This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
CMV500 A-SREBP1
catalog :
33357
citations: 2
Reference
Marwarha G, Claycombe Larson K, Lund J, Ghribi O. Palmitate-Induced SREBP1 Expression and Activation Underlies the Increased BACE 1 Activity and Amyloid Beta Genesis. Mol Neurobiol. 2018;: pubmed publisher
Rishi V, Gal J, Krylov D, Fridriksson J, Boysen M, Mandrup S, et al. SREBP-1 dimerization specificity maps to both the helix-loop-helix and leucine zipper domains: use of a dominant negative. J Biol Chem. 2004;279:11863-74 pubmed
product information
Catalog Number :
33357
Product Name :
CMV500 A-SREBP1
article :
doi10.1074/jbc.M308000200
id4920
pubmed_id14702347
bacterial resistance :
Ampicillin
cloning :
backboneCMV500
backbone_mutation
backbone_origin
backbone_size5500
promoterCMV
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
This is the dominant negative SREBP1- which contains an N-terminal acidic extension fused to the HLH-ZIP region of SREBP1.
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3HindIII
cloning_site_5XhoI
promoterCMV
sequencing_primer_3BGH-Rev
sequencing_primer_5CMV-Fwd
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesSREBP-1, SREBP1
geneSrebf1
id100689018
genbank_ids
mutationDominant Negative (see notes)
nameSREBP1
shRNA_sequence
size300
species
Cricetulus griseus (hamster)
tags
locationN terminal on backbone
tagFLAG
resistance markers :
1114
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA