This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCAX FLAG APP
catalog :
30154
citations: 8
Reference
Huang J, Huang F, Yang C. Moscatilin Ameliorates Tau Phosphorylation and Cognitive Deficits in Alzheimer's Disease Models. J Nat Prod. 2019;82:1979-1988 pubmed publisher
Lee H, Fan S, Huang F, Chao H, Hsu K, Lin T, et al. 5-Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer's Disease Phenotypes. J Med Chem. 2018;61:7087-7102 pubmed publisher
Fan S, Huang F, Liou J, Yang C. The novel histone de acetylase 6 inhibitor, MPT0G211, ameliorates tau phosphorylation and cognitive deficits in an Alzheimer's disease model. Cell Death Dis. 2018;9:655 pubmed publisher
Rehker J, Rodhe J, Nesbitt R, Boyle E, Martin B, Lord J, et al. Caspase-8, association with Alzheimer's Disease and functional analysis of rare variants. PLoS ONE. 2017;12:e0185777 pubmed publisher
Swaminathan G, Zhu W, Plowey E. BECN1/Beclin 1 sorts cell-surface APP/amyloid ? precursor protein for lysosomal degradation. Autophagy. 2016;12:2404-2419 pubmed
Hosoi T, Kakimoto M, Tanaka K, Nomura J, Ozawa K. Unique pharmacological property of ISRIB in inhibition of A?-induced neuronal cell death. J Pharmacol Sci. 2016;131:292-5 pubmed publisher
Atkin G, Hunt J, Minakawa E, Sharkey L, Tipper N, Tennant W, et al. F-box only protein 2 (Fbxo2) regulates amyloid precursor protein levels and processing. J Biol Chem. 2014;289:7038-48 pubmed publisher
Young Pearse T, Bai J, Chang R, Zheng J, LoTurco J, Selkoe D. A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference. J Neurosci. 2007;27:14459-69 pubmed
product information
Catalog Number :
30154
Product Name :
pCAX FLAG APP
article :
doi10.1523/JNEUROSCI.4701-07.2007
id4221
pubmed_id18160654
bacterial resistance :
Ampicillin
cloning :
backbonepCAX
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3NotI
cloning_site_5EcoRV
promoter
sequencing_primer_3
sequencing_primer_5n/a
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, alpha-sAPP, preA4
geneAPP
id351
genbank_ids
mutationwild type splice variant 751
nameAmyloid Precursor Protein
shRNA_sequence
size2000
species
9606
Homo sapiens
tags
locationN terminal on insert
tagFLAG
resistance markers :
959
958
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA