This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pRK5F-TACE
catalog :
31713
citations: 7
Reference
Harte J, Wakerlin S, Lindsay A, McCarthy J, Coleman Vaughan C. Metalloprotease-Dependent S2'-Activation Promotes Cell-Cell Fusion and Syncytiation of SARS-CoV-2. Viruses. 2022;14: pubmed publisher
Scherm M, Gangloff M, Gay N. Activation of Toll-like receptor 4 by Ebola virus-shed glycoprotein is direct and requires the internal fusion loop but not glycosylation. Cell Rep. 2022;41:111562 pubmed publisher
Ma X, Takahashi Y, Wu W, Liang W, Chen J, Chakraborty D, et al. ADAM17 mediates ectodomain shedding of the soluble VLDL receptor fragment in the retinal epithelium. J Biol Chem. 2021;297:101185 pubmed publisher
Saha S, Choi H, Yang G, Biswas P, Kim K, Kang G, et al. GPR50 Promotes Hepatocellular Carcinoma Progression via the Notch Signaling Pathway through Direct Interaction with ADAM17. Mol Ther Oncolytics. 2020;17:332-349 pubmed publisher
Lu Y, Wan J, Yang Z, Lei X, Niu Q, Jiang L, et al. Regulated intramembrane proteolysis of the AXL receptor kinase generates an intracellular domain that localizes in the nucleus of cancer cells. FASEB J. 2017;31:1382-1397 pubmed publisher
Luo Y, Jacobs E, Greco T, Mohammed K, Tong T, Keegan S, et al. HIV-host interactome revealed directly from infected cells. Nat Microbiol. 2016;1:16068 pubmed
Liu C, Xu P, Lamouille S, Xu J, Derynck R. TACE-mediated ectodomain shedding of the type I TGF-beta receptor downregulates TGF-beta signaling. Mol Cell. 2009;35:26-36 pubmed publisher
product information
Catalog Number :
31713
Product Name :
pRK5F-TACE
article :
doi10.1016/j.molcel.2009.06.018
id4484
pubmed_id19595713
bacterial resistance :
Ampicillin
cloning :
backbonepRK5
backbone_mutation
backbone_origin
backbone_size4716
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Mammalian expression of human TACE (ADAM17)
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3SV40pA-R
sequencing_primer_5SP6
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesADAM18, CD156B, CSVP, NISBD, NISBD1, TACE
geneADAM17
id6868
genbank_ids
mutation
nameTACE
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationC terminal on insert
tagFLAG
resistance markers :
115
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA