| Reference |
|---|
Wu G, Wang Q, Wang D, Xiong F, Liu W, Chen J, et al. Targeting polycomb repressor complex 2-mediated bivalent promoter epigenetic silencing of secreted frizzled-related protein 1 inhibits cholangiocarcinoma progression. Clin Transl Med. 2023;13:e1502 pubmed publisher |
Lee D, Ahn H, Sim H, Choi E, Choi S, Jo Y, et al. A CRISPR activation screen identifies MUC-21 as critical for resistance to NK and T cell-mediated cytotoxicity. J Exp Clin Cancer Res. 2023;42:272 pubmed publisher |
Calvi xf1 o C, Ceballos C, Alfonso A, Jauregui P, Calleja Cervantes M, San Martín Uriz P, et al. Optimization of universal allogeneic CAR-T cells combining CRISPR and transposon-based technologies for treatment of acute myeloid leukemia. Front Immunol. 2023;14:1270843 pubmed publisher |
Molvi Z, Klatt M, Dao T, Urraca J, Scheinberg D, O Reilly R. The landscape of MHC-presented phosphopeptides yields actionable shared tumor antigens for cancer immunotherapy across multiple HLA alleles. J Immunother Cancer. 2023;11: pubmed publisher |
Baumer Y, Singh K, Baez A, Gutierrez Huerta C, Chen L, Igboko M, et al. Social Determinants modulate NK cell activity via obesity, LDL, and DUSP1 signaling. bioRxiv. 2023;: pubmed publisher |
Qi J, Zhu H, Li Y, Guan X, He Y, Ren G, et al. Creation of a High-Throughput Microfluidic Platform for Single-Cell Transcriptome Sequencing of Cell-Cell Interactions. Small Methods. 2023;7:e2300730 pubmed publisher |
Chebotarev A, Ledyaeva V, Patsap O, Ivanov A, Fedotov A, Belousov V, et al. Multimodal label-free imaging of murine hepatocellular carcinoma with a subcellular resolution. J Biophotonics. 2023;16:e202300228 pubmed publisher |
Afifi M, Crncec A, Cornwell J, Cataisson C, Paul D, Ghorab L, et al. Irreversible cell cycle exit associated with senescence is mediated by constitutive MYC degradation. Cell Rep. 2023;42:113079 pubmed publisher |
Yang C, You J, Pan Q, Tang Y, Cai L, Huang Y, et al. Targeted delivery of a PD-1-blocking scFv by CD133-specific CAR-T cells using nonviral Sleeping Beauty transposition shows enhanced antitumour efficacy for advanced hepatocellular carcinoma. BMC Med. 2023;21:327 pubmed publisher |
Krasnov G, Puzanov G, Dashinimaev E, Vishnyakova K, Kondratieva T, Chegodaev Y, et al. Tumor Suppressor Properties of Small C-Terminal Domain Phosphatases in Clear Cell Renal Cell Carcinoma. Int J Mol Sci. 2023;24: pubmed publisher |
Dobson L, Saunderson S, Smith Bell S, McLellan A. Sleeping Beauty kit sets provide rapid and accessible generation of artificial antigen-presenting cells for natural killer cell expansion. Immunol Cell Biol. 2023;101:847-856 pubmed publisher |
Merk Ahmad K, Bein J, Scharf S, Sch xe4 fer H, Bexte T, Ullrich E, et al. The RHOA Mutation G17V Does Not Lead to Increased Migration of Human Malignant T Cells but Is Associated with Matrix Remodelling. Cancers (Basel). 2023;15: pubmed publisher |
Gross S, Mohammadi F, Sanchez Aguila C, Zhan P, Liby T, Dane M, et al. Analysis and modeling of cancer drug responses using cell cycle phase-specific rate effects. Nat Commun. 2023;14:3450 pubmed publisher |
Muhammad A, Calandranis M, Li B, Yang T, Blackwell D, Harvey M, et al. High-throughput functional mapping of variants in an arrhythmia gene, KCNE1 , reveals novel biology. bioRxiv. 2023;: pubmed publisher |
Sugiyama M, Brown A, Vega Lugo J, Borges J, Scott A, Jaqaman K, et al. Confinement of unliganded EGFR by tetraspanin nanodomains gates EGFR ligand binding and signaling. Nat Commun. 2023;14:2681 pubmed publisher |
Stout A, Zhang X, Letcher S, Rittenberg M, Shub M, Chai K, et al. Engineered autocrine signaling eliminates muscle cell FGF2 requirements for cultured meat production. bioRxiv. 2023;: pubmed publisher |
Liu S, Hur Y, Cai X, Cong Q, Yang Y, Xu C, et al. A tissue injury sensing and repair pathway distinct from host pathogen defense. Cell. 2023;186:2127-2143.e22 pubmed publisher |
Thankarajan E, Oz S, Saady A, Kulbitski K, Kompanets M, Eisen M, et al. SNAP-Tag-Targeted MRI-Fluorescent Multimodal Probes. Chembiochem. 2023;:e202300172 pubmed publisher |
Sarparanta J, Jonson P, Reimann J, Vihola A, Luque H, Penttil xe4 S, et al. Extension of the DNAJB2a isoform in a dominant neuromyopathy family. Hum Mol Genet. 2023;: pubmed publisher |
Lee J, Brien H, Walton B, Eidman Z, Toda S, Lim W, et al. Instructional materials that control cellular activity through synthetic Notch receptors. Biomaterials. 2023;297:122099 pubmed publisher |
Zhao Y, Teng H, Deng Y, Sheldon M, Martínez C, Zhang J, et al. Long noncoding RNA Malat1 inhibits Tead3-Nfatc1-mediated osteoclastogenesis to suppress osteoporosis and bone metastasis. Res Sq. 2023;: pubmed publisher |
Wu Y, Zhou L, Zou Y, Zhang Y, Zhang M, Xu L, et al. Disrupting the phase separation of KAT8-IRF1 diminishes PD-L1 expression and promotes antitumor immunity. Nat Cancer. 2023;4:382-400 pubmed publisher |
Ribaux P, Wuillemin C, Petignat P, Delie F, Cohen M. NANO-SBT-PEDF delivery system: A promising approach against ovarian cancer?. Heliyon. 2023;9:e13676 pubmed publisher |
Stahn L, Rasi x144 ska J, Dehne T, Schreyer S, Hakus A, Gossen M, et al. Sleeping Beauty transposon system for GDNF overexpression of entrapped stem cells in fibrin hydrogel in a rat model of Parkinson's disease. Drug Deliv Transl Res. 2023;13:1745-1765 pubmed publisher |
Khabarova A, Koksharova G, Salnikov P, Belokopytova P, Mungalov R, Pristyazhnuk I, et al. A Cre-LoxP-based approach for combinatorial chromosome rearrangements in human HAP1 cells. Chromosome Res. 2023;31:11 pubmed publisher |
Dietrich N, Trotter K, Ward J, Archer T. BRG1 HSA domain interactions with BCL7 proteins are critical for remodeling and gene expression. Life Sci Alliance. 2023;6: pubmed publisher |
King C, Liu Y, Amato K, Schaack G, Hu T, Smith J, et al. Pathogen-driven CRISPR screens identify TREX1 as a regulator of DNA self-sensing during influenza virus infection. bioRxiv. 2023;: pubmed publisher |
Molvi Z, Klatt M, Dao T, Urraca J, Scheinberg D, O Reilly R. The landscape of MHC-presented phosphopeptides yields actionable shared tumor antigens for cancer immunotherapy across multiple HLA alleles. bioRxiv. 2023;: pubmed publisher |
Saratov G, Vladimirov V, Novoselov A, Ziganshin R, Chen G, Baymukhametov T, et al. Myelin Basic Protein Fragmentation by Engineered Human Proteasomes with Different Catalytic Phenotypes Revealed Direct Peptide Ligands of MS-Associated and Protective HLA Class I Molecules. Int J Mol Sci. 2023;24: pubmed publisher |
Sowinska W, Wawro M, Biswas D, Kochan J, Pustelny K, Solecka A, et al. The homeostatic function of Regnase-2 restricts neuroinflammation. FASEB J. 2023;37:e22798 pubmed publisher |
Kido T, Lau Y. Androgen receptor variant 7 exacerbates hepatocarcinogenesis in a c-MYC-driven mouse HCC model. Oncogenesis. 2023;12:4 pubmed publisher |
Bednash J, Johns F, Farkas D, Elhance A, Adair J, Cress K, et al. Inhibiting the Deubiquitinase UCHL1 Reduces SARS-CoV-2 Viral Uptake by ACE2. Am J Respir Cell Mol Biol. 2023;68:566-576 pubmed publisher |
Ng L, Ma H, Poon R. Cyclin A-CDK1 suppresses the expression of the CDK1 activator CDC25A to safeguard timely mitotic entry. J Biol Chem. 2023;299:102957 pubmed publisher |
Czarnek M, Kochan J, Wawro M, Myrczek R, Bereta J. Construction of a Set of Novel Transposon Vectors for Efficient Silencing of Protein and lncRNA Genes via CRISPR Interference. Mol Biotechnol. 2023;: pubmed publisher |
Lo L, Uchenunu O, Botelho R, Antonescu C, Karshafian R. AMPK is required for recovery from metabolic stress induced by ultrasound microbubble treatment. iScience. 2023;26:105883 pubmed publisher |
Luqman Fatah A, Watanabe Y, Uno K, Ishikawa F, Moran J, Miyoshi T. The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction. Nat Commun. 2023;14:203 pubmed publisher |
Calle B, Gonzalez Rodriguez E, Mahoney K, Cioce A, Bineva Todd G, Tastan O, et al. Bump-and-hole engineering of human polypeptide N-acetylgalactosamine transferases to dissect their protein substrates and glycosylation sites in cells. STAR Protoc. 2023;4:101974 pubmed publisher |
Arias Arias J, Molina Castro S, Monturiol Gross L, Lomonte B, Corrales Aguilar E. Stable production of recombinant SARS-CoV-2 receptor-binding domain in mammalian cells with co-expression of a fluorescent reporter and its validation as antigenic target for COVID-19 serology testing. Biotechnol Rep (Amst). 2023;37:e00780 pubmed publisher |
S xf6 llner J, Sake H, Frenzel A, Lechler R, Herrmann D, Fuchs W, et al. In vitro genome editing activity of Cas9 in somatic cells after random and transposon-based genomic Cas9 integration. PLoS ONE. 2022;17:e0279123 pubmed publisher |
Wen C, Tian Z, Li L, Chen T, Chen H, Dai J, et al. SRSF3 and HNRNPH1 Regulate Radiation-Induced Alternative Splicing of Protein Arginine Methyltransferase 5 in Hepatocellular Carcinoma. Int J Mol Sci. 2022;23: pubmed publisher |
Baleva M, Chicherin I, Piunova U, Zgoda V, Patrushev M, Levitskii S, et al. Pentatricopeptide Protein PTCD2 Regulates COIII Translation in Mitochondria of the HeLa Cell Line. Int J Mol Sci. 2022;23: pubmed publisher |
Yagi Y, Teramoto T, Kaieda S, Imai T, Sasaki T, Yagi M, et al. Construction of a Versatile, Programmable RNA-Binding Protein Using Designer PPR Proteins and Its Application for Splicing Control in Mammalian Cells. Cells. 2022;11: pubmed publisher |
Abakumova T, Vaneev A, Naumenko V, Shokhina A, Belousov V, Mikaelyan A, et al. Intravital electrochemical nanosensor as a tool for the measurement of reactive oxygen/nitrogen species in liver diseases. J Nanobiotechnology. 2022;20:497 pubmed publisher |
Hata K, Kobayashi N, Sugimura K, Qin W, Haxholli D, Chiba Y, et al. Structural basis for the unique multifaceted interaction of DPPA3 with the UHRF1 PHD finger. Nucleic Acids Res. 2022;50:12527-12542 pubmed publisher |
Kikuchi A, Onoda H, Yamaguchi K, Kori S, Matsuzawa S, Chiba Y, et al. Structural basis for activation of DNMT1. Nat Commun. 2022;13:7130 pubmed publisher |
Mohammadi F, Visagan S, Gross S, Karginov L, Lagarde J, Heiser L, et al. A lineage tree-based hidden Markov model quantifies cellular heterogeneity and plasticity. Commun Biol. 2022;5:1258 pubmed publisher |
Wang Y, Poon R. MARCH5 regulates mitotic apoptosis through MCL1-dependent and independent mechanisms. Cell Death Differ. 2022;: pubmed publisher |
Zhang P, Huang J, Zheng W, Chen L, Liu S, Liu A, et al. Single-base resolution mapping of 2'-O-methylation sites by an exoribonuclease-enriched chemical method. Sci China Life Sci. 2022;: pubmed publisher |
Pszenny V, Tjhin E, Alves Ferreira E, Spada S, Bouamr F, Nair V, et al. Using the Sleeping Beauty (SB) Transposon to Generate Stable Cells Producing Enveloped Virus-Like Particles (eVLPs) Pseudotyped with SARS-CoV-2 Proteins for Vaccination. Curr Protoc. 2022;2:e575 pubmed publisher |
Cioce A, Calle B, Rizou T, Lowery S, Bridgeman V, Mahoney K, et al. Cell-specific bioorthogonal tagging of glycoproteins. Nat Commun. 2022;13:6237 pubmed publisher |
Ong C, Cheng Y, Siddle H, Lyons A, Woods G, Flies A. Class II transactivator induces expression of MHC-I and MHC-II in transmissible Tasmanian devil facial tumours. Open Biol. 2022;12:220208 pubmed publisher |
Fan C, Kim D, An H, Park Y. Identifying an oligodendrocyte enhancer that regulates Olig2 expression. Hum Mol Genet. 2022;: pubmed publisher |
Monta xf1 o Rend xf3 n F, Walpole G, Krause M, Hammond G, Grinstein S, Fairn G. PtdIns(3,4)P2, Lamellipodin, and VASP coordinate actin dynamics during phagocytosis in macrophages. J Cell Biol. 2022;221: pubmed publisher |
Lo C, Chiu T, Liu Y, Pan P, Liu K, Hsu C, et al. Targeting the Phosphatidylserine-Immune Checkpoint with a Small-Molecule Maytansinoid Conjugate. J Med Chem. 2022;65:12802-12824 pubmed publisher |
Shi Y, Kim H, Hamann C, Rhea E, Brunger J, Lippmann E. Nuclear receptor ligand screening in an iPSC-derived in vitro blood-brain barrier model identifies new contributors to leptin transport. Fluids Barriers CNS. 2022;19:77 pubmed publisher |
Gogl G, Zámbó B, Kostmann C, Cousido Siah A, Morlet B, Durbesson F, et al. Quantitative fragmentomics allow affinity mapping of interactomes. Nat Commun. 2022;13:5472 pubmed publisher |
Bloom M, Song P, Virostko J, Yankeelov T, Sorace A. Quantifying the Effects of Combination Trastuzumab and Radiation Therapy in Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer. Cancers (Basel). 2022;14: pubmed publisher |
Leung H, Foo G, VanDongen A. Arc Regulates Transcription of Genes for Plasticity, Excitability and Alzheimer's Disease. Biomedicines. 2022;10: pubmed publisher |
Kazemi S, L xf3 pez Mu xf1 oz A, Holl xfd J, Jin L, Yewdell J, Dolan B. Variations in Cell Surface ACE2 Levels Alter Direct Binding of SARS-CoV-2 Spike Protein and Viral Infectivity: Implications for Measuring Spike Protein Interactions with Animal ACE2 Orthologs. J Virol. 2022;96:e0025622 pubmed publisher |
Liu H, Heller Trulli D, Moore C. Targeting the mRNA endonuclease CPSF73 inhibits breast cancer cell migration, invasion, and self-renewal. iScience. 2022;25:104804 pubmed publisher |
Battulin N, Korablev A, Ryzhkova A, Smirnov A, Kabirova E, Khabarova A, et al. The human EF1a promoter does not provide expression of the transgene in mice. Transgenic Res. 2022;31:525-535 pubmed publisher |
He J, Wu J, Chen J, Zhang S, Guo Y, Zhang X, et al. Identification of Estradiol Benzoate as an Inhibitor of HBx Using Inducible Stably Transfected HepG2 Cells Expressing HiBiT Tagged HBx. Molecules. 2022;27: pubmed publisher |
L xf3 pez Mu xf1 oz A, Kosik I, Hollý J, Yewdell J. Cell surface SARS-CoV-2 nucleocapsid protein modulates innate and adaptive immunity. Sci Adv. 2022;8:eabp9770 pubmed publisher |
Ehrler J, Brunst S, Tjaden A, Kilu W, Heering J, Hernández Olmos V, et al. Compilation and evaluation of a fatty acid mimetics screening library. Biochem Pharmacol. 2022;204:115191 pubmed publisher |
Igarashi N, Miyata K, Loo T, Chiba M, Hanyu A, Nishio M, et al. Hepatocyte growth factor derived from senescent cells attenuates cell competition-induced apical elimination of oncogenic cells. Nat Commun. 2022;13:4157 pubmed publisher |
Cheng Y, Ko Y, Ku H, Huang C, Yao Y, Liao Y, et al. Novel Paired Cell Lines for the Study of Lipid Metabolism and Cancer Stemness of Hepatocellular Carcinoma. Front Cell Dev Biol. 2022;10:821224 pubmed publisher |
Dolskiy A, Grishchenko I, Bodnev S, Nazarenko A, Smirnova A, Matveeva A, et al. Increased LAMP1 Expression Enhances SARS-CoV-1 and SARS-CoV-2 Production in Vero-Derived Transgenic Cell Lines. Mol Biol. 2022;56:463-468 pubmed publisher |
Johnson B, Chafin L, Farkas D, Adair J, Elhance A, Farkas L, et al. MicroID2: A Novel Biotin Ligase Enables Rapid Proximity Dependent Proteomics. Mol Cell Proteomics. 2022;:100256 pubmed publisher |
Moghimianavval H, Patel C, Mohapatra S, Hwang S, Kayikcioglu T, Bashirzadeh Y, et al. Engineering Functional Membrane-Membrane Interfaces by InterSpy. Small. 2022;:e2202104 pubmed publisher |
Bao X, Li Q, Chen J, Chen D, Ye C, Dai X, et al. Molecular Subgroups of Intrahepatic Cholangiocarcinoma Discovered by Single-Cell RNA Sequencing-Assisted Multiomics Analysis. Cancer Immunol Res. 2022;10:811-828 pubmed publisher |
Meijering A, Sarlós K, Nielsen C, Witt H, Harju J, Kerklingh E, et al. Nonlinear mechanics of human mitotic chromosomes. Nature. 2022;605:545-550 pubmed publisher |
Tse L, Meganck R, Dong S, Adams L, White L, Mallory M, et al. Generation of Mature DENVs via Genetic Modification and Directed Evolution. MBio. 2022;13:e0038622 pubmed publisher |
Kwon D, Gim G, Eom K, Lee J, Jang G. Application of transposon systems in the transgenesis of bovine somatic and germ cells. BMC Vet Res. 2022;18:156 pubmed publisher |
Jugel W, Tietze S, Daeg J, Appelhans D, Broghammer F, Aigner A, et al. Targeted Transposition of Minicircle DNA Using Single-Chain Antibody Conjugated Cyclodextrin-Modified Poly (Propylene Imine) Nanocarriers. Cancers (Basel). 2022;14: pubmed publisher |
Ursic Bedoya J, Chavey C, Desandré G, Meunier L, Dupuy A, Gonzalez Dopeso Reyes I, et al. Fibroblast growth factor 19 stimulates water intake. Mol Metab. 2022;60:101483 pubmed publisher |
Howard G, Jost T, Yankeelov T, Brock A. Quantification of long-term doxorubicin response dynamics in breast cancer cell lines to direct treatment schedules. PLoS Comput Biol. 2022;18:e1009104 pubmed publisher |
Kanada M, Linenfelser L, Cox E, Gilad A. A Dual-Reporter Platform for Screening Tumor-Targeted Extracellular Vesicles. Pharmaceutics. 2022;14: pubmed publisher |
O Neill M, Muhammad A, Li B, Wada Y, Hall L, Solus J, et al. Dominant negative effects of SCN5A missense variants. Genet Med. 2022;24:1238-1248 pubmed publisher |
Rasińska J, Klein C, Stahn L, Maidhof F, Pfeffer A, Schreyer S, et al. Transposon-mediated glial cell line-derived neurotrophic factor overexpression in human adipose tissue-derived mesenchymal stromal cells: A potential approach for neuroregenerative medicine?. J Tissue Eng Regen Med. 2022;16:515-529 pubmed publisher |
Czarnek M, Stalinska K, Sarad K, Bereta J. shRNAs targeting mouse Adam10 diminish cell response to proinflammatory stimuli independently of Adam10 silencing. Biol Open. 2022;11: pubmed publisher |
Jia Y, Li L, Lin Y, Gopal P, Shen S, Zhou K, et al. In vivo CRISPR screening identifies BAZ2 chromatin remodelers as druggable regulators of mammalian liver regeneration. Cell Stem Cell. 2022;29:372-385.e8 pubmed publisher |
Ribeiro Dos Santos A, Hogan M, Luther R, Brosh R, Maurano M. Genomic context sensitivity of insulator function. Genome Res. 2022;32:425-436 pubmed publisher |
de Wet L, Williams A, Gillard M, Kregel S, Lamperis S, Gutgesell L, et al. SOX2 mediates metabolic reprogramming of prostate cancer cells. Oncogene. 2022;41:1190-1202 pubmed publisher |
Guegan J, Lapouge M, Voisin L, Saba El Leil M, Tanguay P, Lévesque K, et al. Signaling by the tyrosine kinase Yes promotes liver cancer development. Sci Signal. 2022;15:eabj4743 pubmed publisher |
Gutierrez C, Al Khafaji A, Brenner E, Johnson K, Gohil S, Lin Z, et al. Multifunctional barcoding with ClonMapper enables high-resolution study of clonal dynamics during tumor evolution and treatment. Nat Cancer. 2021;2:758-772 pubmed publisher |
López Muñoz A, Kosik I, Hollý J, Yewdell J. Cell Surface SARS-CoV-2 Nucleocapsid Protein Modulates Innate and Adaptive Immunity. bioRxiv. 2021;: pubmed publisher |
Yao F, Deng Y, Zhao Y, Mei Y, Zhang Y, Liu X, et al. A targetable LIFR-NF-κB-LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis. Nat Commun. 2021;12:7333 pubmed publisher |
Liu X, Luongo C, Matsuoka Y, Park H, Santos C, Yang L, et al. A single intranasal dose of a live-attenuated parainfluenza virus-vectored SARS-CoV-2 vaccine is protective in hamsters. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher |
Galiakberova A, Surin A, Bakaeva Z, Sharipov R, Zhang D, Dorovskoy D, et al. IPSC-Derived Human Neurons with GCaMP6s Expression Allow In Vitro Study of Neurophysiological Responses to Neurochemicals. Neurochem Res. 2021;: pubmed publisher |
Rouland L, Duplan E, Ramos Dos Santos L, Bernardin A, Katula K, Manfioletti G, et al. Therapeutic potential of parkin as a tumor suppressor via transcriptional control of cyclins in glioblastoma cell and animal models. Theranostics. 2021;11:10047-10063 pubmed publisher |
Salnikov P, Khabarova A, Koksharova G, Mungalov R, Belokopytova P, Pristyazhnuk I, et al. Here and there: the double-side transgene localization. Vavilovskii Zhurnal Genet Selektsii. 2021;25:607-612 pubmed publisher |
Kazemi S, López Muñoz A, Hollý J, Jin L, Yewdell J, Dolan B. Variations in cell-surface ACE2 levels alter direct binding of SARS-CoV-2 Spike protein and viral infectivity: Implications for measuring Spike protein interactions with animal ACE2 orthologs. bioRxiv. 2021;: pubmed publisher |
Czarnek M, Sarad K, Karaś A, Kochan J, Bereta J. Non-targeting control for MISSION shRNA library silences SNRPD3 leading to cell death or permanent growth arrest. Mol Ther Nucleic Acids. 2021;26:711-731 pubmed publisher |
Zhang Y, Huang Y, Jin X, Chen J, Peng L, Wang D, et al. Overexpression of lncRNAs with endogenous lengths and functions using a lncRNA delivery system based on transposon. J Nanobiotechnology. 2021;19:303 pubmed publisher |
Tseng S, Liu L, Peng S, Kim J, Ferrall L, Hung C, et al. Control of Spontaneous HPV16 E6/E7 Expressing Oral Cancer in HLA-A2 (AAD) Transgenic Mice with Therapeutic HPV DNA Vaccine. J Biomed Sci. 2021;28:63 pubmed publisher |
Alvarez Suarez P, Nowak N, Protasiuk Filipunas A, Yamazaki H, Proszynski T, Gawor M. Drebrin Regulates Acetylcholine Receptor Clustering and Organization of Microtubules at the Postsynaptic Machinery. Int J Mol Sci. 2021;22: pubmed publisher |
Halbgebauer D, Roos J, Funcke J, Neubauer H, Hamilton B, Simon E, et al. Latent TGFβ-binding proteins regulate UCP1 expression and function via TGFβ2. Mol Metab. 2021;53:101336 pubmed publisher |
Dilsizoglu Senol A, Samarani M, Syan S, Guardia C, Nonaka T, Liv N, et al. α-Synuclein fibrils subvert lysosome structure and function for the propagation of protein misfolding between cells through tunneling nanotubes. PLoS Biol. 2021;19:e3001287 pubmed publisher |
Kim D, An H, Fan C, Park Y. Identifying oligodendrocyte enhancers governing Plp1 expression. Hum Mol Genet. 2021;: pubmed publisher |
Yu G, Yu Y, Ye H. Constructing a Smartphone-Controlled Semiautomatic Theranostic System for Glucose Homeostasis in Diabetic Mice. Methods Mol Biol. 2021;2312:141-158 pubmed publisher |
Henkle T, Lam B, Kung Y, Lin J, Tseng S, Ferrall L, et al. Development of a novel mouse model of spontaneous high-risk HPVE6/E7-expressing carcinoma in the cervicovaginal tract. Cancer Res. 2021;: pubmed publisher |
McDonnell M, Karvonen S, Gaba A, Flath B, Chelico L, Emerman M. Highly-potent, synthetic APOBEC3s restrict HIV-1 through deamination-independent mechanisms. PLoS Pathog. 2021;17:e1009523 pubmed publisher |
Wu M, Xia X, Hu J, Fowlkes N, Li S. WSX1 act as a tumor suppressor in hepatocellular carcinoma by downregulating neoplastic PD-L1 expression. Nat Commun. 2021;12:3500 pubmed publisher |
Alonso J, Smith A, Baker B. Tumor rejection properties of gp100209-specific T cells correlate with T cell receptor binding affinity towards the wild type rather than anchor-modified antigen. Mol Immunol. 2021;135:365-372 pubmed publisher |
Sapio R, Burns C, Pestov D. Effects of Hydrogen Peroxide Stress on the Nucleolar Redox Environment and Pre-rRNA Maturation. Front Mol Biosci. 2021;8:678488 pubmed publisher |
Yeung T, Lau H, Ma H, Poon R. One-step multiplex toolkit for efficient generation of conditional gene silencing human cell lines. Mol Biol Cell. 2021;32:1320-1330 pubmed publisher |
Johari M, Sarparanta J, Vihola A, Jonson P, Savarese M, Jokela M, et al. Missense mutations in small muscle protein X-linked (SMPX) cause distal myopathy with protein inclusions. Acta Neuropathol. 2021;142:375-393 pubmed publisher |
Koch A, Jeiler B, Roedig J, van Wijk S, Dolgikh N, Fulda S. Smac mimetics and TRAIL cooperate to induce MLKL-dependent necroptosis in Burkitt's lymphoma cell lines. Neoplasia. 2021;23:539-550 pubmed publisher |
Wang X, Zhang H, Sapio R, Yang J, Wong J, Zhang X, et al. SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer. Nat Commun. 2021;12:2259 pubmed publisher |
Hamar J, Kültz D. An efficient vector-based CRISPR/Cas9 system in an Oreochromis mossambicus cell line using endogenous promoters. Sci Rep. 2021;11:7854 pubmed publisher |
Ong C, Patchett A, Darby J, Chen J, Liu G, Lyons A, et al. NLRC5 regulates expression of MHC-I and provides a target for anti-tumor immunity in transmissible cancers. J Cancer Res Clin Oncol. 2021;147:1973-1991 pubmed publisher |
Sagara I, Woodford J, Dicko A, Zeguime A, Doucoure M, Kwan J, et al. SARS-CoV-2 seroassay optimization and performance in a population with high background reactivity in Mali. medRxiv. 2021;: pubmed publisher |
Dong Y, Zhang S, Gao X, Yin D, Wang T, Li Z, et al. HIF1α epigenetically repressed macrophages via CRISPR/Cas9-EZH2 system for enhanced cancer immunotherapy. Bioact Mater. 2021;6:2870-2880 pubmed publisher |
Zhao Y, Iyer S, Tavanaei M, Nguyen N, Lin A, Nguyen T. Proarrhythmic Electrical Remodeling by Noncardiomyocytes at Interfaces With Cardiomyocytes Under Oxidative Stress. Front Physiol. 2020;11:622613 pubmed publisher |
Smith A, Alonso J, Ayres C, Singh N, Hellman L, Baker B. Structurally silent peptide anchor modifications allosterically modulate T cell recognition in a receptor-dependent manner. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher |
Maslova E, Orishchenko K, Posukh O. Functional Evaluation of a Rare Variant c.516G>C (p.Trp172Cys) in the GJB2 (Connexin 26) Gene Associated with Nonsyndromic Hearing Loss. Biomolecules. 2021;11: pubmed publisher |
Dahyaleh K, Sung H, Prioriello M, Rengasamy P, Lam N, Kim J, et al. Iron overload reduces adiponectin receptor expression via a ROS/FOXO1-dependent mechanism leading to adiponectin resistance in skeletal muscle cells. J Cell Physiol. 2021;236:5339-5351 pubmed publisher |
Song P, Mansur A, Dugger K, Davis T, Howard G, Yankeelov T, et al. CD4 T-cell immune stimulation of HER2 + breast cancer cells alters response to trastuzumab in vitro. Cancer Cell Int. 2020;20:544 pubmed publisher |
Shi B, Gao D, Zhong L, Zhi M, Weng X, Xu J, et al. IRF-1 expressed in the inner cell mass of the porcine early blastocyst enhances the pluripotency of induced pluripotent stem cells. Stem Cell Res Ther. 2020;11:505 pubmed publisher |
Mulholland C, Nishiyama A, Ryan J, Nakamura R, Yiğit M, Glück I, et al. Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals. Nat Commun. 2020;11:5972 pubmed publisher |
Mao M, Chang C, Pickar Oliver A, Cervia L, Wang L, Ji J, et al. Redirecting Vesicular Transport to Improve Nonviral Delivery of Molecular Cargo. Adv Biosyst. 2020;4:e2000059 pubmed publisher |
Backstrom J, Sheng J, Wang M, Bernardo Colón A, Rex T. Optimization of S. aureus dCas9 and CRISPRi Elements for a Single Adeno-Associated Virus that Targets an Endogenous Gene. Mol Ther Methods Clin Dev. 2020;19:139-148 pubmed publisher |
Flies A, Darby J, Lennard P, Murphy P, Ong C, Pinfold T, et al. A novel system to map protein interactions reveals evolutionarily conserved immune evasion pathways on transmissible cancers. Sci Adv. 2020;6: pubmed publisher |
Stout A, Mirliani A, Soule Albridge E, Cohen J, Kaplan D. Engineering carotenoid production in mammalian cells for nutritionally enhanced cell-cultured foods. Metab Eng. 2020;62:126-137 pubmed publisher |
Jepsen W, De Both M, Siniard A, Ramsey K, Piras I, Naymik M, et al. Adenosine triphosphate binding cassette subfamily C member 1 (ABCC1) overexpression reduces APP processing and increases alpha- versus beta-secretase activity, in vitro. Biol Open. 2021;10: pubmed publisher |
Gerbracht J, Boehm V, Britto Borges T, Kallabis S, Wiederstein J, Ciriello S, et al. CASC3 promotes transcriptome-wide activation of nonsense-mediated decay by the exon junction complex. Nucleic Acids Res. 2020;48:8626-8644 pubmed publisher |
Laptev I, Shvetsova E, Levitskii S, Serebryakova M, Rubtsova M, Zgoda V, et al. METTL15 interacts with the assembly intermediate of murine mitochondrial small ribosomal subunit to form m4C840 12S rRNA residue. Nucleic Acids Res. 2020;: pubmed publisher |
VanOpstall C, Perike S, Brechka H, Gillard M, Lamperis S, Zhu B, et al. MEIS-mediated suppression of human prostate cancer growth and metastasis through HOXB13-dependent regulation of proteoglycans. elife. 2020;9: pubmed publisher |
Stiff T, Echegaray Iturra F, Pink H, Herbert A, Reyes Aldasoro C, Hochegger H. Prophase-Specific Perinuclear Actin Coordinates Centrosome Separation and Positioning to Ensure Accurate Chromosome Segregation. Cell Rep. 2020;31:107681 pubmed publisher |
Mbongue J, Alhoshani A, Rawson J, Garcia P, Gonzalez N, Ferreri K, et al. Tracking of an Oral Salmonella-Based Vaccine for Type 1 Diabetes in Non-obese Diabetic Mice. Front Immunol. 2020;11:712 pubmed publisher |
Hegarat N, Crncec A, Suarez Peredo Rodriguez M, Echegaray Iturra F, Gu Y, Busby O, et al. Cyclin A triggers Mitosis either via the Greatwall kinase pathway or Cyclin B. EMBO J. 2020;39:e104419 pubmed publisher |
Schumann B, MALAKER S, Wisnovsky S, Debets M, Agbay A, Fernandez D, et al. Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells. Mol Cell. 2020;78:824-834.e15 pubmed publisher |
Jin H, Ko M, Choi D, Kim J, Lee D, Kang S, et al. CD226hiCD8+ T Cells Are a Prerequisite for Anti-TIGIT Immunotherapy. Cancer Immunol Res. 2020;8:912-925 pubmed publisher |
Ardeljan D, Steranka J, Liu C, Li Z, Taylor M, Payer L, et al. Cell fitness screens reveal a conflict between LINE-1 retrotransposition and DNA replication. Nat Struct Mol Biol. 2020;27:168-178 pubmed publisher |
Czarnek M, Bereta J. Proteolytic Processing of Neuregulin 2. Mol Neurobiol. 2019;: pubmed publisher |
Gross S, Dane M, Bucher E, Heiser L. Individual Cells Can Resolve Variations in Stimulus Intensity along the IGF-PI3K-AKT Signaling Axis. Cell Syst. 2019;9:580-588.e4 pubmed publisher |
Krasnov G, Puzanov G, Afanasyeva M, Dashinimaev E, Vishnyakova K, Beniaminov A, et al. Tumor suppressor properties of the small C-terminal domain phosphatases in non-small cell lung cancer. Biosci Rep. 2019;39: pubmed publisher |
Laptev I, Shvetsova E, Levitskii S, Serebryakova M, Rubtsova M, Bogdanov A, et al. Mouse Trmt2B protein is a dual specific mitochondrial metyltransferase responsible for m5U formation in both tRNA and rRNA. RNA Biol. 2020;17:441-450 pubmed publisher |
Ribaux P, Britan A, Thumann G, Delie F, Petignat P, Cohen M. Malignant ascites: a source of therapeutic protein against ovarian cancer?. Oncotarget. 2019;10:5894-5905 pubmed publisher |
Farmer J, Allard Chamard H, Sun N, Ahmad M, Bertocchi A, Mahajan V, et al. Induction of metabolic quiescence defines the transitional to follicular B cell switch. Sci Signal. 2019;12: pubmed publisher |
Wasano K, Takahashi S, Rosenberg S, Kojima T, Mutai H, Matsunaga T, et al. Systematic quantification of the anion transport function of pendrin (SLC26A4) and its disease-associated variants. Hum Mutat. 2020;41:316-331 pubmed publisher |
Tews D, Pula T, Funcke J, Jastroch M, Keuper M, Debatin K, et al. Elevated UCP1 levels are sufficient to improve glucose uptake in human white adipocytes. Redox Biol. 2019;26:101286 pubmed publisher |
Johnson K, Howard G, Mo W, Strasser M, Lima E, Huang S, et al. Cancer cell population growth kinetics at low densities deviate from the exponential growth model and suggest an Allee effect. PLoS Biol. 2019;17:e3000399 pubmed publisher |
Sowinska W, Wawro M, Solecka A, Kasza A. Potential limitations of the Sleeping Beauty transposon use in gene expression studies. Acta Biochim Pol. 2019;66:263-268 pubmed publisher |
Haldeman J, Conway A, Arlotto M, Slentz D, Muoio D, Becker T, et al. Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing. Nucleic Acids Res. 2019;47:e23 pubmed publisher |
Price A, Cost A, Ungewiß H, Waschke J, Dunn A, Grashoff C. Mechanical loading of desmosomes depends on the magnitude and orientation of external stress. Nat Commun. 2018;9:5284 pubmed publisher |
Hu K, Li Y, Wu W, Chen H, Chen Z, Zhang Y, et al. High-performance gene expression and knockout tools using sleeping beauty transposon system. Mob DNA. 2018;9:33 pubmed publisher |
Liu Y, Tseng T, Soong R, Peng C, Cheng Y, Huang S, et al. A novel spontaneous hepatocellular carcinoma mouse model for studying T-cell exhaustion in the tumor microenvironment. J Immunother Cancer. 2018;6:144 pubmed publisher |
Bojar D, Fuhrer T, Fussenegger M. Purity by design: Reducing impurities in bioproduction by stimulus-controlled global translational downregulation of non-product proteins. Metab Eng. 2019;52:110-123 pubmed publisher |
Wooster A, Anderson T, Lowe D. Expression and characterization of soluble epitope-defined major histocompatibility complex (MHC) from stable eukaryotic cell lines. J Immunol Methods. 2019;464:22-30 pubmed publisher |
Howard G, Johnson K, Rodriguez Ayala A, Yankeelov T, Brock A. A multi-state model of chemoresistance to characterize phenotypic dynamics in breast cancer. Sci Rep. 2018;8:12058 pubmed publisher |
Li Y, Hermanson D, Moriarity B, Kaufman D. Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity. Cell Stem Cell. 2018;23:181-192.e5 pubmed publisher |
Kuchimaru T, Kataoka N, Nakagawa K, Isozaki T, Miyabara H, Minegishi M, et al. A reliable murine model of bone metastasis by injecting cancer cells through caudal arteries. Nat Commun. 2018;9:2981 pubmed publisher |
Bian S, Repic M, Guo Z, Kavirayani A, Burkard T, Bagley J, et al. Genetically engineered cerebral organoids model brain tumor formation. Nat Methods. 2018;15:631-639 pubmed publisher |
Pongsuchart M, Kuchimaru T, Yonezawa S, Tran D, Kha N, Hoang N, et al. Novel lymphoid enhancer-binding factor 1-cytoglobin axis promotes extravasation of osteosarcoma cells into the lungs. Cancer Sci. 2018;109:2746-2756 pubmed publisher |
Corsini N, Peer A, Moeseneder P, Roiuk M, Burkard T, Theussl H, et al. Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation. Cell Stem Cell. 2018;22:543-558.e12 pubmed publisher |
Fritzsch C, Baumgartner S, Kuban M, Steinshorn D, Reid G, Legewie S. Estrogen-dependent control and cell-to-cell variability of transcriptional bursting. Mol Syst Biol. 2018;14:e7678 pubmed publisher |
Wu M, Li J, Yue L, Bai L, Li Y, Chen J, et al. Establishment of Cre-mediated HBV recombinant cccDNA (rcccDNA) cell line for cccDNA biology and antiviral screening assays. Antiviral Res. 2018;152:45-52 pubmed publisher |
Lin Y, Yang M, Tseng S, Jiang R, Yang A, Farmer E, et al. Integration of Oncogenes via Sleeping Beauty as a Mouse Model of HPV16+ Oral Tumors and Immunologic Control. Cancer Immunol Res. 2018;: pubmed publisher |
Lancaster M, Corsini N, Wolfinger S, Gustafson E, Phillips A, Burkard T, et al. Guided self-organization and cortical plate formation in human brain organoids. Nat Biotechnol. 2017;35:659-666 pubmed publisher |
Gao M, Liu D. CRISPR/Cas9-based Pten knock-out and Sleeping Beauty Transposon-mediated Nras knock-in induces hepatocellular carcinoma and hepatic lipid accumulation in mice. Cancer Biol Ther. 2017;18:505-512 pubmed publisher |
Renner M, Lancaster M, Bian S, Choi H, Ku T, Peer A, et al. Self-organized developmental patterning and differentiation in cerebral organoids. EMBO J. 2017;36:1316-1329 pubmed publisher |
Lv J, Pan Y, Ju H, Zhou J, Cheng D, Shi H, et al. A Novel Ideal Radionuclide Imaging System for Non-invasively Cell Monitoring built on Baculovirus Backbone by Introducing Sleeping Beauty Transposon. Sci Rep. 2017;7:43879 pubmed publisher |
Barbon E, Ferrarese M, Van Wittenberghe L, Sanatine P, Ronzitti G, Collaud F, et al. Transposon-mediated Generation of Cellular and Mouse Models of Splicing Mutations to Assess the Efficacy of snRNA-based Therapeutics. Mol Ther Nucleic Acids. 2016;5:e392 pubmed publisher |
Jäckel C, Nogueira M, Ehni N, Kraus C, Ranke J, Dohmann M, et al. A vector platform for the rapid and efficient engineering of stable complex transgenes. Sci Rep. 2016;6:34365 pubmed publisher |
Rocha C, Lundin K, Behlke M, Zain R, El Andaloussi S, Smith C. Four Novel Splice-Switch Reporter Cell Lines: Distinct Impact of Oligonucleotide Chemistry and Delivery Vector on Biological Activity. Nucleic Acid Ther. 2016;26:381-391 pubmed |
Monjezi R, Miskey C, Gogishvili T, Schleef M, Schmeer M, Einsele H, et al. Enhanced CAR T-cell engineering using non-viral Sleeping Beauty transposition from minicircle vectors. Leukemia. 2017;31:186-194 pubmed publisher |
Looyenga B, VanOpstall C, Lee Z, Bell J, Lodge E, Wrobel K, et al. Determination of GLUT1 Oligomerization Parameters using Bioluminescent Förster Resonance Energy Transfer. Sci Rep. 2016;6:29130 pubmed publisher |
Yum S, Lee S, Kim H, Choi W, Park J, Lee W, et al. Efficient generation of transgenic cattle using the DNA transposon and their analysis by next-generation sequencing. Sci Rep. 2016;6:27185 pubmed publisher |
Wittmann T, Schindlbeck U, Höppner S, Kinting S, Frixel S, Kröner C, et al. Tools to explore ABCA3 mutations causing interstitial lung disease. Pediatr Pulmonol. 2016;51:1284-1294 pubmed publisher |
Kaberniuk A, Shemetov A, Verkhusha V. A bacterial phytochrome-based optogenetic system controllable with near-infrared light. Nat Methods. 2016;13:591-7 pubmed publisher |
Wu Y, Zhang T, Fang L, Chen Z, Song L, Cao J, et al. Sleeping Beauty transposon-based system for rapid generation of HBV-replicating stable cell lines. J Virol Methods. 2016;234:96-100 pubmed publisher |
Wittmann T, Frixel S, Höppner S, Schindlbeck U, Schams A, Kappler M, et al. Increased Risk of Interstitial Lung Disease in Children with a Single R288K Variant of ABCA3. Mol Med. 2016;22:183-191 pubmed publisher |
Sebe A, Ivics Z. Reprogramming of Human Fibroblasts to Induced Pluripotent Stem Cells with Sleeping Beauty Transposon-Based Stable Gene Delivery. Methods Mol Biol. 2016;1400:419-27 pubmed publisher |
Wang J, Singh M, Sun C, Besser D, Prigione A, Ivics Z, et al. Isolation and cultivation of naive-like human pluripotent stem cells based on HERVH expression. Nat Protoc. 2016;11:327-46 pubmed publisher |
Mátés L, Chuah M, Belay E, Jerchow B, Manoj N, Acosta Sanchez A, et al. Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates. Nat Genet. 2009;41:753-61 pubmed publisher |
