This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pSG5-CRKL
catalog :
29560
citations: 2
Reference
Nieto Pelegrin E, Meiler E, Martín Villa J, Benito León M, Martinez Quiles N. Crk adaptors negatively regulate actin polymerization in pedestals formed by enteropathogenic Escherichia coli (EPEC) by binding to Tir effector. PLoS Pathog. 2014;10:e1004022 pubmed publisher
Fioretos T, Heisterkamp N, Groffen J, Benjes S, Morris C. CRK proto-oncogene maps to human chromosome band 17p13. Oncogene. 1993;8:2853-5 pubmed
product information
Catalog Number :
29560
Product Name :
pSG5-CRKL
article :
doi
id4159
pubmed_id8378094
bacterial resistance :
Ampicillin
cloning :
backbonepSG5
backbone_mutation
backbone_originStratagene
backbone_size4076
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Crkl pSG5. This construct encodes the human adapter protein Crkl. Crkl is a protein that contains one SH2 domain and two SH3 domains. It can become tyrosine phosphorylated by the c-Abl tyrosine kinase on residue Y207. Crkl is located on chromosome 22q11.21. Gene ID: 1399. HPRD: 03596. NM_005207. The construct was made by Joanne ten Hoeve in 1992/1993.
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3SMAI
cloning_site_5SMAI
promoter
sequencing_primer_3
sequencing_primer_5T7
site_3_destroyed1
site_5_destroyed1
entrez_gene
aliases
geneCRKL
id1399
genbank_ids
NM_005207
mutation
nameCRKL
shRNA_sequence
size1600
species
9606
Homo sapiens
tags
resistance markers :
995
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA