Number :
35138
Product Name :
mCherry-Rab5CA(Q79L)
article :
doi10.1091/mbc.E11-06-0489
id5093
pubmed_id22072788
bacterial resistance :
Kanamycin
cloning :
backbonepmCherry-C1
backbone_mutation
backbone_originClontech
backbone_size4722
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5XhoI
promoterCMV
sequencing_primer_3
sequencing_primer_5mCherry-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesRAB5
geneRAB5A
id5868
genbank_ids
mutationConstitutively Active- Q79L
nameRab5a
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagmCherry
resistance markers :
177
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA