| Reference |
|---|
Ebrahimighaei R, Tarassova N, Bond S, McNeill M, Hathway T, Vohra H, et al. Extracellular matrix stiffness controls cardiac fibroblast proliferation via the nuclear factor-Y (NF-Y) transcription factor. Biochim Biophys Acta Mol Cell Res. 2024;1871:119640 pubmed publisher
|
Claude Taupin A, Isnard P, Bagattin A, Kuperwasser N, Roccio F, Ruscica B, et al. The AMPK-Sirtuin 1-YAP axis is regulated by fluid flow intensity and controls autophagy flux in kidney epithelial cells. Nat Commun. 2023;14:8056 pubmed publisher
|
El Yousfi Y, Mora Molina R, L xf3 pez Rivas A, Yerbes R. Role of the YAP/TAZ-TEAD Transcriptional Complex in the Metabolic Control of TRAIL Sensitivity by the Mevalonate Pathway in Cancer Cells. Cells. 2023;12: pubmed publisher
|
Boogerd C, Perini I, Kyriakopoulou E, Han S, La P, van der Swaan B, et al. Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation. Nat Commun. 2023;14:4716 pubmed publisher
|
Lin W, Feathers R, Cooper L, Lewis Tuffin L, Chen J, Sarkaria J, et al. A Syx-RhoA-Dia1 signaling axis regulates cell cycle progression, DNA damage, and therapy resistance in glioblastoma. JCI Insight. 2023;8: pubmed publisher
|
Jiang M, Ding H, Huang Y, Cheng C, Lau C, Xia Y, et al. Thioridazine protects against disturbed flow-induced atherosclerosis by inhibiting RhoA/YAP-mediated endothelial inflammation. Acta Pharmacol Sin. 2023;44:1977-1988 pubmed publisher
|
Chu J, Li Y, He M, Zhang H, Yang L, Yang M, et al. Zinc finger and SCAN domain containing 1, ZSCAN1, is a novel stemness-related tumor suppressor and transcriptional repressor in breast cancer targeting TAZ. Front Oncol. 2023;13:1041688 pubmed publisher
|
Kang S, Kim J, Park A, Koh M, Shin W, Park G, et al. TRIM40 is a pathogenic driver of inflammatory bowel disease subverting intestinal barrier integrity. Nat Commun. 2023;14:700 pubmed publisher
|
Zhang S, Guo M, Jiang X, Tang L, Wu T, Bi G, et al. PXR triggers YAP-TEAD binding and Sirt2-driven YAP deacetylation and polyubiquitination to promote liver enlargement and regeneration in mice. Pharmacol Res. 2023;188:106666 pubmed publisher
|
Ippolito F, Consalvi V, Noce V, Battistelli C, Cicchini C, Tripodi M, et al. Extracellular signal-Regulated Kinase 5 (ERK5) is required for the Yes-associated protein (YAP) co-transcriptional activity. Cell Death Dis. 2023;14:32 pubmed publisher
|
Seavey C, Hallett A, Li S, Che K, Pobbati A, Ma S, et al. Loss of CDKN2A cooperates with WWTR1(TAZ)-CAMTA1 gene fusion to promote tumor progression in epithelioid hemangioendothelioma. Clin Cancer Res. 2023;: pubmed publisher
|
Csukasi F, Bosakova M, Bárta T, Martin J, Arcedo J, Barad M, et al. Skeletal diseases caused by mutations in PTH1R show aberrant differentiation of skeletal progenitors due to dysregulation of DEPTOR. Front Cell Dev Biol. 2022;10:963389 pubmed publisher
|
Ding H, Jiang M, Lau C, Luo J, Chan A, Wang L, et al. Curaxin CBL0137 inhibits endothelial inflammation and atherogenesis via suppression of the Src-YAP signalling axis. Br J Pharmacol. 2022;: pubmed publisher
|
Saini H, Choudhary M, Sharma H, Chowdhury S, Mukherjee S, Chowdhury R. Chloroquine induces transitory attenuation of proliferation of human lung cancer cells through regulation of mutant P53 and YAP. Mol Biol Rep. 2022;: pubmed publisher
|
Caire R, Audoux E, Thomas M, Dalix E, Peyron A, Rodriguez K, et al. YAP promotes cell-autonomous immune responses to tackle intracellular Staphylococcus aureus in vitro. Nat Commun. 2022;13:6995 pubmed publisher
|
Kim J, Luck C, Wu W, Ponce R, Lin Y, Gupta N, et al. Capicua suppresses YAP1 to limit tumorigenesis and maintain drug sensitivity in human cancer. Cell Rep. 2022;41:111443 pubmed publisher
|
Tchicaya Bouanga J, Hung Y, Schwartz J, Yoon D, Chotard E, Marty C, et al. A calpain-6/YAP axis in sarcoma stem cells that drives the outgrowth of tumors and metastases. Cell Death Dis. 2022;13:819 pubmed publisher
|
x160 vec J, x160 x165 astn xe1 M, Jane x10d kov xe1 L, Hr x10d kul xe1 k D, Vojt x11b chov xe1 M, Onhajzer J, et al. TROP2 Represents a Negative Prognostic Factor in Colorectal Adenocarcinoma and Its Expression Is Associated with Features of Epithelial-Mesenchymal Transition and Invasiveness. Cancers (Basel). 2022;14: pubmed publisher
|
Ballout F, Lu H, Chen L, Sriramajayam K, Que J, Meng Z, et al. APE1 redox function is required for activation of Yes-associated protein 1 under reflux conditions in Barrett's-associated esophageal adenocarcinomas. J Exp Clin Cancer Res. 2022;41:264 pubmed publisher
|
Guo Y, Zhu Z, Huang Z, Cui L, Yu W, Hong W, et al. CK2-induced cooperation of HHEX with the YAP-TEAD4 complex promotes colorectal tumorigenesis. Nat Commun. 2022;13:4995 pubmed publisher
|
Li J, Dai Y, Ge H, Guo S, Zhang W, Wang Y, et al. The deubiquitinase USP7 promotes HNSCC progression via deubiquitinating and stabilizing TAZ. Cell Death Dis. 2022;13:677 pubmed publisher
|
Ebrahimighaei R, Sala Newby G, Hudson C, Kimura T, Hathway T, Hawkins J, et al. Combined role for YAP-TEAD and YAP-RUNX2 signalling in substrate-stiffness regulation of cardiac fibroblast proliferation. Biochim Biophys Acta Mol Cell Res. 2022;1869:119329 pubmed publisher
|
Thirusangu P, Ray U, Sarkar Bhattacharya S, Oien D, Jin L, Staub J, et al. PFKFB3 regulates cancer stemness through the hippo pathway in small cell lung carcinoma. Oncogene. 2022;41:4003-4017 pubmed publisher
|
Huang Y, Ahmad U, Rehman A, Uttagomol J, Wan H. YAP Inhibition by Verteporfin Causes Downregulation of Desmosomal Genes and Proteins Leading to the Disintegration of Intercellular Junctions. Life (Basel). 2022;12: pubmed publisher
|
Choi S, Lee H, Cho N, Kim I, Cheon S, Park C, et al. RBFOX2-regulated TEAD1 alternative splicing plays a pivotal role in Hippo-YAP signaling. Nucleic Acids Res. 2022;: pubmed publisher
|
Rigiracciolo D, Nohata N, Lappano R, Cirillo F, Talia M, Adame García S, et al. Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC). J Exp Clin Cancer Res. 2022;41:193 pubmed publisher
|
Berthold R, Isfort I, Erkut C, Heinst L, Grünewald I, Wardelmann E, et al. Fusion protein-driven IGF-IR/PI3K/AKT signals deregulate Hippo pathway promoting oncogenic cooperation of YAP1 and FUS-DDIT3 in myxoid liposarcoma. Oncogenesis. 2022;11:20 pubmed publisher
|
Yu H, Yang Z, Xu M, Huang J, Yue Z, Guo B. Yap is essential for uterine decidualization through Rrm2/GSH/ROS pathway in response to Bmp2. Int J Biol Sci. 2022;18:2261-2276 pubmed publisher
|
Kim S, Basili T, Dopeso H, DA Cruz Paula A, Bi R, Issa Bhaloo S, et al. Recurrent WWTR1 S89W mutations and Hippo pathway deregulation in clear cell carcinomas of the cervix. J Pathol. 2022;: pubmed publisher
|
Sriramareddy S, Faião Flores F, Emmons M, Saha B, Chellappan S, Wyatt C, et al. HDAC11 activity contributes to MEK inhibitor escape in uveal melanoma. Cancer Gene Ther. 2022;: pubmed publisher
|
Li L, Li R, Wang Y. Identification of Small-molecule YAP-TEAD inhibitors by High-throughput docking for the Treatment of colorectal cancer. Bioorg Chem. 2022;122:105707 pubmed publisher
|
García García M, Sánchez Perales S, Jarabo P, Calvo E, Huyton T, Fu L, et al. Mechanical control of nuclear import by Importin-7 is regulated by its dominant cargo YAP. Nat Commun. 2022;13:1174 pubmed publisher
|
Zheng L, Luo C, Yang N, Pei H, Ji M, Shu Y, et al. Ionizing radiation-induced long noncoding RNA CRYBG3 regulates YAP/TAZ through mechanotransduction. Cell Death Dis. 2022;13:209 pubmed publisher
|
Zhao T, Wang Z, Fang J, Cheng W, Zhang Y, Huang J, et al. HTLV-1 activates YAP via NF-κB/p65 to promote oncogenesis. Proc Natl Acad Sci U S A. 2022;119: pubmed publisher
|
Xiao Y, Liu Q, Peng N, Li Y, Qiu D, Yang T, et al. Lovastatin Inhibits RhoA to Suppress Canonical Wnt/β-Catenin Signaling and Alternative Wnt-YAP/TAZ Signaling in Colon Cancer. Cell Transplant. 2022;31:9636897221075749 pubmed publisher
|
Tian Q, Gao H, Zhou Y, Zhu L, Yang J, Wang B, et al. RICH1 inhibits breast cancer stem cell traits through activating kinases cascade of Hippo signaling by competing with Merlin for binding to Amot-p80. Cell Death Dis. 2022;13:71 pubmed publisher
|
Guegan J, Lapouge M, Voisin L, Saba El Leil M, Tanguay P, Lévesque K, et al. Signaling by the tyrosine kinase Yes promotes liver cancer development. Sci Signal. 2022;15:eabj4743 pubmed publisher
|
Kumar B, Adebayo A, Prasad M, Capitano M, Wang R, Bhat Nakshatri P, et al. Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity. Sci Adv. 2022;8:eabh3375 pubmed publisher
|
Ahmad U, Parkinson E, Wan H. Desmoglein-3 induces YAP phosphorylation and inactivation during collective migration of oral carcinoma cells. Mol Oncol. 2022;16:1625-1649 pubmed publisher
|
Qin Y, Pei Z, Feng Z, Lin P, Wang S, Li Y, et al. Oncogenic Activation of YAP Signaling Sensitizes Ferroptosis of Hepatocellular Carcinoma via ALOXE3-Mediated Lipid Peroxidation Accumulation. Front Cell Dev Biol. 2021;9:751593 pubmed publisher
|
Park S, Frake R, Karabiyik C, Son S, Siddiqi F, Bento C, et al. Vinexin contributes to autophagic decline in brain ageing across species. Cell Death Differ. 2021;: pubmed publisher
|
Morice S, Danieau G, Tesfaye R, Mullard M, Brion R, Dupuy M, et al. Involvement of the TGF-β Signaling Pathway in the Development of YAP-Driven Osteosarcoma Lung Metastasis. Front Oncol. 2021;11:765711 pubmed publisher
|
Patrick S, Gowda P, Lathoria K, Suri V, Sen E. YAP1-mediated regulation of mitochondrial dynamics in IDH1 mutant gliomas. J Cell Sci. 2021;134: pubmed publisher
|
Xu S, Liu Y, Hu R, Wang M, Stöhr O, Xiong Y, et al. TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states. elife. 2021;10: pubmed publisher
|
Sun B, Zhong F, Xu C, Li Y, Zhao Y, Cao M, et al. Programmed cell death 10 promotes metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma via PP2Ac-mediated YAP activation. Cell Death Dis. 2021;12:849 pubmed publisher
|
Zhang S, Liang S, Wu D, Guo H, Ma K, Liu L. LncRNA coordinates Hippo and mTORC1 pathway activation in cancer. Cell Death Dis. 2021;12:822 pubmed publisher
|
Yang M, Han Y, Han Q, Rong X, Liu X, Ln X. KCTD11 inhibits progression of lung cancer by binding to β-catenin to regulate the activity of the Wnt and Hippo pathways. J Cell Mol Med. 2021;25:9411-9426 pubmed publisher
|
Mygland L, Brinch S, Strand M, Olsen P, Aizenshtadt A, Lund K, et al. Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines. iScience. 2021;24:102807 pubmed publisher
|
Berlew E, Kuznetsov I, Yamada K, Bugaj L, Boerckel J, Chow B. Single-Component Optogenetic Tools for Inducible RhoA GTPase Signaling. Adv Biol (Weinh). 2021;5:e2100810 pubmed publisher
|
Jeon Y, Yoo J, Rhee H, Kim Y, Il Kim G, Chung T, et al. YAP inactivation in estrogen receptor alpha-positive hepatocellular carcinoma with less aggressive behavior. Exp Mol Med. 2021;53:1055-1067 pubmed publisher
|
Mickle M, Adhikary G, Shrestha S, Xu W, Eckert R. VGLL4 inhibits YAP1/TEAD signaling to suppress the epidermal squamous cell carcinoma cancer phenotype. Mol Carcinog. 2021;60:497-507 pubmed publisher
|
Huang Y, Jedlickova H, Cai Y, Rehman A, Gammon L, Ahmad U, et al. Oxidative Stress-Mediated YAP Dysregulation Contributes to the Pathogenesis of Pemphigus Vulgaris. Front Immunol. 2021;12:649502 pubmed publisher
|
Park M, Kim J, Kim K, Kang S, Kim W, Kim J, et al. Circulating Small Extracellular Vesicles Activate TYRO3 to Drive Cancer Metastasis and Chemoresistance. Cancer Res. 2021;81:3539-3553 pubmed publisher
|
Li C, Li J, Gong S, Huang M, Li R, Xiong G, et al. Targeting the ILK/YAP axis by LFG-500 blocks epithelial-mesenchymal transition and metastasis. Acta Pharmacol Sin. 2021;: pubmed publisher
|
Han Q, Rong X, Lin X, Zhang X, Fan C, Zhao H, et al. WBP2 negatively regulates the Hippo pathway by competitively binding to WWC3 with LATS1 to promote non-small cell lung cancer progression. Cell Death Dis. 2021;12:384 pubmed publisher
|
Bi Lin K, Seshachalam P, Tuoc T, Stoykova A, Ghosh S, Singh M. Critical role of the BAF chromatin remodeling complex during murine neural crest development. PLoS Genet. 2021;17:e1009446 pubmed publisher
|
Pavel M, Park S, Frake R, Son S, Manni M, Bento C, et al. α-Catenin levels determine direction of YAP/TAZ response to autophagy perturbation. Nat Commun. 2021;12:1703 pubmed publisher
|
Vrbsky J, Vinarsky V, Perestrelo A, De La Cruz J, Martino F, Pompeiano A, et al. Evidence for discrete modes of YAP1 signaling via mRNA splice isoforms in development and diseases. Genomics. 2021;113:1349-1365 pubmed publisher
|
Quinn N, García Gutiérrez L, Doherty C, von Kriegsheim A, Fallahi E, Sacks D, et al. IQGAP1 Is a Scaffold of the Core Proteins of the Hippo Pathway and Negatively Regulates the Pro-Apoptotic Signal Mediated by This Pathway. Cells. 2021;10: pubmed publisher
|
Uneda A, Kurozumi K, Fujimura A, Fujii K, Ishida J, Shimazu Y, et al. Differentiated glioblastoma cells accelerate tumor progression by shaping the tumor microenvironment via CCN1-mediated macrophage infiltration. Acta Neuropathol Commun. 2021;9:29 pubmed publisher
|
Dai Y, Kyoyama H, Yang Y, Wang Y, Liu S, Wang Y, et al. A novel isoform of Homeodomain-interacting protein kinase-2 promotes YAP/TEAD transcriptional activity in NSCLC cells. Oncotarget. 2021;12:173-184 pubmed publisher
|
Delgado E, Erickson H, Tao J, Monga S, Duncan A, Anakk S. Scaffolding Protein IQGAP1 is Dispensable But Its Overexpression Promotes Hepatocellular Carcinoma via YAP1 Signaling. Mol Cell Biol. 2021;: pubmed publisher
|
Morice S, Mullard M, Brion R, Dupuy M, Renault S, Tesfaye R, et al. The YAP/TEAD Axis as a New Therapeutic Target in Osteosarcoma: Effect of Verteporfin and CA3 on Primary Tumor Growth. Cancers (Basel). 2020;12: pubmed publisher
|
Kong H, Kwon E, Kwon O, Lee H, Choi J, Kim Y, et al. Crosstalk between YAP and TGFβ regulates SERPINE1 expression in mesenchymal lung cancer cells. Int J Oncol. 2020;: pubmed publisher
|
Kim J, Kang W, Kang S, Park S, Kim J, Yang S, et al. Proline-rich tyrosine kinase 2 mediates transforming growth factor-beta-induced hepatic stellate cell activation and liver fibrosis. Sci Rep. 2020;10:21018 pubmed publisher
|
Bruschi F, Tardelli M, Einwallner E, Claudel T, Trauner M. PNPLA3 I148M Up-Regulates Hedgehog and Yap Signaling in Human Hepatic Stellate Cells. Int J Mol Sci. 2020;21: pubmed publisher
|
Wei L, Li P, Luo Y, Zhang M, Yan T, Yang Y, et al. PWP1 Promotes the Malignant Phenotypes of Lung Cancer Cells by Interacting with DVL2 and Merlin. Onco Targets Ther. 2020;13:10025-10037 pubmed publisher
|
Li Y, Chen M, Hu J, Sheng R, Lin Q, He X, et al. Volumetric Compression Induces Intracellular Crowding to Control Intestinal Organoid Growth via Wnt/β-Catenin Signaling. Cell Stem Cell. 2021;28:63-78.e7 pubmed publisher
|
Lorenzo Martín L, Fernández Parejo N, Menacho Márquez M, Rodríguez Fdez S, Robles Valero J, Zumalave S, et al. VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma. Nat Commun. 2020;11:4788 pubmed publisher
|
Yang H, Hu J, Chen J, Chen Z, Jiao F, Cui J, et al. RNA-binding protein Musashi2 regulates Hippo signaling via SAV1 and MOB1 in pancreatic cancer. Med Oncol. 2020;37:84 pubmed publisher
|
Cao D, Zhu G, Lu Y, Yang A, Chen D, Huang H, et al. Luteolin suppresses epithelial-mesenchymal transition and migration of triple-negative breast cancer cells by inhibiting YAP/TAZ activity. Biomed Pharmacother. 2020;129:110462 pubmed publisher
|
Meinhardt G, Haider S, Kunihs V, Saleh L, Pollheimer J, Fiala C, et al. Pivotal role of the transcriptional co-activator YAP in trophoblast stemness of the developing human placenta. Proc Natl Acad Sci U S A. 2020;117:13562-13570 pubmed publisher
|
Wu X, Wang Y, Zhong W, Cheng H, Tian Z. The Long Non-Coding RNA MALAT1 Enhances Ovarian Cancer Cell Stemness by Inhibiting YAP Translocation from Nucleus to Cytoplasm. Med Sci Monit. 2020;26:e922012 pubmed publisher
|
Waaler J, Mygland L, Tveita A, Strand M, Solberg N, Olsen P, et al. Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models. Commun Biol. 2020;3:196 pubmed publisher
|
Rigiracciolo D, Nohata N, Lappano R, Cirillo F, Talia M, Scordamaglia D, et al. IGF-1/IGF-1R/FAK/YAP Transduction Signaling Prompts Growth Effects in Triple-Negative Breast Cancer (TNBC) Cells. Cells. 2020;9: pubmed publisher
|
Guo Q, Quan M, Dong J, Bai J, Wang J, Han R, et al. The WW domains dictate isoform-specific regulation of YAP1 stability and pancreatic cancer cell malignancy. Theranostics. 2020;10:4422-4436 pubmed publisher
|
Li Q, Sun Y, Jarugumilli G, Liu S, Dang K, Cotton J, et al. Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription. Cell Stem Cell. 2020;26:675-692.e8 pubmed publisher
|
Sun H, Men J, Liu H, Liu M, Zhang H. FOXM1 facilitates breast cancer cell stemness and migration in YAP1-dependent manner. Arch Biochem Biophys. 2020;685:108349 pubmed publisher
|
Yuan Y, Park J, Feng A, Awasthi P, Wang Z, Chen Q, et al. YAP1/TAZ-TEAD transcriptional networks maintain skin homeostasis by regulating cell proliferation and limiting KLF4 activity. Nat Commun. 2020;11:1472 pubmed publisher
|
Zhou T, Gao B, Fan Y, Liu Y, Feng S, Cong Q, et al. Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin. elife. 2020;9: pubmed publisher
|
McNeill M, Wray J, Sala Newby G, Hindmarch C, Smith S, Ebrahimighaei R, et al. Nuclear actin regulates cell proliferation and migration via inhibition of SRF and TEAD. Biochim Biophys Acta Mol Cell Res. 2020;1867:118691 pubmed publisher
|
Nguyen T, Ralbovska A, Kugler J. RhoBTB Proteins Regulate the Hippo Pathway by Antagonizing Ubiquitination of LKB1. G3 (Bethesda). 2020;10:1319-1325 pubmed publisher
|
Irie K, Nagai T, Mizuno K. Furry protein suppresses nuclear localization of yes-associated protein (YAP) by activating NDR kinase and binding to YAP. J Biol Chem. 2020;295:3017-3028 pubmed publisher
|
Tanaka H, Homma H, Fujita K, Kondo K, Yamada S, Jin X, et al. YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathology. Nat Commun. 2020;11:507 pubmed publisher
|
Quan M, Chen Z, Jiao F, Xiao X, Xia Q, Chen J, et al. Lysine demethylase 2 (KDM2B) regulates hippo pathway via MOB1 to promote pancreatic ductal adenocarcinoma (PDAC) progression. J Exp Clin Cancer Res. 2020;39:13 pubmed publisher
|
You E, Ko P, Jeong J, Keum S, Kim J, Seo Y, et al. Dynein-mediated nuclear translocation of yes-associated protein through microtubule acetylation controls fibroblast activation. Cell Mol Life Sci. 2020;: pubmed publisher
|
Rodríguez Núñez P, Romero Pérez L, Amaral A, Puerto Camacho P, Jordán C, Marcilla D, et al. Hippo pathway effectors YAP1/TAZ induce an EWS-FLI1-opposing gene signature and associate with disease progression in Ewing sarcoma. J Pathol. 2019;: pubmed publisher
|
Isfort I, Elges S, Cyra M, Berthold R, Renner M, Mechtersheimer G, et al. Prevalence of the Hippo Effectors YAP1/TAZ in Tumors of Soft Tissue and Bone. Sci Rep. 2019;9:19704 pubmed publisher
|
Yin X, Choudhury M, Kang J, Schaefbauer K, Jung M, Andrianifahanana M, et al. Hexokinase 2 couples glycolysis with the profibrotic actions of TGF-β. Sci Signal. 2019;12: pubmed publisher
|
Li H, Li Q, Dang K, Ma S, Cotton J, Yang S, et al. YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression. Cell Rep. 2019;29:3200-3211.e4 pubmed publisher
|
Jimenez Martinez M, Ostalé C, van der Burg L, Galán Martínez J, Hardwick J, López Pérez R, et al. DUSP10 Is a Regulator of YAP1 Activity Promoting Cell Proliferation and Colorectal Cancer Progression. Cancers (Basel). 2019;11: pubmed publisher
|
Sayedyahossein S, Hedman A, Sacks D. Insulin suppresses transcriptional activity of yes-associated protein in insulin target cells. Mol Biol Cell. 2020;31:131-141 pubmed publisher
|
Giraud J, Molina Castro S, Seeneevassen L, Sifré E, Izotte J, Tiffon C, et al. Verteporfin targeting YAP1/TAZ-TEAD transcriptional activity inhibits the tumorigenic properties of gastric cancer stem cells. Int J Cancer. 2020;146:2255-2267 pubmed publisher
|
Costa R, Peruzzo R, Bachmann M, Montà G, Vicario M, Santinon G, et al. Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction. Cell Rep. 2019;28:1949-1960.e6 pubmed publisher
|
Sethunath V, Hu H, De Angelis C, Veeraraghavan J, Qin L, WANG N, et al. Targeting the Mevalonate Pathway to Overcome Acquired Anti-HER2 Treatment Resistance in Breast Cancer. Mol Cancer Res. 2019;17:2318-2330 pubmed publisher
|
Aureille J, Buffière Ribot V, Harvey B, Boyault C, Pernet L, Andersen T, et al. Nuclear envelope deformation controls cell cycle progression in response to mechanical force. EMBO Rep. 2019;20:e48084 pubmed publisher
|
Wu J, Minikes A, Gao M, Bian H, Li Y, Stockwell B, et al. Intercellular interaction dictates cancer cell ferroptosis via NF2-YAP signalling. Nature. 2019;572:402-406 pubmed publisher
|
Li J, Yao M, Zhu X, Li Q, He J, Chen L, et al. YAP-Induced Endothelial-Mesenchymal Transition in Oral Submucous Fibrosis. J Dent Res. 2019;98:920-929 pubmed publisher
|
Hennigan R, Fletcher J, Guard S, Ratner N. Proximity biotinylation identifies a set of conformation-specific interactions between Merlin and cell junction proteins. Sci Signal. 2019;12: pubmed publisher
|
Isfort I, Cyra M, Elges S, Kailayangiri S, Altvater B, Rossig C, et al. SS18-SSX-Dependent YAP/TAZ Signaling in Synovial Sarcoma. Clin Cancer Res. 2019;25:3718-3731 pubmed publisher
|
Cui J, Zhou Z, Yang H, Jiao F, Li N, Gao Y, et al. MST1 Suppresses Pancreatic Cancer Progression via ROS-Induced Pyroptosis. Mol Cancer Res. 2019;17:1316-1325 pubmed publisher
|
Feng X, Arang N, Rigiracciolo D, Lee J, Yeerna H, Wang Z, et al. A Platform of Synthetic Lethal Gene Interaction Networks Reveals that the GNAQ Uveal Melanoma Oncogene Controls the Hippo Pathway through FAK. Cancer Cell. 2019;35:457-472.e5 pubmed publisher
|
Smith S, Sessions R, Shoemark D, Williams C, Ebrahimighaei R, McNeill M, et al. Anti-proliferative and anti-migratory effects of a novel YAP-TEAD interaction inhibitor identified using in silico molecular docking. J Med Chem. 2019;: pubmed publisher
|
Ferrari N, Ranftl R, Chicherova I, Slaven N, Moeendarbary E, Farrugia A, et al. Dickkopf-3 links HSF1 and YAP/TAZ signalling to control aggressive behaviours in cancer-associated fibroblasts. Nat Commun. 2019;10:130 pubmed publisher
|
Escot S, Willnow D, Naumann H, Di Francescantonio S, Spagnoli F. Robo signalling controls pancreatic progenitor identity by regulating Tead transcription factors. Nat Commun. 2018;9:5082 pubmed publisher
|
Li Y, Xu J, Zhu G, Huang Z, Lu Y, Li X, et al. Apigenin suppresses the stem cell-like properties of triple-negative breast cancer cells by inhibiting YAP/TAZ activity. Cell Death Discov. 2018;4:105 pubmed publisher
|
Moreno Vicente R, Pavón D, Martin Padura I, Català Montoro M, Díez Sánchez A, Quílez Álvarez A, et al. Caveolin-1 Modulates Mechanotransduction Responses to Substrate Stiffness through Actin-Dependent Control of YAP. Cell Rep. 2018;25:1622-1635.e6 pubmed publisher
|
Choi H, Kim N, Kim B, Seo M, Heo J. TNF-α-Induced YAP/TAZ Activity Mediates Leukocyte-Endothelial Adhesion by Regulating VCAM1 Expression in Endothelial Cells. Int J Mol Sci. 2018;19: pubmed publisher
|
Mohamed A, Shah N, Hettmer S, Vargesson N, Wackerhage H. Analysis of the relationship between the KRAS G12V oncogene and the Hippo effector YAP1 in embryonal rhabdomyosarcoma. Sci Rep. 2018;8:15674 pubmed publisher
|
Lopez Almeida L, Sebbagh M, Bertucci F, Finetti P, Wicinski J, Marchetto S, et al. The SCRIB Paralog LANO/LRRC1 Regulates Breast Cancer Stem Cell Fate through WNT/β-Catenin Signaling. Stem Cell Reports. 2018;11:1040-1050 pubmed publisher
|
Melhuish T, Kowalczyk I, Manukyan A, Zhang Y, Shah A, Abounader R, et al. Myt1 and Myt1l transcription factors limit proliferation in GBM cells by repressing YAP1 expression. Biochim Biophys Acta Gene Regul Mech. 2018;1861:983-995 pubmed publisher
|
Li J, Wang H, Wang L, Tan R, Zhu M, Zhong X, et al. Decursin inhibits the growth of HepG2 hepatocellular carcinoma cells via Hippo/YAP signaling pathway. Phytother Res. 2018;32:2456-2465 pubmed publisher
|
Gao F, Yu X, Meng R, Wang J, Jia L. STARD13 is positively correlated with good prognosis and enhances 5-FU sensitivity via suppressing cancer stemness in hepatocellular carcinoma cells. Onco Targets Ther. 2018;11:5371-5381 pubmed publisher
|
Gegenfurtner F, Zisis T, Al Danaf N, Schrimpf W, Kliesmete Z, Ziegenhain C, et al. Transcriptional effects of actin-binding compounds: the cytoplasm sets the tone. Cell Mol Life Sci. 2018;75:4539-4555 pubmed publisher
|
Gao J, Rong Y, Huang Y, Shi P, Wang X, Meng X, et al. Cirrhotic stiffness affects the migration of hepatocellular carcinoma cells and induces sorafenib resistance through YAP. J Cell Physiol. 2019;234:2639-2648 pubmed publisher
|
Pavel M, Renna M, Park S, Menzies F, Ricketts T, Füllgrabe J, et al. Contact inhibition controls cell survival and proliferation via YAP/TAZ-autophagy axis. Nat Commun. 2018;9:2961 pubmed publisher
|
Martin D, Degese M, Vitale Cross L, Iglesias Bartolomé R, Valera J, Wang Z, et al. Assembly and activation of the Hippo signalome by FAT1 tumor suppressor. Nat Commun. 2018;9:2372 pubmed publisher
|
Xiong S, Lorenzen K, Couzens A, Templeton C, Rajendran D, Mao D, et al. Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment. Structure. 2018;26:1101-1115.e6 pubmed publisher
|
Gao L, Cheng X, Cao H. LncRNA THOR attenuates cisplatin sensitivity of nasopharyngeal carcinoma cells via enhancing cells stemness. Biochimie. 2018;152:63-72 pubmed publisher
|
Sun J, Wang X, Tang B, Liu H, Zhang M, Wang Y, et al. A tightly controlled Src-YAP signaling axis determines therapeutic response to dasatinib in renal cell carcinoma. Theranostics. 2018;8:3256-3267 pubmed publisher
|
Qin J, Shi H, Xu Y, Zhao F, Wang Q. Tanshinone IIA inhibits cervix carcinoma stem cells migration and invasion via inhibiting YAP transcriptional activity. Biomed Pharmacother. 2018;105:758-765 pubmed publisher
|
Choe M, Yoon Y, Kim J, Hwang S, Han Y, Kim J. miR-550a-3-5p acts as a tumor suppressor and reverses BRAF inhibitor resistance through the direct targeting of YAP. Cell Death Dis. 2018;9:640 pubmed publisher
|
Gibault F, Coevoet M, Sturbaut M, Farce A, Renault N, Allemand F, et al. Toward the Discovery of a Novel Class of YAP?TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP?TEAD Protein?Protein Interface. Cancers (Basel). 2018;10: pubmed publisher
|
Xu W, Chen C, Xu R, Li Y, Hu R, Li Z, et al. Knockdown of HuR represses osteosarcoma cells migration, invasion and stemness through inhibition of YAP activation and increases susceptibility to chemotherapeutic agents. Biomed Pharmacother. 2018;102:587-593 pubmed publisher
|
Yuan X, Wei W, Bao Q, Chen H, Jin P, Jiang W. Metformin inhibits glioma cells stemness and epithelial-mesenchymal transition via regulating YAP activity. Biomed Pharmacother. 2018;102:263-270 pubmed publisher
|
Lee T, Tseng Y, Nguyen P, Li Y, Ho C, Wu C. Enhanced YAP expression leads to EGFR TKI resistance in lung adenocarcinomas. Sci Rep. 2018;8:271 pubmed publisher
|
Crook Z, Sevilla G, Friend D, Brusniak M, Bandaranayake A, Clarke M, et al. Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets. Nat Commun. 2017;8:2244 pubmed publisher
|
Lee T, Tseng Y, Chang W, Chen Y, Kao Y, Chou T, et al. YAP1 is essential for tumor growth and is a potential therapeutic target for EGFR-dependent lung adenocarcinomas. Oncotarget. 2017;8:89539-89551 pubmed publisher
|
Matsudaira T, Mukai K, Noguchi T, Hasegawa J, Hatta T, Iemura S, et al. Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells. Nat Commun. 2017;8:1246 pubmed publisher
|
Ishihara S, Inman D, Li W, Ponik S, Keely P. Mechano-Signal Transduction in Mesenchymal Stem Cells Induces Prosaposin Secretion to Drive the Proliferation of Breast Cancer Cells. Cancer Res. 2017;77:6179-6189 pubmed publisher
|
Nguyen H, Kugler J, Loya A, Cohen S. USP21 regulates Hippo pathway activity by mediating MARK protein turnover. Oncotarget. 2017;8:64095-64105 pubmed publisher
|
Jia J, Qiao Y, Pilo M, Cigliano A, Liu X, Shao Z, et al. Tankyrase inhibitors suppress hepatocellular carcinoma cell growth via modulating the Hippo cascade. PLoS ONE. 2017;12:e0184068 pubmed publisher
|
Lee W, Chen P, Wu W, Wu H, Lan C, Huang Y, et al. Panobinostat sensitizes KRAS-mutant non-small-cell lung cancer to gefitinib by targeting TAZ. Int J Cancer. 2017;141:1921-1931 pubmed publisher
|
Dieffenbach P, Haeger C, Coronata A, Choi K, Varelas X, Tschumperlin D, et al. Arterial stiffness induces remodeling phenotypes in pulmonary artery smooth muscle cells via YAP/TAZ-mediated repression of cyclooxygenase-2. Am J Physiol Lung Cell Mol Physiol. 2017;313:L628-L647 pubmed publisher
|
Feng J, Yang H, Zhang Y, Wei H, Zhu Z, Zhu B, et al. Tumor cell-derived lactate induces TAZ-dependent upregulation of PD-L1 through GPR81 in human lung cancer cells. Oncogene. 2017;36:5829-5839 pubmed publisher
|
Mo W, Kwon Y, Jang I, Choi E, Kwon S, Kim J. Role of TAZ in Lysophosphatidic Acid-Induced Migration and Proliferation of Human Adipose-Derived Mesenchymal Stem Cells. Biomol Ther (Seoul). 2017;25:354-361 pubmed publisher
|
Totaro A, Castellan M, Battilana G, Zanconato F, Azzolin L, Giulitti S, et al. YAP/TAZ link cell mechanics to Notch signalling to control epidermal stem cell fate. Nat Commun. 2017;8:15206 pubmed publisher
|
Nardone G, Oliver De La Cruz J, Vrbsky J, Martini C, Pribyl J, Skladal P, et al. YAP regulates cell mechanics by controlling focal adhesion assembly. Nat Commun. 2017;8:15321 pubmed publisher
|
Walko G, Woodhouse S, Pisco A, Rognoni E, Liakath Ali K, Lichtenberger B, et al. A genome-wide screen identifies YAP/WBP2 interplay conferring growth advantage on human epidermal stem cells. Nat Commun. 2017;8:14744 pubmed publisher
|
Rohban M, Singh S, Wu X, Berthet J, Bray M, Shrestha Y, et al. Systematic morphological profiling of human gene and allele function via Cell Painting. elife. 2017;6: pubmed publisher
|
Nguyen H, Kugler J, Cohen S. DUB3 Deubiquitylating Enzymes Regulate Hippo Pathway Activity by Regulating the Stability of ITCH, LATS and AMOT Proteins. PLoS ONE. 2017;12:e0169587 pubmed publisher
|
Gu J, Rouse C, Xu X, Wang J, Onaitis M, Pendergast A. Inactivation of ABL kinases suppresses non-small cell lung cancer metastasis. JCI Insight. 2016;1:e89647 pubmed publisher
|
Qu L, Wu Z, Li Y, Xu Z, Liu B, Liu F, et al. A feed-forward loop between lncARSR and YAP activity promotes expansion of renal tumour-initiating cells. Nat Commun. 2016;7:12692 pubmed publisher
|
Duan Q, Xiao Y, Zhu L, Liu Z, Mao X, Zhou Z, et al. BET bromodomain is a novel regulator of TAZ and its activity. Biochim Biophys Acta. 2016;1859:1527-1537 pubmed publisher
|
Wu R, Liao C, Fu G, Hayenga H, Yang K, Ma Z, et al. p66Shc Couples Mechanical Signals to RhoA through Focal Adhesion Kinase-Dependent Recruitment of p115-RhoGEF and GEF-H1. Mol Cell Biol. 2016;36:2824-2837 pubmed publisher
|
Corvaisier M, Bauzone M, Corfiotti F, Renaud F, El Amrani M, Monté D, et al. Regulation of cellular quiescence by YAP/TAZ and Cyclin E1 in colon cancer cells: Implication in chemoresistance and cancer relapse. Oncotarget. 2016;7:56699-56712 pubmed publisher
|
Sayedyahossein S, Li Z, Hedman A, Morgan C, Sacks D. IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity. J Biol Chem. 2016;291:19261-73 pubmed publisher
|
Jang J, Kim M, Lee Y, Lee J, Kim D, Song S, et al. RAC-LATS1/2 signaling regulates YAP activity by switching between the YAP-binding partners TEAD4 and RUNX3. Oncogene. 2017;36:999-1011 pubmed publisher
|
DomÃnguez Calderón A, Ãvila Flores A, Ponce A, López Bayghen E, Calderón Salinas J, Luis Reyes J, et al. ZO-2 silencing induces renal hypertrophy through a cell cycle mechanism and the activation of YAP and the mTOR pathway. Mol Biol Cell. 2016;27:1581-95 pubmed publisher
|
Hoa L, Kulaberoglu Y, Gundogdu R, Cook D, Mavis M, Gomez M, et al. The characterisation of LATS2 kinase regulation in Hippo-YAP signalling. Cell Signal. 2016;28:488-497 pubmed publisher
|
Hsiao C, Lampe M, Nillasithanukroh S, Han W, Lian X, Palecek S. Human pluripotent stem cell culture density modulates YAP signaling. Biotechnol J. 2016;11:662-75 pubmed publisher
|
Kimura T, Duggirala A, Smith M, White S, Sala Newby G, Newby A, et al. The Hippo pathway mediates inhibition of vascular smooth muscle cell proliferation by cAMP. J Mol Cell Cardiol. 2016;90:1-10 pubmed publisher
|
Ukita M, Yamaguchi T, Ohata N, Tamura M. Sclerostin Enhances Adipocyte Differentiation in 3T3-L1 Cells. J Cell Biochem. 2016;117:1419-28 pubmed publisher
|
Yang S, Zhang L, Purohit V, Shukla S, Chen X, Yu F, et al. Active YAP promotes pancreatic cancer cell motility, invasion and tumorigenesis in a mitotic phosphorylation-dependent manner through LPAR3. Oncotarget. 2015;6:36019-31 pubmed publisher
|
Zhang L, Chen X, Stauffer S, Yang S, Chen Y, Dong J. CDK1 phosphorylation of TAZ in mitosis inhibits its oncogenic activity. Oncotarget. 2015;6:31399-412 pubmed publisher
|
Oku Y, Nishiya N, Shito T, Yamamoto R, Yamamoto Y, Oyama C, et al. Small molecules inhibiting the nuclear localization of YAP/TAZ for chemotherapeutics and chemosensitizers against breast cancers. FEBS Open Bio. 2015;5:542-9 pubmed publisher
|
Manderfield L, Engleka K, Aghajanian H, Gupta M, Yang S, Li L, et al. Pax3 and hippo signaling coordinate melanocyte gene expression in neural crest. Cell Rep. 2014;9:1885-1895 pubmed publisher
|
Aguilar A, Becker L, Tedeschi T, Heller S, Iomini C, Nachury M. Α-tubulin K40 acetylation is required for contact inhibition of proliferation and cell-substrate adhesion. Mol Biol Cell. 2014;25:1854-66 pubmed publisher
|
Wennmann D, Schmitz J, Wehr M, Krahn M, Koschmal N, Gromnitza S, et al. Evolutionary and molecular facts link the WWC protein family to Hippo signaling. Mol Biol Evol. 2014;31:1710-23 pubmed publisher
|
Mana Capelli S, Paramasivam M, Dutta S, McCollum D. Angiomotins link F-actin architecture to Hippo pathway signaling. Mol Biol Cell. 2014;25:1676-85 pubmed publisher
|
Dupont S, Morsut L, Aragona M, Enzo E, Giulitti S, Cordenonsi M, et al. Role of YAP/TAZ in mechanotransduction. Nature. 2011;474:179-83 pubmed publisher
|