This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Snail_pGL2
catalog :
31694
citations: 12
Reference
Zhang Z, Wang X, Kim M, He D, Wang C, Fong K, et al. Downregulation of EZH2 inhibits epithelial-mesenchymal transition in enzalutamide-resistant prostate cancer. Prostate. 2023;: pubmed publisher
Del Rio D, Masi I, Caprara V, Spadaro F, Ottavi F, Strippoli R, et al. Ovarian Cancer-Driven Mesothelial-to-Mesenchymal Transition is Triggered by the Endothelin-1/β-arr1 Axis. Front Cell Dev Biol. 2021;9:764375 pubmed publisher
Vedagiri D, Gupta D, Mishra A, Krishna G, Bhaskar M, Sah V, et al. Retinoic Acid-Inducible Gene I-Like Receptors Activate Snail To Limit RNA Viral Infections. J Virol. 2021;95:e0121621 pubmed publisher
Cheng F, Dou J, Zhang Y, Wang X, Wei H, Zhang Z, et al. Urolithin A Inhibits Epithelial-Mesenchymal Transition in Lung Cancer Cells via P53-Mdm2-Snail Pathway. Onco Targets Ther. 2021;14:3199-3208 pubmed publisher
Kochanowski P, Catapano J, Pudełek M, Wrobel T, Madeja Z, Ryszawy D, et al. Temozolomide Induces the Acquisition of Invasive Phenotype by O6-Methylguanine-DNA Methyltransferase (MGMT)+ Glioblastoma Cells in a Snail-1/Cx43-Dependent Manner. Int J Mol Sci. 2021;22: pubmed publisher
Yang M, Li Z, Tao J, Hu H, Li Z, Zhang Z, et al. Resveratrol induces PD-L1 expression through snail-driven activation of Wnt pathway in lung cancer cells. J Cancer Res Clin Oncol. 2021;: pubmed publisher
Al Hattab D, Safi H, Nagalingam R, Bagchi R, Stecy M, Czubryt M. Scleraxis regulates Twist1 and Snai1 expression in the epithelial-to-mesenchymal transition. Am J Physiol Heart Circ Physiol. 2018;315:H658-H668 pubmed publisher
Fagoonee S, Picco G, Orso F, Arrigoni A, Longo D, Forni M, et al. The RNA-binding protein ESRP1 promotes human colorectal cancer progression. Oncotarget. 2017;8:10007-10024 pubmed publisher
Wu T, Chang S, Li C, Hsu Y, Chen T, Lee W, et al. Severe Hepatitis Promotes Hepatocellular Carcinoma Recurrence via NF-?B Pathway-Mediated Epithelial-Mesenchymal Transition after Resection. Clin Cancer Res. 2016;22:1800-12 pubmed publisher
Xie Y, Liu S, Lu W, Yang Q, Williams K, Binhazim A, et al. Slug regulates E-cadherin repression via p19Arf in prostate tumorigenesis. Mol Oncol. 2014;8:1355-64 pubmed publisher
Zirkel A, Lederer M, Stöhr N, Pazaitis N, Huttelmaier S. IGF2BP1 promotes mesenchymal cell properties and migration of tumor-derived cells by enhancing the expression of LEF1 and SNAI2 (SLUG). Nucleic Acids Res. 2013;41:6618-36 pubmed publisher
Fujita N, Jaye D, Kajita M, Geigerman C, Moreno C, Wade P. MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer. Cell. 2003;113:207-19 pubmed
product information
Catalog Number :
31694
Product Name :
Snail_pGL2
article :
doi10.1016/S0092-8674(03)00234-4
id4481
pubmed_id12705869
bacterial resistance :
Ampicillin
cloning :
backbonepGL2_Basic
backbone_mutation
backbone_origin
backbone_size5598
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Luciferase
growth notes :
Contains Snail promoter (-1045 to -56) sequence upstream of luciferase
origin :
37
pi :
alt_names
SNAI1
cloning
clone_methodRestriction Enzyme
cloning_site_3HindIII
cloning_site_5KpnI
promoter
sequencing_primer_3
sequencing_primer_5n/a
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesSLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1
geneSNAI1
id6615
genbank_ids
NM_005985
mutation
nameSnail
shRNA_sequence
size989
species
9606
Homo sapiens
tags
resistance markers :
1012
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA