This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
hATMS1981A
catalog :
32300
citations: 6
Reference
Baughan S, Darwiche F, Tainsky M. Functional analysis of ATM variants in a high risk cohort provides insight into missing heritability. Cancer Genet. 2022;264-265:40-49 pubmed publisher
Zhang J, Wu Q, Zhu L, Xie S, Tu L, Yang Y, et al. SERPINE2/PN-1 regulates the DNA damage response and radioresistance by activating ATM in lung cancer. Cancer Lett. 2022;524:268-283 pubmed publisher
Zhao J, Nguyen L, Nguyen L, Dang X, Cao D, Khanal S, et al. ATM Deficiency Accelerates DNA Damage, Telomere Erosion, and Premature T Cell Aging in HIV-Infected Individuals on Antiretroviral Therapy. Front Immunol. 2019;10:2531 pubmed publisher
Qian M, Liu Z, Peng L, Tang X, Meng F, Ao Y, et al. Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria. elife. 2018;7: pubmed publisher
Zhao J, Dang X, Zhang P, Nguyen L, Cao D, Wang L, et al. Insufficiency of DNA repair enzyme ATM promotes naive CD4 T-cell loss in chronic hepatitis C virus infection. Cell Discov. 2018;4:16 pubmed publisher
Bakkenist C, Kastan M. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature. 2003;421:499-506 pubmed
product information
Catalog Number :
32300
Product Name :
hATMS1981A
article :
doi10.1038/nature01368
id4624
pubmed_id12556884
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3.1
backbone_mutation
backbone_origininvitrogen
backbone_size5428
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth temp :
see attachment
origin :
30
pi :
alt_names
ATI
ATA
ATDC
cloning
clone_methodRestriction Enzyme
cloning_site_3Xho I
cloning_site_5XhoI-SAl I
promoter
sequencing_primer_3BGHrev
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed1
entrez_gene
aliasesAT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1
geneATM
id472
genbank_ids
mutationS1981A
nameATM
shRNA_sequence
size9581
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagFlag
locationN terminal on backbone
tagHis
resistance markers :
915
tags :
Unknown
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA