This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
FR_HNF4A2
catalog :
31100
citations: 9
Reference
Emanuelson C, Ankenbruck N, Kumbhare R, Thomas M, Connelly C, Baktash Y, et al. Transcriptional Inhibition of MicroRNA miR-122 by Small Molecules Reduces Hepatitis C Virus Replication in Liver Cells. J Med Chem. 2022;65:16338-16352 pubmed publisher
Lei X, Ketelut Carneiro N, Shmuel Galia L, Xu W, Wilson R, Vierbuchen T, et al. Epithelial HNF4A shapes the intraepithelial lymphocyte compartment via direct regulation of immune signaling molecules. J Exp Med. 2022;219: pubmed publisher
Lu H, Lei X, Winkler R, John S, Kumar D, Li W, et al. Crosstalk of hepatocyte nuclear factor 4a and glucocorticoid receptor in the regulation of lipid metabolism in mice fed a high-fat-high-sugar diet. Lipids Health Dis. 2022;21:46 pubmed publisher
Fráguas Eggenschwiler M, Eggenschwiler R, Söllner J, Cortnumme L, Vondran F, Cantz T, et al. Direct conversion of porcine primary fibroblasts into hepatocyte-like cells. Sci Rep. 2021;11:9334 pubmed publisher
Yang X, Cai W, Sun X, Bi Y, Zeng C, Zhao X, et al. Defined host factors support HBV infection in non-hepatic 293T cells. J Cell Mol Med. 2020;24:2507-2518 pubmed publisher
Guo S, Lu H. Novel mechanisms of regulation of the expression and transcriptional activity of hepatocyte nuclear factor 4α. J Cell Biochem. 2019;120:519-532 pubmed publisher
Aschenbrenner A, Bassler K, Brondolin M, Bonaguro L, Carrera P, Klee K, et al. A cross-species approach to identify transcriptional regulators exemplified for Dnajc22 and Hnf4a. Sci Rep. 2017;7:4056 pubmed publisher
Moore B, Khurana S, Huh W, Mills J. Hepatocyte nuclear factor 4α is required for cell differentiation and homeostasis in the adult mouse gastric epithelium. Am J Physiol Gastrointest Liver Physiol. 2016;311:G267-75 pubmed publisher
Thomas H, Senkel S, Erdmann S, Arndt T, Turan G, Klein Hitpass L, et al. Pattern of genes influenced by conditional expression of the transcription factors HNF6, HNF4alpha and HNF1beta in a pancreatic beta-cell line. Nucleic Acids Res. 2004;32:e150 pubmed
product information
Catalog Number :
31100
Product Name :
FR_HNF4A2
article :
doi10.1093/nar/gnh144
id4333
pubmed_id15520459
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA5/FRT/TO
backbone_mutation
backbone_originInvitrogen
backbone_size5137
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
for Flp mediated site directed integration, tetracycline inducibilty
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3NotI
cloning_site_5NotI
promoter
sequencing_primer_3
sequencing_primer_5na
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesFRTS4, HNF4, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, MODY, MODY1, NR2A1, NR2A21, TCF, TCF-14, TCF14
geneHNF4A
id3172
genbank_ids
NM_000457
mutationsplice variant 2
nameHNF4A
shRNA_sequence
size2250
species
9606
Homo sapiens
tags
locationN terminal on insert
tagMyc
resistance markers :
971
tags :
High Copy
terms :
Hygromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA