Krogsaeter E, McKetney J, Marquez A, Cakir Z, Stevenson E, Jang G, et al. Lysosomal proteomics reveals mechanisms of neuronal apoE4associated lysosomal dysfunction. bioRxiv. 2023;: pubmed publisher

Pellegrino E, Aylan B, Bussi C, Fearns A, Bernard E, Athanasiadi N, et al. Peroxisomal ROS control cytosolic Mycobacterium tuberculosis replication in human macrophages. J Cell Biol. 2023;222: pubmed publisher

Smid A, Garforth S, Obaid M, Bollons H, James J. Pre-T cell receptor localization and trafficking are independent of its signaling. J Cell Biol. 2023;222: pubmed publisher

Peng W, Schr xf6 der L, Song P, Wong Y, Krainc D. Parkin regulates amino acid homeostasis at mitochondria-lysosome (M/L) contact sites in Parkinson's disease. Sci Adv. 2023;9:eadh3347 pubmed publisher

Soha S, Santhireswaran A, Huq S, Casimir Powell J, Jenkins N, Hodgson G, et al. Improved imaging and preservation of lysosome dynamics using silver nanoparticle-enhanced fluorescence. Mol Biol Cell. 2023;:mbcE22060200 pubmed publisher

Tingskov S, D Agostino M, Login F, Tamma G, Nejsum L, N xf8 rregaard R. Tamoxifen Affects Aquaporin-3 Expression and Subcellular Localization in Rat and Human Renal Collecting Ducts. Cells. 2023;12: pubmed publisher

Raj N, Greune L, Kahms M, Mildner K, Franzkoch R, Psathaki O, et al. Early Endosomes Act as Local Exocytosis Hubs to Repair Endothelial Membrane Damage. Adv Sci (Weinh). 2023;10:e2300244 pubmed publisher

M xf6 ller K, Brambach M, Villani A, Gallo E, Gilmour D, Peri F. A role for the centrosome in regulating the rate of neuronal efferocytosis by microglia in vivo. elife. 2022;11: pubmed publisher

Sen A, Kallabis S, Gaedke F, J xfc ngst C, Boix J, N xfc chel J, et al. Mitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA. Nat Commun. 2022;13:6704 pubmed publisher

Jeon H, Kim Y, Hwang S, Seo J, Mun J. Restoration of Cathepsin D Level via L-Serine Attenuates PPA-Induced Lysosomal Dysfunction in Neuronal Cells. Int J Mol Sci. 2022;23: pubmed publisher

Tan J, Finkel T. A phosphoinositide signalling pathway mediates rapid lysosomal repair. Nature. 2022;609:815-821 pubmed publisher

K xfc ey C, Sittewelle M, Larocque G, Hern xe1 ndez Gonz xe1 lez M, Royle S. Recruitment of clathrin to intracellular membranes is sufficient for vesicle formation. elife. 2022;11: pubmed publisher

Jing Y, Kobayashi M, Vu H, Kasahara A, Chen X, Pham L, et al. Therapeutic advantage of targeting lysosomal membrane integrity supported by lysophagy in malignant glioma. Cancer Sci. 2022;113:2716-2726 pubmed publisher

Hancock Cerutti W, Wu Z, Xu P, Yadavalli N, Leonzino M, Tharkeshwar A, et al. ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling. J Cell Biol. 2022;221: pubmed publisher

Tanaka Y, Hino H, Takeya K, Eto M. Abemaciclib and Vacuolin-1 induce vacuole-like autolysosome formation - A new tool to study autophagosome-lysosome fusion. Biochem Biophys Res Commun. 2022;614:191-197 pubmed publisher

Tanaka Y, Kusumoto S, Honma Y, Takeya K, Eto M. Overexpression of progranulin increases pathological protein accumulation by suppressing autophagic flux. Biochem Biophys Res Commun. 2022;611:78-84 pubmed publisher

Belton T, Leisten E, Cisneros J, Wong Y. Live cell microscopy of mitochondria-lysosome contact site formation and tethering dynamics. STAR Protoc. 2022;3:101262 pubmed publisher

Kouzu H, Tatekoshi Y, Chang H, Shapiro J, McGee W, DE JESUS A, et al. ZFP36L2 suppresses mTORc1 through a P53-dependent pathway to prevent peripartum cardiomyopathy in mice. J Clin Invest. 2022;132: pubmed publisher

Lin J, McCann A, Sereesongsaeng N, Burden J, Alsa d A, Burden R, et al. USP17 is required for peripheral trafficking of lysosomes. EMBO Rep. 2022;23:e51932 pubmed publisher

Linders P, Ioannidis M, ter Beest M, van den Bogaart G. Fluorescence Lifetime Imaging of pH along the Secretory Pathway. ACS Chem Biol. 2022;17:240-251 pubmed publisher

Frei M, Tarnawski M, Roberti M, Koch B, Hiblot J, Johnsson K. Engineered HaloTag variants for fluorescence lifetime multiplexing. Nat Methods. 2021;: pubmed publisher

Podinovskaia M, Prescianotto Baschong C, Buser D, Spang A. A novel live-cell imaging assay reveals regulation of endosome maturation. elife. 2021;10: pubmed publisher

Creighton B, Afriyie S, Ajit D, Casingal C, Voos K, Reger J, et al. Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A. elife. 2021;10: pubmed publisher

George G, Ninagawa S, Yagi H, Furukawa J, Hashii N, Ishii Watabe A, et al. Purified EDEM3 or EDEM1 alone produces determinant oligosaccharide structures from M8B in mammalian glycoprotein ERAD. elife. 2021;10: pubmed publisher

Gan L, Liu D, Liu J, Chen E, Chen C, Liu L, et al. CD38 deficiency alleviates Ang II-induced vascular remodeling by inhibiting small extracellular vesicle-mediated vascular smooth muscle cell senescence in mice. Signal Transduct Target Ther. 2021;6:223 pubmed publisher

Chin M, Patwardhan A, Ang K, Wang A, Alquezar C, Welch M, et al. Genetically Encoded, pH-Sensitive mTFP1 Biosensor for Probing Lysosomal pH. ACS Sens. 2021;6:2168-2180 pubmed publisher

Baek M, Choe Y, Bannwarth S, Kim J, Maitra S, Dorn G, et al. TDP-43 and PINK1 mediate CHCHD10S59L mutation-induced defects in Drosophila and in vitro. Nat Commun. 2021;12:1924 pubmed publisher

Kim S, Wong Y, Gao F, Krainc D. Dysregulation of mitochondria-lysosome contacts by GBA1 dysfunction in dopaminergic neuronal models of Parkinson's disease. Nat Commun. 2021;12:1807 pubmed publisher

Benedetti L. Optogenetic Tools for Manipulating Protein Subcellular Localization and Intracellular Signaling at Organelle Contact Sites. Curr Protoc. 2021;1:e71 pubmed publisher

Khundadze M, Ribaudo F, Hussain A, Stahlberg H, Brocke Ahmadinejad N, Franzka P, et al. Mouse models for hereditary spastic paraplegia uncover a role of PI4K2A in autophagic lysosome reformation. Autophagy. 2021;:1-17 pubmed publisher

Sotoma S, Zhong C, Kah J, Yamashita H, Plakhotnik T, Harada Y, et al. In situ measurements of intracellular thermal conductivity using heater-thermometer hybrid diamond nanosensors. Sci Adv. 2021;7: pubmed publisher

Cantarero L, Juárez Escoto E, Civera Tregón A, Rodríguez Sanz M, Roldán M, Benitez R, et al. Mitochondria-lysosome membrane contacts are defective in GDAP1-related Charcot-Marie-Tooth disease. Hum Mol Genet. 2021;29:3589-3605 pubmed publisher

Lu M, van Tartwijk F, Lin J, Nijenhuis W, Parutto P, Fantham M, et al. The structure and global distribution of the endoplasmic reticulum network are actively regulated by lysosomes. Sci Adv. 2020;6: pubmed publisher

Wang J, Dang M, Day E. Inhibition of Wnt signaling by Frizzled7 antibody-coated nanoshells sensitizes triple-negative breast cancer cells to the autophagy regulator chloroquine. Nano Res. 2020;13:1693-1703 pubmed publisher

Houston R, Sekine S, Calderon M, Seifuddin F, Wang G, Kawagishi H, et al. Acetylation-mediated remodeling of the nucleolus regulates cellular acetyl-CoA responses. PLoS Biol. 2020;18:e3000981 pubmed publisher

Vaillant Beuchot L, Mary A, Pardossi Piquard R, Bourgeois A, Lauritzen I, Eysert F, et al. Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer's disease models and human brains. Acta Neuropathol. 2021;141:39-65 pubmed publisher

Alvarez Arce A, Lee Rivera I, Lopez E, López Colomé A. Thrombin-activated PAR1 membrane expression is regulated by Rab11a-RCP complex dissociation. Cell Signal. 2020;75:109748 pubmed publisher

Almacellas E, Pelletier J, Day C, Ambrosio S, Tauler A, Mauvezin C. Lysosomal degradation ensures accurate chromosomal segregation to prevent chromosomal instability. Autophagy. 2020;:1-18 pubmed publisher

Qiu K, Du Y, Liu J, Guan J, Chao H, Diao J. Super-resolution observation of lysosomal dynamics with fluorescent gold nanoparticles. Theranostics. 2020;10:6072-6081 pubmed publisher

Fu R, Zhang L, Li Y, Li B, Ming Y, Li Z, et al. Saikosaponin D inhibits autophagosome‑lysosome fusion and induces autophagy‑independent apoptosis in MDA‑MB‑231 breast cancer cells. Mol Med Rep. 2020;22:1026-1034 pubmed publisher

Stark M, Silva T, Levin G, Machuqueiro M, Assaraf Y. The Lysosomotropic Activity of Hydrophobic Weak Base Drugs is Mediated via Their Intercalation into the Lysosomal Membrane. Cells. 2020;9: pubmed publisher

Nijenhuis W, van Grinsven M, Kapitein L. An optimized toolbox for the optogenetic control of intracellular transport. J Cell Biol. 2020;219: pubmed publisher

Schormann W, Hariharan S, Andrews D. A reference library for assigning protein subcellular localizations by image-based machine learning. J Cell Biol. 2020;219: pubmed publisher

Lee H, Sim K, Kim H, Ju J, Pae A, Park J, et al. Aβ modulates actin cytoskeleton via SHIP2-mediated phosphoinositide metabolism. Sci Rep. 2019;9:15557 pubmed publisher

Scheefhals N, Catsburg L, Westerveld M, Blanpied T, Hoogenraad C, MacGillavry H. Shank Proteins Couple the Endocytic Zone to the Postsynaptic Density to Control Trafficking and Signaling of Metabotropic Glutamate Receptor 5. Cell Rep. 2019;29:258-269.e8 pubmed publisher

Juanes M, Isnardon D, Badache A, Brasselet S, Mavrakis M, Goode B. The role of APC-mediated actin assembly in microtubule capture and focal adhesion turnover. J Cell Biol. 2019;218:3415-3435 pubmed publisher

Wong Y, Peng W, Krainc D. Lysosomal Regulation of Inter-mitochondrial Contact Fate and Motility in Charcot-Marie-Tooth Type 2. Dev Cell. 2019;: pubmed publisher

Li Y, Jiang X, Zhang Y, Gao Z, Liu Y, Hu J, et al. Nuclear accumulation of UBC9 contributes to SUMOylation of lamin A/C and nucleophagy in response to DNA damage. J Exp Clin Cancer Res. 2019;38:67 pubmed publisher

Goyal R, Kapadia C, Melamed J, Riley R, Day E. Layer-by-layer assembled gold nanoshells for the intracellular delivery of miR-34a. Cell Mol Bioeng. 2018;11:383-396 pubmed publisher

Li S, Ahmad I, Shi J, Wang B, Yu C, Zhang L, et al. Murine Leukemia Virus Glycosylated Gag Reduces Murine SERINC5 Protein Expression at Steady-State Levels via the Endosome/Lysosome Pathway to Counteract SERINC5 Antiretroviral Activity. J Virol. 2019;93: pubmed publisher

Zhang Q, Presswalla F, Feathers K, Cao X, Hughes B, Zacks D, et al. A platform for assessing outer segment fate in primary human fetal RPE cultures. Exp Eye Res. 2019;178:212-222 pubmed publisher

Melamed J, Ioele S, Hannum A, Ullman V, Day E. Polyethylenimine-Spherical Nucleic Acid Nanoparticles against Gli1 Reduce the Chemoresistance and Stemness of Glioblastoma Cells. Mol Pharm. 2018;15:5135-5145 pubmed publisher

Melamed J, Kreuzberger N, Goyal R, Day E. Spherical Nucleic Acid Architecture Can Improve the Efficacy of Polycation-Mediated siRNA Delivery. Mol Ther Nucleic Acids. 2018;12:207-219 pubmed publisher

Durso W, D Autilia F, Amodeo R, Marchetti L, Cardarelli F. Probing labeling-induced lysosome alterations in living cells by imaging-derived mean squared displacement analysis. Biochem Biophys Res Commun. 2018;503:2704-2709 pubmed publisher

Shi J, Xiong R, Zhou T, Su P, Zhang X, Qiu X, et al. HIV-1 Nef Antagonizes SERINC5 Restriction by Downregulation of SERINC5 via the Endosome/Lysosome System. J Virol. 2018;92: pubmed publisher

Fu R, Deng Q, Zhang H, Hu X, Li Y, Liu Y, et al. A novel autophagy inhibitor berbamine blocks SNARE-mediated autophagosome-lysosome fusion through upregulation of BNIP3. Cell Death Dis. 2018;9:243 pubmed publisher

Wong Y, Ysselstein D, Krainc D. Mitochondria-lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis. Nature. 2018;554:382-386 pubmed publisher

Kondratskyi A, Kondratska K, Vanden Abeele F, Gordienko D, Dubois C, Toillon R, et al. Ferroquine, the next generation antimalarial drug, has antitumor activity. Sci Rep. 2017;7:15896 pubmed publisher

Yang H, Jana K, Rindler M, Coetzee W. The trafficking protein, EHD2, positively regulates cardiac sarcolemmal KATP channel surface expression: role in cardioprotection. FASEB J. 2018;32:1613-1625 pubmed publisher

Gaidt M, Ebert T, Chauhan D, Ramshorn K, Pinci F, Zuber S, et al. The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3. Cell. 2017;171:1110-1124.e18 pubmed publisher

Wood L, Larocque G, Clarke N, Sarkar S, Royle S. New tools for "hot-wiring" clathrin-mediated endocytosis with temporal and spatial precision. J Cell Biol. 2017;216:4351-4365 pubmed publisher

Bissig C, Hurbain I, Raposo G, van Niel G. PIKfyve activity regulates reformation of terminal storage lysosomes from endolysosomes. Traffic. 2017;18:747-757 pubmed publisher

Aoyama M, Yoshioka Y, Arai Y, Hirai H, Ishimoto R, Nagano K, et al. Intracellular trafficking of particles inside endosomal vesicles is regulated by particle size. J Control Release. 2017;260:183-193 pubmed publisher

Fettelschoss V, Burda P, Sagné C, Coelho D, De Laet C, Lutz S, et al. Clinical or ATPase domain mutations in ABCD4 disrupt the interaction between the vitamin B12-trafficking proteins ABCD4 and LMBD1. J Biol Chem. 2017;292:11980-11991 pubmed publisher

Swaminathan G, Zhu W, Plowey E. BECN1/Beclin 1 sorts cell-surface APP/amyloid ? precursor protein for lysosomal degradation. Autophagy. 2016;12:2404-2419 pubmed

Peng Y, Horwitz N, Lakatta E, Lin L. Mouse RAGE Variant 4 Is a Dominant Membrane Receptor that Does Not Shed to Generate Soluble RAGE. PLoS ONE. 2016;11:e0153657 pubmed publisher

Cohen Dvashi H, Israeli H, Shani O, Katz A, Diskin R. Role of LAMP1 Binding and pH Sensing by the Spike Complex of Lassa Virus. J Virol. 2016;90:10329-10338 pubmed publisher

Bellono N, Escobar I, Oancea E. A melanosomal two-pore sodium channel regulates pigmentation. Sci Rep. 2016;6:26570 pubmed publisher

Percher A, Ramakrishnan S, Thinon E, Yuan X, Yount J, Hang H. Mass-tag labeling reveals site-specific and endogenous levels of protein S-fatty acylation. Proc Natl Acad Sci U S A. 2016;113:4302-7 pubmed publisher

Gan K, Silverman M. Imaging organelle transport in primary hippocampal neurons treated with amyloid-β oligomers. Methods Cell Biol. 2016;131:425-51 pubmed publisher

Baulies A, Ribas V, Núñez S, Torres S, Alarcón Vila C, Martínez L, et al. Lysosomal Cholesterol Accumulation Sensitizes To Acetaminophen Hepatotoxicity by Impairing Mitophagy. Sci Rep. 2015;5:18017 pubmed publisher

Brennan T, Lin L, Brandstadter J, Rendell V, Dredge K, Huang X, et al. Heparan sulfate mimetic PG545-mediated antilymphoma effects require TLR9-dependent NK cell activation. J Clin Invest. 2016;126:207-19 pubmed publisher

Das U, Wang L, Ganguly A, Saikia J, Wagner S, Koo E, et al. Visualizing APP and BACE-1 approximation in neurons yields insight into the amyloidogenic pathway. Nat Neurosci. 2016;19:55-64 pubmed publisher

Falcon Perez J, Nazarian R, Sabatti C, Dell Angelica E. Distribution and dynamics of Lamp1-containing endocytic organelles in fibroblasts deficient in BLOC-3. J Cell Sci. 2005;118:5243-55 pubmed