This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pRK5-TGF beta Type II receptor Flag
catalog :
31719
citations: 3
Reference
Shih Wei W, Chih Ling C, Kao Y, Martin R, Knölker H, Shiao M, et al. Pentabromopseudilin: a myosin V inhibitor suppresses TGF-? activity by recruiting the type II TGF-? receptor to lysosomal degradation. J Enzyme Inhib Med Chem. 2018;33:920-935 pubmed publisher
Juarez P, Fournier P, Mohammad K, McKenna R, Davis H, Peng X, et al. Halofuginone inhibits TGF-?/BMP signaling and in combination with zoledronic acid enhances inhibition of breast cancer bone metastasis. Oncotarget. 2017;8:86447-86462 pubmed publisher
Rys J, DuFort C, Monteiro D, Baird M, Oses Prieto J, Chand S, et al. Discrete spatial organization of TGFβ receptors couples receptor multimerization and signaling to cellular tension. elife. 2015;4:e09300 pubmed publisher
product information
Catalog Number :
31719
Product Name :
pRK5-TGF beta Type II receptor Flag
article :
doi
id4485
pubmed_id
bacterial resistance :
Ampicillin
cloning :
backbonepRK5
backbone_mutation
backbone_origin
backbone_size4716
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Please note that this plasmid has a single nucleotide mismatch with TbRII mRNA. This mismatch has no effect on plasmid function.
origin :
37
pi :
alt_names
TGFBR2
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3SV40pA-R
sequencing_primer_5SP6
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAAT3, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, TAAD2, TBR-ii, TBRII, TGFR-2, TGFbeta-RII, tbetaR-II
geneTGFBR2
id7048
genbank_ids
mutation
nameTGF beta Type II Receptor
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationC terminal on insert
tagFLAG
resistance markers :
115
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA