This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Human V5-IRF3-pcDNA3
catalog :
32713
citations: 8
Reference
Stilp A, Scherer M, K xf6 nig P, F xfc rstberger A, Kestler H, Stamminger T. The chromatin remodeling protein ATRX positively regulates IRF3-dependent type I interferon production and interferon-induced gene expression. PLoS Pathog. 2022;18:e1010748 pubmed publisher
Matissek S, Karbalivand M, Han W, Boutilier A, Yzar Garcia E, Kehoe L, et al. A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling. Oncotarget. 2022;13:944-959 pubmed publisher
Arwert E, Milford E, Rullan A, Derzsi S, Hooper S, Kato T, et al. STING and IRF3 in stromal fibroblasts enable sensing of genomic stress in cancer cells to undermine oncolytic viral therapy. Nat Cell Biol. 2020;22:758-766 pubmed publisher
Zhou H, Møhlenberg M, Terczyńska Dyla E, Winther K, Hansen N, Vad Nielsen J, et al. The IFNL4 Gene Is a Noncanonical Interferon Gene with a Unique but Evolutionarily Conserved Regulation. J Virol. 2020;94: pubmed publisher
He Z, Zhu X, Wen W, Yuan J, Hu Y, Chen J, et al. Dengue Virus Subverts Host Innate Immunity by Targeting Adaptor Protein MAVS. J Virol. 2016;90:7219-7230 pubmed publisher
Ni M, Xu T, Wang Y, He Y, Zhou Q, Huang C, et al. Inhibition of IRF3 expression reduces TGF-β1-induced proliferation of hepatic stellate cells. J Physiol Biochem. 2016;72:9-23 pubmed publisher
Andersen L, Mørk N, Reinert L, Kofod Olsen E, Narita R, Jørgensen S, et al. Functional IRF3 deficiency in a patient with herpes simplex encephalitis. J Exp Med. 2015;212:1371-9 pubmed publisher
Zhu J, Smith K, Hsieh P, Mburu Y, Chattopadhyay S, Sen G, et al. High-throughput screening for TLR3-IFN regulatory factor 3 signaling pathway modulators identifies several antipsychotic drugs as TLR inhibitors. J Immunol. 2010;184:5768-76 pubmed publisher
product information
Catalog Number :
32713
Product Name :
Human V5-IRF3-pcDNA3
article :
doi10.4049/jimmunol.0903559
id4763
pubmed_id20382888
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5400
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3XbaI
cloning_site_5EcoRI
promoterCMV
sequencing_primer_3SP6
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesIIAE7
geneIRF3
id3661
genbank_ids
mutation
nameIRF3
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on insert
tagV5
resistance markers :
1076
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA