This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Slug_pGL2
catalog :
31695
citations: 5
Reference
Zhang Z, Wang X, Kim M, He D, Wang C, Fong K, et al. Downregulation of EZH2 inhibits epithelial-mesenchymal transition in enzalutamide-resistant prostate cancer. Prostate. 2023;: pubmed publisher
Wei C, Khan M, Du J, Cheng J, Tania M, Leung E, et al. Cordycepin Inhibits Triple-Negative Breast Cancer Cell Migration and Invasion by Regulating EMT-TFs SLUG, TWIST1, SNAIL1, and ZEB1. Front Oncol. 2022;12:898583 pubmed publisher
Xie Y, Liu S, Lu W, Yang Q, Williams K, Binhazim A, et al. Slug regulates E-cadherin repression via p19Arf in prostate tumorigenesis. Mol Oncol. 2014;8:1355-64 pubmed publisher
Carpenter R, Paw I, Dewhirst M, Lo H. Akt phosphorylates and activates HSF-1 independent of heat shock, leading to Slug overexpression and epithelial-mesenchymal transition (EMT) of HER2-overexpressing breast cancer cells. Oncogene. 2015;34:546-57 pubmed publisher
Fujita N, Jaye D, Kajita M, Geigerman C, Moreno C, Wade P. MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer. Cell. 2003;113:207-19 pubmed
product information
Catalog Number :
31695
Product Name :
Slug_pGL2
article :
doi10.1016/S0092-8674(03)00234-4
id4481
pubmed_id12705869
bacterial resistance :
Ampicillin
cloning :
backbonepGL2_Basic
backbone_mutation
backbone_origin
backbone_size5598
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Luciferase
growth notes :
Contains Slug promoter (-908 to -2) sequence upstream of luciferase
origin :
37
pi :
alt_names
SNAI2
cloning
clone_methodRestriction Enzyme
cloning_site_3HindIII
cloning_site_5KpnI
promoter
sequencing_primer_3
sequencing_primer_5n/a
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesSLUG, SLUGH, SLUGH1, SNAIL2, WS2D
geneSNAI2
id6591
genbank_ids
NM_003068
mutation
nameSlug
shRNA_sequence
size906
species
9606
Homo sapiens
tags
resistance markers :
1012
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA