This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pSG5-P190
catalog :
31285
citations: 4
Reference
Masuda T, Maeda S, Shimada S, Sakuramoto N, Morita K, Koyama A, et al. RUNX1 transactivates BCR-ABL1 expression in Philadelphia chromosome positive acute lymphoblastic leukemia. Cancer Sci. 2022;113:529-539 pubmed publisher
Uchihara Y, Tago K, Taguchi H, Narukawa Y, Kiuchi F, Tamura H, et al. Taxodione induces apoptosis in BCR-ABL-positive cells through ROS generation. Biochem Pharmacol. 2018;154:357-372 pubmed publisher
Gudernová I, Foldynova Trantirkova S, Ghannamova B, Fafilek B, Varecha M, Balek L, et al. One reporter for in-cell activity profiling of majority of protein kinase oncogenes. elife. 2017;6: pubmed publisher
Yi S, Lee H, Groffen J, Heisterkamp N. Bcr/Abl P190 interaction with Spa-1, a GTPase activating protein for the small GTPase Rap1. Int J Mol Med. 2008;22:453-8 pubmed
product information
Catalog Number :
31285
Product Name :
pSG5-P190
article :
doi
id4395
pubmed_id18813851
bacterial resistance :
Ampicillin
cloning :
backbonepSG5
backbone_mutation
backbone_origin
backbone_size4076
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
This construct encodes a human chimeric P190-encoding Bcr/Abl oncogene. The construct was made by Leena Haataja in 1993.
origin :
37
pi :
alt_names
P190 BCR/ABL
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5EcoRI
promoter
sequencing_primer_3SV40-pA-R
sequencing_primer_5t7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesABL, BCR-ABL, CHDSKM, JTK7, bcr/abl, c-ABL, c-ABL1, p150, v-abl
geneABL1
id25
aliasesALL, BCR1, CML, D22S11, D22S662, PHL
geneBCR
id613
genbank_ids
mutation
nameBcr-abl fusion protein P190
shRNA_sequence
size10000
species
9606
Homo sapiens
tags
resistance markers :
995
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA