This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
HA-Sos1
catalog :
32920
citations: 6
Reference
Nag J, Malka H, Sedley S, Appasamy P, Rudina T, Levi T, et al. PH-Binding Motif in PAR4 Oncogene: From Molecular Mechanism to Drug Design. Mol Cancer Ther. 2022;21:1415-1429 pubmed publisher
Hülsemann M, Sanchez C, Verkhusha P, Des Marais V, Mao S, Donnelly S, et al. TC10 regulates breast cancer invasion and metastasis by controlling membrane type-1 matrix metalloproteinase at invadopodia. Commun Biol. 2021;4:1091 pubmed publisher
Lee H, Choi B, Kang H, Kim H, Min A, Cha M, et al. Profiling of protein-protein interactions via single-molecule techniques predicts the dependence of cancers on growth-factor receptors. Nat Biomed Eng. 2018;2:239-253 pubmed publisher
Wong G, Zhou J, Liu J, Wu Z, Xu X, Li T, et al. Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition. Nat Med. 2018;24:968-977 pubmed publisher
Howes J, Akan D, Burns M, Rossanese O, Waterson A, Fesik S. Small Molecule-Mediated Activation of RAS Elicits Biphasic Modulation of Phospho-ERK Levels that Are Regulated through Negative Feedback on SOS1. Mol Cancer Ther. 2018;17:1051-1060 pubmed publisher
Yang S, Van Aelst L, Bar Sagi D. Differential interactions of human Sos1 and Sos2 with Grb2. J Biol Chem. 1995;270:18212-5 pubmed
product information
Catalog Number :
32920
Product Name :
HA-Sos1
article :
doi10.1074/jbc.270.31.18212
id4825
pubmed_id7629138
bacterial resistance :
Ampicillin
cloning :
backbonepCGN
backbone_mutation
backbone_originM Tanaka
backbone_size7500
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3SmaI
cloning_site_5XbaI
promoterCMV
sequencing_primer_3
sequencing_primer_5CMV-Fwd
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesGF1, GGF1, GINGF, HGF, NS4, SOS-1
geneSOS1
id6654
genbank_ids
mutation
nameSOS1
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagHA
resistance markers :
1093
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA