This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pBabe EGFR(T790M)
catalog :
32070
citations: 7
Reference
Lee C, Kim M, Kim D, Kim T, Kim S, Im S, et al. Acquired Resistance Mechanism of EGFR Kinase Domain Duplication to EGFR TKIs in Non-Small Cell Lung Cancer. Cancer Res Treat. 2021;: pubmed publisher
Arjuna S, Venkataram R, Dechamma P, Chakraborty G, Babu N, D Cruz A, et al. Non-invasive detection of EGFR mutations by cell-free loop-mediated isothermal amplification (CF-LAMP). Sci Rep. 2020;10:17559 pubmed publisher
Arjuna S, Chakraborty G, Venkataram R, Dechamma P, Chakraborty A. Detection of epidermal growth factor receptor T790M mutation by allele-specific loop mediated isothermal amplification. J Carcinog. 2020;19:3 pubmed publisher
Weng Y, Fan X, Bai Y, Wang S, Huang H, Yang H, et al. SLC2A5 promotes lung adenocarcinoma cell growth and metastasis by enhancing fructose utilization. Cell Death Discov. 2018;4:38 pubmed publisher
Hidaka N, Iwama E, Kubo N, Harada T, Miyawaki K, Tanaka K, et al. Most T790M mutations are present on the same EGFR allele as activating mutations in patients with non-small cell lung cancer. Lung Cancer. 2017;108:75-82 pubmed publisher
Dong Y, Hou W, Li Y, Liu D, Hao G, Zhang H, et al. Unexpected requirement for a binding partner of the syntaxin family in phagocytosis by murine testicular Sertoli cells. Cell Death Differ. 2016;23:787-800 pubmed publisher
Yuza Y, Glatt K, Jiang J, Greulich H, Minami Y, Woo M, et al. Allele-dependent variation in the relative cellular potency of distinct EGFR inhibitors. Cancer Biol Ther. 2007;6:661-7 pubmed
product information
Catalog Number :
32070
Product Name :
pBabe EGFR(T790M)
article :
doi10.4161/cbt.6.5.4003
id4299
pubmed_id17495523
bacterial resistance :
Ampicillin
cloning :
backbonepBABEpuro
backbone_mutation
backbone_origin
backbone_size5169
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3SnaB1
cloning_site_5SnaB1
promoter
sequencing_primer_3
sequencing_primer_5pBABE 5'
site_3_destroyed1
site_5_destroyed1
entrez_gene
aliasesERBB, ERBB1, ERRP, HER1, NISBD2, PIG61, mENA
geneEGFR
id1956
genbank_ids
mutationT790M
nameEGFR
shRNA_sequence
size3600
species
9606
Homo sapiens
tags
resistance markers :
338
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA